Kristian RJ

By multi-model, we mean EEG, MRI, fMRI, and PET; by deep, we mean add psychometrics, cognition, genetics, blood samples, health care records, and the Danish registries... 🎯 We have great minds & diverse methods @CopenhagenNeuro to study #MDD heterogeneity and improve treatment.

New data, new findings, new preprint! 🧵 Here are the results from the first psychedelic simultaneous PET-MRI study mapping LSD's receptor binding, blood flow changes, and functional connectivity. medrxiv.org/content/10.110…

@AM_Doornweerd Nice study and impressive data size given the Covid-constrains.

Belated post, but we have 2 new papers out! 📑 We used a cross-over design to study emotion regulation & fear learning during menstrual cycle phases, OC use, and IUD use. A short 🧵1/4

The paper provides comprehensive age and gender-stratified norms for all scales. 📨Write to me for the paper (it is paywalled, sorry) doi.org/10.1080/080394…

😷 😟Important notice: Recent Danish SCL-10 norms from 2020 during the COVID lockdown show unusually high distress levels. This data from an abnormal period isn't suitable as a population norm. I recommend using the gender-specific 2000 norms. #COVID19 #Psychiatry

In my new paper in the Nordic Journal of Psychiatry, I provide gender and age-stratified Danish mental health norms for clinical scales: Brief Symptom Inventory (BSI-53, BSI-18), ADHD scales, and SCL-10. doi.org/10.1080/080394… 👇

💡 Conclusion: LDAEP is not useful as a biomarker for suicide research or prevention in MDD. We need to look elsewhere for approaches to identifying high-risk individuals. 🔗 sciencedirect.com/science/articl… #Depression #Suicide #Neurobiology #EEG

For LDAEP, we found: ❌ No association with and past suicide attempts. ❌ No correlation with suicidality. ❌ No association with suicidality during 12 weeks after EEG. This held true across the meta-analysis, in the independent cohort, and in the updated meta-analysis. [4/4]

📢 New research alert! Does the EEG biomarker LDAEP link to suicidality in Major Depressive Disorder (MDD)? 🧠 Our meta-analysis and independent cohort study reveal key findings. Dive in! 🧵 #depression 🔗 sciencedirect.com/science/articl… [1/5]

Key takeaway: Depression treatment may involve more complex brain changes than previously thought. Our results highlight the need to consider sex differences and challenge simplified growth models of antidepressant action. #Psychiatry

Our findings suggest antidepressants may work through synaptic refinement rather than volume growth. The quality of neural circuits might matter more than size when it comes to treatment response. 🧠

New paper: We investigated hippocampus volume changes during SSRI treatment in #depression in humans. Contrary to expectations, the hippocampus didn't enlarge - it actually decreased in volume in patients who responded to treatment. 💊 sciencedirect.com/science/articl…

@chiccorampazzo @AlyceRaybould @peterampazzo @rosssbarker Interesting paper. So, the top apps in high-income countries are Flo, Clue and Periode Tracker Light. How common do you estimate "built-in" trackers in other apps (e.g. Fitbit) or mobile phone systems (e.g. iOS 13+ Cycle Tracking in Health app)?

1/ New preprint on fertility tracker apps with @AlyceRaybould, @peterampazzo, @rosssbarker, and Doug Leasure. The market for mobile phone apps tracking menstrual cycles has grown in recent years. The reasons for their use have implications across multiple disciplines.

@ScholarshipfPhd Yes, please!

Writing in English: Step by Step Book Drop a "YES" in the comments, and I'll send the link to you via DM! 💬

@EikoFried @WileyGlobal Had a dive into the paper today. Good read. Enjoyed the journal's article type: "LONG DIDACTIC PAPER"

Hey @WileyGlobal I would like to get access to my own #OpenAccess paper please ...