Jiang Lab@PennState

Helicon: Helical indexing and 3D reconstruction from one image biorxiv.org/content/10.110… #biorxiv_biophys

The Jiang lab is recruiting postdocs in cryo-EM studies of amyloids, virus/host interactions, and protein complexes relevant to cancers. More details can be found at tinyurl.com/2s7ps95s

More info at jiang.bio.purdue.edu/maskChains

We've developed "maskChains" a tool that neatly masks map density around your protein model chains of interest (available in the ChimeraX Toolshed). maskChains is particularly useful for amyloids as it retains extra densities in the layer of the specified chains. Give it a try!

Thanks to NSF REU student @_bongaby, our protein/ligand binding web app now supports the binding of one ligand to multiple proteins, helping you understand off-target binding of drugs. jiang.bio.purdue.edu/multi-binding

How much protein and ligand are needed to ensure >90% binding? We have developed a Web app (#protein-ligand-binding" target="_blank" rel="nofollow noopener">jiang.bio.purdue.edu/software/#prot…) to show how the fraction of binding is related to binding affinity, protein and ligand concentration, not just protein:ligand molar ratio

Beautiful experience at M&M 2023 (Minneapolis); @NCCATinfo @SLAClab @CryoEM_PNCC @NCITUinfo @PurdueScience @PurdueLifeSci @JiangLabCryoEM #CRYOVR

M&M 2023 at Minneapolis @NCCATinfo @SLAClab @CryoEM_PNCC @NCITUinfo @PurdueScience @PurdueLifeSci @JiangLabCryoEM @NIH_CommonFund @CryoEM_PNCC #MM2023Minneapolis #CRYOVR

The Jiang lab at Purdue University is seeking a highly motivated postdoctoral researcher to join our team and work on cryo-EM structural studies of amyloids in neurodegenerative diseases. tinyurl.com/yz86nmer

@ACAxtal Workshop-5: @JiangLabCryoEM showed how CryoVR virtual reality training tools help familiarize users with #cryoEM equipment through a safe and accessible virtual environment. All the training modules demonstrated today are available to download. va.tech.purdue.edu/cryoVR/index.p…

Proud to share the first major work from my PhD with @JiangLabCryoEM. We used cryoEM to determine the atomic structures of the first human brain-derived prion protein filaments from Gerstmann–Sträussler–Scheinker disease. link.springer.com/article/10.100…

Book your room for #acameeting2022 #aca2022meeting. The @NIH_CommonFund Service Centers & Curriculum Development partners are ready to train the next generation of #cryoEM practitioners. Sign up for WK-5: CryoEM sample preparation training on 7/29/2022. amcac.memberclicks.net/aca-wk5

@JiangLabCryoEM & Yingjie Victor Chen of @PurdueScience shared how the @CryoVR system familiarizes users with #cryoEM equipment in a safe and accessible, virtual environment. TAs Daoyi and Kadir came onsite to help with the hands-on demo. va.tech.purdue.edu/cryoVR/

Happy to have our ⁦@refeynit⁩ #massphotometry system in house in the #cryoEM center ⁦@UWBiochem⁩ ⁦@UWMadisonCALS⁩ ! Come by to try it out!

Learn more about the cryo-EM training experience using CryoVR: ter.li/y9llcb ✨

The Metskas Lab at Purdue is hiring! We use #cryoET and #CLEM to study viruses and microcompartments. Seeking a tech (career8.successfactors.com/sfcareer/jobre…) and a postdoc (contact bio.purdue.edu/People/profile…). #TeamTomo pls RT

Work by our recent PhD graduate Dr. Brenda González (@brenda_agenda) on the structural studies of the Phage G tail is out! This paper describes the contracted and non-contracted states of the Phage G tail sheath. mdpi.com/1999-4915/13/1…

@PurdueScience developed a #VirtualReality training system for #cryoEM called CryoVR. By introducing new users to our equipment through #VR, their training can be done remotely and safely, while still being hands on. @JiangLabCryoEM 🥽 ter.li/kcampv

With a grant from @NIH, @PurdueScience developed #VirtualReality training tools for #cryoEM. Join us on August 11 to see Purdue's @CryoVR in action with professors Yingjie Victor Chen and Wen Jiang. ter.li/5gs5qy

@PurdueScience is expanding access to #cryoEM with its #VirtualReality training tool called @CryoVR. Join us for a special session with professors Wen Jiang and Yingjie Victor Chen on August 11 to learn more! bit.ly/3faZRqP

This month's Acta Neuropathologica cover image is derived from @GraceHallinan, @vidalr01, @JiangLabCryoEM et al's article, "Structure of Tau filaments in Prion protein amyloidoses" link.springer.com/article/10.100…