Joel Flores

🔬 New Meta-analysis on Fecal elastase-1 (FE-1) for exocrine pancreatic insufficiency. • 200 µg/g → Sens. 94 %, Spec. 69 % • 100 µg/g → Sens. 88 %, Spec. 82 % 👉 Excellent screening tool in high-risk patients. ⚠️ Should NOT be used in individuals without suggestive symptoms.

A simple ice-water rinse after ERCP halves post-procedure pancreatitis. Safe, inexpensive, and easy to apply. Should we start doing it? @tasaycohu @ResisDigesHUVH

Amazing days #EPC2025 sharing with friends and colleagues. Thanks @EurPancClub to accept our work. Great meeting in Düsseldorf! @vallhebron @ResisDigesHUVH @SCDigestologia @SCPancrees @MoleroXavier @evaqueroraya @JFlores_Gastro

Proud of our fellow representing our work at #UEGweek25. Case accepted! @my_ueg @ResisDigesHUVH @JFlores_Gastro

🔬 Who Should Get Screened for Pancreatic Cancer? Insights from #ESMOGI25 🔎 📌 High-Risk Germline Mutations 🧬 STK11 (Peutz-Jeghers): RR ~132 | Lifetime risk: 11–36% 🧬 PRSS1 (Hereditary Pancreatitis): RR 53–87 | Risk up to 55% by age 70 🧬 CDKN2A (FAMMM): RR 20–40 | Risk 17–25% 🧬 TP53 (Li-Fraumeni): RR 7–10 | Risk 5–15% 🧬 BRCA2 / PALB2 / ATM: RR 2–6 | Risk ~5–10% 🧬 FPC (Familial Pancreatic Ca): RR 4–32 (family burden dependent) 📊 Even rare syndromes (like STK11, CDKN2A, TP53) carry >10× risk vs general population! 💡 Emerging targeted trials: • TNG260 + pembro for STK11 (NCT05887492) • TCR-T cell therapy in dev for TP53 👉 Pancreas screening may be justified in select germline carriers (RR >5 + FHx) #PancreaticCancer #Genomics #GIcancer #PrecisionOncology @myESMO @MyriamChalabi @CathyEngMD @OncoAlert @OncBrothers

The UEG guidelines for pain management in acute pancreatitis was presented at EPC in Dusseldorf and was very well attended. Sufficient pain management is an unmet need that needs more attention @epc @esnm_eu @my_ueg

🚨 Breaking news 🚨 @my_ueg @ResisDigesHUVH

Grateful to @sepdigestiva for their recognition and, indebted to my colleagues who played a vital role in this research. Thank you all. #CongresoSEPD23 @vallhebron @RomeFoundation @DrPalssonUNC @concepmari @aranizagirre

It has been a great pleasure to share the findings of our study on Proctalgia fugax according to RFGES at the #CongresoSEPD23 @RomeFoundation @DrPalssonUNC @AlonsoCotoner @sepdigestiva @vallhebron

Great participation of our residents at #CongresoSEPD23 - 1 Oral communication - 2 Short oral communications - 3 e-Posters 🥇 Best oral communication on small and large bowel section @vallhebron @sepdigestiva

#CongresoSEPD23 La Dra. @Albajmasip nos presenta los resultados de la “Evaluación de índices serológicos en el diagnóstico de la esteatosis hepática en España”. #Esteatosis #Hepatología @jesusriveraest @LHuvh @sepdigestiva

Tratamiento de la pseudo obstrucción intestinal tipo ganglionitis mesentérica con antiTNF a cargo del Dr. Pablo Pastor #CongresoSEPD23 #MotilidadVH #UACC @sepdigestiva @MalageladaC @alcala_glez_LG @nataliaborruel

La Dra. María Pérez nos presenta los resultados de la prevalencia de #DisfagiaFuncional en España en base a la #RFGES #CongresoSEPD23 @sepdigestiva @RomeFoundation

@carlospetrola Intenso te va mejor 😂

Con 42 años aún no tengo definido con que categoria encajo.

@DeMadaria @XaviBarberUMH Sesgo de Berkson, probablemente se haya seleccionado los sujetos a estudio (los huevos) de una cohorte con exposición al factor de riesgo.

I need a statistician, what is the probability that six eggs will all have double yolks? @XaviBarberUMH

Not an appropriate indication for endoscopy 😅

#ECYG 2023 *Bloating and abdominal distension* Outstanding presentation on the physiopathology, approach, and the treatment of abdominal distension by Prof. @jordiserradr @ECYGnews @esnm_eu @ASENEM_ @ResisDigesHUVH #MotilidadVH #DigestivoVH #Motility #NeuroGastro

#ECYG 2023 Diagnosis and follow-up of Pancreatic Cyst Neoplasm 📍MRI better for use tying specific PCN 📍Preferred follow up method ➡️ MRI +/- EUS 📍 EUS recommended if clinical/radiological red flags as initial investigación and/or follow-up #PancreasVH

#ECYG 2023 *Intestinal US and calprotectin as predictors of histological activity in UC* 📍 Increasingly important monitoring tool 📍 Offers a comprehensive assessment of disease activity 📍 May not provide as detailed information about the mucosal appearance as endoscopy

#ECYG PGT - Management of GI bleeding pearls Key Points *Ocult GI bleeding* 📍Suspected small bowel bleeding (SSBB) or Iron deficiency anemia (IDA) ➡️ Capsule endoscopy (❌ 2nd look endoscopy)

#ECYG PGT - Management of GI bleeding Key Points @iangralnek *Tomas Hucl* @drmostafa_1980 @albertomurino @aegastro @my_ueg