Journal of Experimental & Clinical Cancer Research

New!🍀 Bridging phenotype and function in #bladdercancer using immuno-competent #organoids and ex vivo drug screening Read it here👇 link.springer.com/article/10.118… #TumorMicroenvironment #Immunotherapy #SpatialHeterogeneity

New!🥳 #Circulatingextracellularvesicles from early-stage lung cancer patients trigger endothelial activation to drive pre-metastatic niche formation through synergistic miR-29a and C4A signaling Full text⏬ link.springer.com/article/10.118… #Inflammation #LungCancer #Metastasis

bit.ly/496LJLr @BioMedCentral

📢New Collection opens for submissions! 𝐈𝐧𝐬𝐢𝐠𝐡𝐭𝐬 𝐢𝐧𝐭𝐨 𝐭𝐡𝐞 𝐫𝐞𝐥𝐚𝐭𝐢𝐨𝐧𝐬𝐡𝐢𝐩 𝐛𝐞𝐭𝐰𝐞𝐞𝐧 𝐦𝐞𝐭𝐚𝐛𝐨𝐥𝐢𝐬𝐦 𝐚𝐧𝐝 𝐜𝐚𝐧𝐜𝐞𝐫 Look here the details 👇 link.springer.com/collections/ge… #Metabolomics #Proteomics #Ferroptosis #Oxidativestress #Inflammation

Just published! 🥳 𝐂𝐚𝐝𝐡𝐞𝐫𝐢𝐧 𝟏𝟕 𝐚𝐧𝐝 𝐝𝐢𝐠𝐞𝐬𝐭𝐢𝐯𝐞 𝐜𝐚𝐧𝐜𝐞𝐫𝐬: 𝐟𝐫𝐨𝐦 𝐝𝐢𝐚𝐠𝐧𝐨𝐬𝐭𝐢𝐜 𝐭𝐨 𝐭𝐡𝐞𝐫𝐚𝐩𝐞𝐮𝐭𝐢𝐜 𝐨𝐩𝐩𝐨𝐫𝐭𝐮𝐧𝐢𝐭𝐢𝐞𝐬 link.springer.com/article/10.118… #Cadherin17 #DigestiveCancers #TherapeuticTarget

New!🩸 #Liquidbiopsy reveals the immune status and protein profiles linked to CTC burden and clinical outcomes in metastatic #breastcancer Open access🔓 link.springer.com/article/10.118… #CirculatingTumorCells #CirculatingImmuneCells

Online!🌷 Progress and challenges in the development of advanced pancreatic cancer #organoids Full Review 👇 link.springer.com/article/10.118… #Hypoxia #PancreaticDuctalAdenocarcinoma #HypoxiaInducibleFactor #ExtracellularMatrix

New! 👀 #HSP27 functional switch drives castration-resistant #prostatecancer via mTOR pathway activation, highlighting promising combination therapies Look here👇 link.springer.com/article/10.118… #CastrationResistantProstateCancer #Sapanisertib #PatientDerivedOrganoids

New!🔬 The double-edged sword role of tumor-associated macrophages: preventing or causing resistance to #immunotherapy Full text 👇 link.springer.com/article/10.118… #TumorAssociatedMacrophages #TumorMicroenvironment

New👇 #𝐄𝐨𝐬𝐢𝐧𝐨𝐩𝐡𝐢𝐥𝐬 𝐢𝐧 𝐬𝐨𝐥𝐢𝐝 𝐜𝐚𝐧𝐜𝐞𝐫𝐬: 𝐬𝐞𝐧𝐭𝐢𝐧𝐞𝐥𝐬, 𝐩𝐫𝐞𝐝𝐢𝐜𝐭𝐨𝐫𝐬, 𝐚𝐧𝐝 𝐭𝐡𝐞𝐫𝐚𝐩𝐞𝐮𝐭𝐢𝐜 𝐚𝐥𝐥𝐢𝐞𝐬 Free access💻 link.springer.com/article/10.118… #TumorMicroenvironment #PrognosticBiomarker #Immunotherapy

Online!🍹 SNRPC promotes #chemoresistance in #Wilmstumor via the NF-κB-CXCL17 axis regulating M2-Type TAMs infiltration and targeted #nanotherapy research For free📲 link.springer.com/article/10.118… #NanodrugDelivery #TumorAssociatedMacrophages

New! 𝐓𝐡𝐞 𝐫𝐨𝐥𝐞 𝐨𝐟 𝐭𝐡𝐞 𝐭𝐮𝐦𝐨𝐫 𝐦𝐢𝐜𝐫𝐨𝐞𝐧𝐯𝐢𝐫𝐨𝐧𝐦𝐞𝐧𝐭 𝐢𝐧 #𝐝𝐫𝐮𝐠𝐫𝐞𝐬𝐢𝐬𝐭𝐚𝐧𝐜𝐞 𝐚𝐜𝐪𝐮𝐢𝐬𝐢𝐭𝐢𝐨𝐧 𝐢𝐧 𝐥𝐮𝐧𝐠 𝐬𝐪𝐮𝐚𝐦𝐨𝐮𝐬 𝐜𝐞𝐥𝐥 𝐜𝐚𝐫𝐜𝐢𝐧𝐨𝐦𝐚 👇 link.springer.com/article/10.118… #TumorMicroenvironment #LungSquamousCellCarcinoma

Just Published!☀️ 𝐓𝐡𝐞 𝐚𝐫𝐲𝐥 𝐡𝐲𝐝𝐫𝐨𝐜𝐚𝐫𝐛𝐨𝐧 𝐫𝐞𝐜𝐞𝐩𝐭𝐨𝐫, 𝐂𝐈𝐈𝐓𝐀 𝐚𝐧𝐝 𝐇𝐋𝐀-𝐈𝐈: 𝐰𝐡𝐨 𝐢𝐬 𝐰𝐚𝐭𝐜𝐡𝐢𝐧𝐠 𝐭𝐡𝐞 𝐰𝐚𝐭𝐜𝐡𝐝𝐨𝐠? Look here⏬ link.springer.com/article/10.118… #ArylHydrocarbonReceptor #CIITA #HLAclassII #AntigenPresentation

New!😀 Tumor-targeted IL2 promotes specific #CD8+ T cells private clonal expansion enhancing #lymphoma control For free📲 link.springer.com/article/10.118… #Immunotherapy #DiffuseLargeBcellLymphoma

Online!😎 Recapitulating the #tumourmicroenvironment: advancing personalised #radiationtherapy through #organoid technology Full paper🔽 link.springer.com/article/10.118… #Hypoxia #Heterogeneity

Now online!📲 Cell-of-origin and genetic drivers define advanced #bladdercancer subtypes and potential therapeutic response in mouse models Look here 👇 link.springer.com/article/10.118… #PreclincalModels #MolecularSubtypes

Published ✅ #Icaritin eliminates tumor-associated macrophages via STX16-dependent #extracellularvesicle delivery of autophagosomes from #hepatocellularcarcinoma cells Full text👇 link.springer.com/article/10.118… #HistoneLactylation #TumorAssociatedMacrophage #Metabolism #Autophagy

New!🍩 Endothelial cell-derived IGFBP7 suppresses #angiogenesis and tumor progression in #colorectalcancer via the VAPA-TGF-β1 pathway Full text🧐 link.springer.com/article/10.118… #TumorMicroenvironment #Inflammation #TGFβ1signalingpathway

Online!💐 Rewiring tumor #cytokine networks to enhance #immunecheckpointblockade: mechanisms, engineering, and clinical translation Full study👇 link.springer.com/article/10.118… #TumorMicroenvironment #OncolyticViruses

New!📲 Uncovering a novel treatment strategy: #sodiumbutyrate overcomes #cisplatinresistance in the #oralsquamouscellcarcinoma by inducing #ferroptosis Open access🔓 link.springer.com/article/10.118…