Jens Preben Morth 🇪🇺 🇩🇰 🐾 🌍

332 posts

Jens Preben Morth 🇪🇺 🇩🇰 🐾 🌍 banner
Jens Preben Morth 🇪🇺 🇩🇰 🐾 🌍

Jens Preben Morth 🇪🇺 🇩🇰 🐾 🌍

@Jpmorth

Professor at DTU Bioengineering - Structural enzymology and membrane proteins. My tweets are my personal views

DTU, Denmark Katılım Ocak 2014
227 Takip Edilen153 Takipçiler
HRT World
HRT World@dbh_genelmerkez·
Greenland is a part of Denmark. Those who want to take Greenland declare war on Denmark before Greenland. Since Denmark is a part of NATO and Europe, Trump cannot go further than barking and intimidating.
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Kresten Lindorff-Larsen
Kresten Lindorff-Larsen@LindorffLarsen·
Crystallographer trying AlphaFold for the first time
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Jens Preben Morth 🇪🇺 🇩🇰 🐾 🌍
@MBrgger @ArabiYa86 Hvis hun som du beskriver allerede er blevet myrdet sammen med sine børn, så tænker jeg ikke hun er i stand til at nægte nogen noget. Ser nu heller ikke nogen ligheder mellem den generelle præmis du stiller op og det der sker nu ...
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Mads Brügger
Mads Brügger@MBrgger·
Men det som @ArabiYa86 mangler at forestille sig er forspillet, hvor terrorister dukker op, ud af det blå, og myrder hende og hendes børn. Spørgsmålet er så om hun efterfølgende ville nægte disse mordere vand og elektricitet.
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Jens Preben Morth 🇪🇺 🇩🇰 🐾 🌍
@PoulNissen hmm, a beer once in a while does make me happy though, that is a beneficial effect. I think if we stay below the 100 grams per week (7 beers), their lowest point on the y-axis, we should be fine... or?
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Poul Nissen🇩🇰🇺🇦
Poul Nissen🇩🇰🇺🇦@PoulNissen·
In conclusion: Alcohol has no beneficial effects at all, but negative effects at any level
Crémieux@cremieuxrecueil

Everyone knows that alcoholism is bad. Drink too much, you'll fry your brain, or so the wisdom goes. But it's also common knowledge that a little bit of alcohol is good for you. I mean, just take the conventional epidemiological result: Clearly people who used to drink and people who never drink do worse than the people who drink a bit. And when people start drinking even more than a bit, they look a little better. Beyond that, they start to look a bit worse, but at no point are they worse than the non-drinkers. Right? The problem with the conventional analysis is that selection is at play. The people who don't drink at all and the ex-drinkers are selected into not drinking in weird ways. For example, an ex-drinker might be someone who was a heavy drinker in the past; a never-drinker might be a socially odd person. Who knows! But the potential that they're not normal is very much there. It would be unethical to run human experiments to figure out what alcohol does, so, how can we know what alcohol does to health? With a clever little method called Mendelian Randomization, or MR. MR is basically an answer to the question What if I used genes as instrumental variables? Using Chinese data and genes that affect alcohol metabolism, that's exactly what Millwood et al. did! Since the alcohol metabolism genotypes they used should be otherwise independent of risk, everything should be good to go for using these as predictors of alcohol's effects. But just to be sure: one of the ways we know these genotypes don't have independent effects is that there were no effects in women, who, for cultural reasons, are pretty close to being non-drinkers. Just take a look at the male-female difference in drinking! So putting this wonderful genetic predictor to use, we can finally see what alcohol actually does. Well, the effect of the unconfounded difference in alcohol consumption is that, when it comes to heart health, alcohol doesn't seem to do much, rather than being a bit protective. But the heart isn't everything. There's certainly more! Alcohol did increase risk for ischemic stroke, intracerebral hemorrhage, and total strokes. Not only that, but in another study using a similar method, alcohol increased hypertension, blood pressure, waist circumference, waist-to-hip ratio, fasting blood glucose, and triglycerides. But, consistent with these results, in that paper it didn't seem to have a significant effect on cardiovascular disease or coronary heart disease, and it both increased HDL and decreased LDL. In aggregate, alcohol is likely to be bad for your health at any level, but selection into disuse means the downsides have been hidden in traditional analyses. And even if alcohol doesn't negatively impact heart health on its own, the fact that it's not protective and it increases other risks means it's risky on net. Sources: thelancet.com/journals/lance… nature.com/articles/srep1…

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Björn Schumacher
Björn Schumacher@schumacherbj·
When you enter the university administration building
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The Struggling Scientists
The Struggling Scientists@TheStrugglingS4·
At what stage do you feel you can call yourself an expert in your field?
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Poul Nissen🇩🇰🇺🇦
Poul Nissen🇩🇰🇺🇦@PoulNissen·
@Jpmorth - mest fordi alle skulle lade som om det var en særlig burger de lavede. Men alt var så klart en superpositiv oplevelse, både som tilhører og panel/eventdeltager - intet slår det fysiske møde i debat!
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