Jordana-Waserman Lab

Sequential Switching Through IgG1 is Redundant for Allergic Reactivity and Memory to Allergens biorxiv.org/cgi/content/sh… #biorxiv_immuno

@allyssaphelps is PhD candidate in the @Jordana_Lab who is changing the world by understanding the mechanisms underlying treatment of peanut allergy #WomenInScience #InternationalDayofWomenandGirlsinScience

A Distinct Phenotype of Polarized Memory B cell holds IgE Memory biorxiv.org/cgi/content/sh… #bioRxiv

A new @McMasterU research institute with a multidisciplinary focus offers hope for people who suffer from life-threatening #allergies. @schroederfdn @Jordana_Lab @CHILDSTUDY ow.ly/em3T50Lt609

Our protocol to desensitize #mastcells after polyclonal #IgE #sensitization is available in @STARProtocols #IISPrincesa, @CNB_CSIC @UFVinvestiga @MacDeptMed @SEAIC_Alergia @EAACI_JM @MontePerdido31 star-protocols.cell.com/protocols/2067

Building on a long history of leadership in allergy and asthma research #McMasterU, the Schroeder Allergy and Immunology Research Institute has made groundbreaking discoveries in the field of allergy research @MacImmunology #allergy ow.ly/6rx350L2t9N

@Jordana_Lab @jfekoenig @allyssaphelps continue to be trailblazers in allergy immunotherapy research! healthinsight.ca/wellness/livin…

A huge congratulations to our very own @jfekoenig for his @MSU_McMaster Teaching Award! Keep up the amazing work! #brighterworld @machealthsci tinyurl.com/2afn5c95

A huge congratulations to Vitoria Olyntho, recipient of the BHSc Summer 2022 Research Scholarship! She will be completing her research with the @Jordana_Lab. We look forward to the amazing research you will produce! @machealthsci

@liza_allergist @FrontAllergy but it’s unclear whether this would impart sustained protection, or what we refer to as a “disease-transformative” therapy.

@liza_allergist @FrontAllergy Work from H Oettgen and others suggests that IgG4 inhibits MC/basophil activation through FcyRIIb and, perhaps, through sequestering allergen prior to its engagement with receptor-bound IgE. So IgG4 MAb treatment may ameliorate adverse events during OIT, similar to omalizumab...

We are pleased to share our new review in @FrontAllergy on current and prospective treatments for food allergy 1/ frontiersin.org/articles/10.33…

New Research: The Road Toward Transformative Treatments for Food Allergy frontiersin.org/articles/10.33… #Allergy

A tremendous effort led by @allyssaphelps

Here, we discuss the immunobiology which underlies the persistence of IgE memory to food allergens, current/experimental treatments, and our perspective on future avenues to establish “disease-transformative” therapies. 3/

This review highlights that SLIT is a safe and effective treatment that considerably reduces symptoms and medication requirements in AR and improves quality of life. ▶️ annallergy.org/article/S1081-…

Joshua F. E. Koenig from the @Jordana_Lab at @McMasterU explains a novel #alarmin involved in #allergic responses. A “Groundbreaking Discoveries in Immunology” article. #Allergy_Journal 🔗 onlinelibrary.wiley.com/doi/epdf/10.11…

Great talk Emily 🎉

We are honoured to have hosted Dr. Marc Jenkins as a keynote speaker at this years Perey Symposium! Dr. Jenkins gave a fantastic talk on his latest work identifying antigen specific CD4+T cells.