Jim Wells Lab

Welcome to Cincinnati Children's Research! Follow us to share discoveries across the spectrum of pediatric science. We're probing the foundations of human development and the origins of disease. We're transforming care and improving population health so all children can thrive.

@millsjc67 @Dr_MadThreats @JosephBurclaff Congratulations on the great work Maple, Jason and colleagues!

Congrats to @Dr_MadThreats and Masa and so many others in the lab and formerly in the lab like @JosephBurclaff for this comprehensive treatise on how a stem cell uses metabolic queues to choose a differentiates fate.

To learn more about the story behind the paper, we caught up with first author J. Guillermo Sanchez @Guillerm0Sanchz and corresponding author Jim Wells @JimWellsLab, an endowed professor in the Division of Developmental Biology @CincyChildrens: journals.biologists.com/dev/article/15…

Human organoids dish up insights into intestinal patterning Read this Research Highlight showcasing work from J. Guillermo Sanchez @Guillerm0Sanchz, Jim Wells @JimWellsLab and colleagues @CincyChildrens: journals.biologists.com/dev/article/15…

Congrats to Dr. @Guillerm0Sanchz! Got to enjoy his impressive defense with another exceptional @JimWellsLab alum @_HAMcCauley. Can’t wait to start working together in June.

Excited to finally be able to share my thesis work in the @JimWellsLab. If you want to learn more about the role of RFX6 in intestinal development and function, do I have something for you!! @Dev_journal journals.biologists.com/dev/article-ab…

What a better way to close out the meeting than with this awesome panel discussion. Thanks to all the organizers, speakers and participants, it was a blast to have @ISSCR in Cincinnati. @CuSTOMOrganoids @CincyChildrens

Best part of conferences! Former and current members of the lab reunion @ISSCR @CuSTOMOrganoids

Kicking off day 2 of @ISSCR Cincy hearing from @MingxiaGu about her work on vascularizing lung and gut iPSC-derived organoids. @CuSTOMOrganoids

Kicking off the last session of Day 1 #ISSCRCincy is @MummeryLab with a fantastic update on her work on hpsc-derived cardiovascular tissue to study disease. @ISSCR

Exciting update to close the morning session from @morris_lab on the reprogramming of mesenchymal progenitors and their effects on cell lineage @ISSCR #ISSCRCincy

Opening session of ISSCR Cincinnati International Symposium @ISSCR @CuSTOMOrganoids

@JimWellsLab presenting new and exciting data on #organoids at the @tmcddc symposium @BCMFromtheLabs @millsjc67 @EstesLab_BCM @NIDDKgov

👀 Don't miss this study from @Muneralab & @JimWellsLab in @CellStemCell! Learn about how a diverse population of immune cells co-develops in pluripotent stem cell-derived human colonic #organoids. 🧫 ➡️ bit.ly/49jZxk4

Happy to share our latest paper led by @Muneralab and Dan Kechele where we characterize hPSC-derived human colonic organoids with codeveloping immune system. cell.com/action/showPdf…

@TakebeLab representing @CuSTOMOrganoids and @CincyChildrens at the Organoids Symposium in Heidelberg with an amazing talk on multi-zonal iPSC-derived liver organoids @EMBLEvents

@JimWellsLab is modeling human NeuroG3 mutations using #intestinal #organoids. Very cool project and I love the immunostaining! #GESRC

Delegates & faculty discussing the latest advances in stem cell biology & regen. medicine en route to a beautiful remote beach Can you spot Austin Smith, Agnete Kirkby, Kim Jensen, Jim Wells, Cedric Blanpain, Christine Mummery, Sharaghim Tajbakhsh, Elisa Laurenti? #SCSC2023

The true cost of science’s language barrier for non-native English speakers nature.com/articles/d4158…

@GGuaschResearch @MaximeMMahe @MarcoBruschi10 @CancerImmunoAMU Thanks for organizing such an amazing course! It was a great time!

Such a wonderful group of scientists @MaximeMMahe @MarcoBruschi10 @JimWellsLab that share their work and passion to the next generation …Thanks @CancerImmunoAMU