JAMA Internal Medicine

Medicare patients of general internists with higher Longitudinal Knowledge Assessment scores were significantly less likely to receive low-value services, underscoring the role of physician knowledge in reducing unnecessary care. ja.ma/4vqmZGf

Among Medicare beneficiaries with newly diagnosed cancer, #MedicareAdvantage was associated with similarly timely and optimal treatment as traditional Medicare, but with lower cancer drug costs. ja.ma/44UWq0V

💬 Editorial: JAMA Internal Medicine now requires RCTs to rigorously define, systematically assess, and fully report all harms, ensuring a balanced evaluation of risks and benefits per CONSORT guidelines. ja.ma/44UW3n3

💬 Viewpoint: Most lethal #zoonotic #viruses, including Andes virus, lack sufficient transmissibility for global spread. Balanced public health communication is essential to prevent undue alarm. ja.ma/4aHB2ji

Cluster RCT: On-site #POC-RMPCR in nursing homes did not reduce outbreak size or frequency, but reduced ED transfers and enabled faster #antiviral therapy compared to standard off-site testing. ja.ma/4bg9PUW

📢 Call for Papers The editors of @JAMAInternalMed invite the scientific community to contribute studies that will improve our understanding of health equity and the most promising interventions available to optimize it. Read the full call for papers: ja.ma/4vHP5xu

Compared with USPSTF guidelines, a threshold of ≥40 years smoked for #LungCancer screening identified more individuals with highest expected benefit and excluded almost all with lowest benefit, but reduced overall eligibility. ja.ma/4fcVcUG

🔗 This case report describes the electrocardiogram findings of an older adult man with acute chest pain, dyspnea, and altered consciousness. ja.ma/4as1Und

A large sibling-matched cohort study in Hong Kong found no evidence of an association between prenatal paracetamol (acetaminophen) exposure and risk of #Autism or #ADHD in offspring when accounting for unmeasured familial confounding. ja.ma/4vMLPRM

An 8-week telehealth mindfulness group medical visit program for adults with #LowBackPain produced modest but sustained improvements in pain intensity and interference at 6 and 12 months vs usual care. ja.ma/4xXng61

Asynchronous electronic screening prior to #telemedicine visits improved completion and detection rates for unhealthy alcohol use among #veterans in primary care compared with usual staff-administered screening. ja.ma/4b0f8HY

In a national cohort, Black living kidney donors with #APOL1 high-risk genotypes had more than twice the risk of reduced kidney function nearly 20 years after donation, supporting genotyping for better risk stratification. ja.ma/4ekaKpo

In a national cohort, Black living kidney donors with #APOL1 high-risk genotypes had more than twice the risk of reduced kidney function nearly 20 years after donation, supporting genotyping for better risk stratification. ja.ma/4oHlTUX

In a randomized trial, higher financial incentives eliminated racial enrollment disparities in a smoking cessation trial, but did not affect gaps by sex, age, or education. ja.ma/4es5Re5

In a national cohort, Black living kidney donors with #APOL1 high-risk genotypes had more than twice the risk of reduced kidney function nearly 20 years after donation, supporting genotyping for better risk stratification. ja.ma/4xFRpqi

Multilevel stewardship helped reduce inappropriate anticoagulation-antiplatelet therapy, especially among patients with #coronary #artery #disease, according to Jacob E. Kurlander, MD, MS, and C. Seth Landefeld, MD. 🎧 Listen to the full podcast: ja.ma/4xIW4HT

A multilevel stewardship intervention for patients on direct oral anticoagulants was associated with greater reductions in antiplatelet use, especially among those with stable #CoronaryArteryDisease, supporting scalable stewardship models. ja.ma/3QwO0JO

In a national cohort, Black living kidney donors with #APOL1 high-risk genotypes had more than twice the risk of reduced kidney function nearly 20 years after donation, supporting genotyping for better risk stratification. ja.ma/4elQzaB

Among US adults, 2024–2025 COVID-19 vaccination was associated with a 26% lower risk of COVID-19 ED/UC visits, 35% lower risk of hospitalization, and 41% lower risk of critical illness, with effectiveness declining >6 months post vaccination. ja.ma/4vArQVB

Among older adults after #surgery, postoperative #delirium was independently associated with long-term #cognitive decline; rehospitalization did not mediate this association. ja.ma/44d6WAg