Jean-Francois Nankoo

@KebbelChri25685 @RealJamesWoods It simply a lack of creativity from researchers to find a better alternative to animal testing. So NO we don't have to test on animals. Im a researcher btw.

I worked in medical research. Research for a drug is very strict and can take at least a decade. If drugs are being tested to use ultimately in humans it HAS to be first tested on lower mammals like mice. Not being able to test on vertebrates will never tell us if it is safe and effective. We would have to jump immediately into human trials-volunteers. Without even THIS we would end-up with “Covid Vaccine” events. We citizens WERE the guinea pigs! If you don’t want to be an unwilling guinea pig then how will we get enough volunteers for viable safety research???

This alone makes him candidate for one of our most humanitarian heroes in government.

New Research: Sensory–movement underpinnings of lifelong neurodivergence: getting a grip on autism frontiersin.org/articles/10.33… #FrontiersIn #IntegrativeNeuroscience

Dr. Andres Lozano, @DrAlfonsoFasano, and @kalialabs @KBI_UHN highlight the results of the first clinical trial of a new treatment for #Parkinsons, bemdaneprocel, which replaces lost #dopamine by generating new neurons from #StemCells. Read more ➡️ uhnresearch.ca/news/injecting… (3/4)

OH MY FUCKING GOD. YOUR ENTIRE BUSINESS RUNS ON MASSIVE AMOUNTS OF UNPAID LABOUR YOU HYPOCRITICAL SHITGIBBONS.

The 6th #BrainStimConf is officially underway! Mark George and Harold Sackeim kicked things off with opening remarks, followed by insightful plenary talks from @marombikson and @cjstagg. Exciting to see papers from both of my PIs—including my own—among the top downloads of 2024! 🔥 @brainstimj @RobertC21093233

@benjamin_kop @drcarysevans One thing though. The 4nchannel is a lot thicker than the 2 channel. So this will increase the tms to scalp distance. In addition the 4 channel is much more focused than the 2 channel. So it may be that the 4 channel is simply not engaging enough neurons. Just an idea.

@JFNankoo @drcarysevans Of course, it remains possible that the originally reported effects are valid! If future work included double blinding and validated TMS neuronavigation, that would go a long way in demonstrating how robust these effects are when using the same equipment!

Effects of 5Hz-rTUS (tbTUS) on corticospinal excitability are less robust than we initially thought. Check out my new preprint with @drcarysevans and Po-Yu Fong showing that offline excitatory TUS-TMS effects don't replicate. Thread below 👇 doi.org/10.1101/2024.1…

@benjamin_kop @drcarysevans Interesting. I wonder why there are studies replicating it? If it is a bias then we have to consider a systematic bias in multiple labs. FYI - I have no personal attachment to any protocols - I am just curious.

@JFNankoo @drcarysevans It’s unlikely to be a difference in equipment for a couple reasons! For one, our acoustic profile in the brain was very similar. Second, I piloted the study at Donders using a 2-element transducer and also didn’t see any evidence of excitation there.

@benjamin_kop @drcarysevans Since the Zeng result has been replicated multiple times, I wonder if the difference in equipment is the issue. 4 channel vs 2 channel.

@JFNankoo @drcarysevans We ran the study double-blinded only, so with the information we have the discrepancy in results is likely due to double blinding and/or TMS neuronavigation! Even if single blinding like Zeng, neuronavigation would eg still have removed possible unconscious bias in TMS placement

"The future of transcranial ultrasound as a precision brain interface" — Read it on @ResearchGate: researchgate.net/publication/38…

[Motor Cortex] Stanley Chen et al.: "Co-delivery of transcranial focused ultrasound (TUS) and transcranial magnetic stimulation (TMS) can elicit inhibitory after-effect in subjects who showed online inhibition, suggesting that TUS and TMS may interact with each other to produce plasticity effects." doi.org/10.1016/j.clin…

New tools. New treatments. New discoveries. 🔬🩻💉❤️ Check out these health research stories about different ways the health research community is working to help people in Canada be healthy: cihr-irsc.gc.ca/e/53817.html

It was a pleasure to participate in the Canadian Focused Ultrasound Meeting and present our brand new data on the selective manipulation of attention & cognitive control using transcranial ultrasound stimulation of deep brain areas in humans. Thanks @JFNankoo for the invitation!

@HamidRamezanpou Great work and great presentation.

The 1st Canadian Focused Ultrasound Neuromodulation meeting was a success, with participants from across Canada including Ontario, Alberta, BC, and Quebec. Tomorrow, we continue with the international #FUN24 congress @MaRSDD in Toronto! fun24.ca @JFNankoo @RobertC21093233 @HamidRamezanpou

Day two of #FUN24 kicked off with an outstanding presentation by Emilie Franceschini from Aix-Marseille University @univAMU_Europe @LMA_UMR7031. She discussed how some of the dorsal root ganglion neurons are genetically more responsive to focused ultrasound stimulation and the critical role of deformation in FUS response. The session was moderated by Miriam Klein-Flugge @MKFlugge.

We’re thrilled to welcome the #FocusedUltrasound Neuromodulation Society to @itrusst #FUN24 in Toronto! Ready for an exciting second day filled with great presentations.

Our second invited speaker, Ghazaleh Darmani, delivered an excellent lecture on how #LFPs change in response to #focusedultrasound stimulation in #ParkinsonsDisease patients in the second session that was moderated by Elsa Fouragnan @EFouragnan from @PlymUni.

We enjoyed three excellent presentations on #focusedultrasound simulations and new systems in the first session of #FUN24. Thanks to Elly Martin @ellymmartin, Will Grissom @wgrissom, Bradley Treeby for their insights! @cfcaskeyPhD @huiwen_luo @ian_simcock @TulikaNan @IoanaGrigoras4 @cjstagg @UCL_Ultrasound

Exciting day in the lab! We've just received our new @Fraunhofer focused ultrasound device. Can't wait to dive into research with this cutting-edge technology! @JFNankoo @RobertC21093233