
Prof BWT Kay
260 posts

Prof BWT Kay
@KayBwt
Professor of Human Physiology, Nutrition, and Statistics. YouTube creator https://t.co/mRAbHc7pqb.



You may have read that red meat raises TMAO, a compound associated with cardiovascular disease. You may not have read the part where fish raises TMAO approximately fifty times more than red meat does. TMAO, trimethylamine N-oxide, is found directly in saltwater fish at high levels. It is an osmolyte that helps marine animals manage pressure and salinity. When you eat the fish, you eat the TMAO. Eating beef produces some TMAO indirectly through gut bacteria metabolising carnitine. Eating a piece of cod produces a transient TMAO spike that dwarfs anything red meat can manage. A 2020 study in the American Journal of Clinical Nutrition found no significant association between red meat intake and circulating TMAO concentrations. It found a strong positive association with fish intake. Particularly shellfish. Particularly dark-meat ocean fish. So either TMAO is a useful biomarker for cardiovascular disease, in which case eating salmon should be far worse for your heart than eating a ribeye, and the Mediterranean diet should be killing the Greeks faster than the Atkins diet is killing the Americans. Or TMAO is not a useful biomarker for cardiovascular disease, in which case nobody should be using it to scare you off beef. The researchers who flagged it as a worry have not, to date, suggested you stop eating cod. Have a think about why.

There’s been this overdone common misconception that you HAVE to eat animals to get your protein, but the truth is… ALL protein comes from plants.

There’s been this overdone common misconception that you HAVE to eat animals to get your protein, but the truth is… ALL protein comes from plants.

A calorie is a standardized unit of energy - the same regardless whether you eat steak or doughnuts. What actually matters in the body is how that energy is processed: Protein burns 20-30% just digesting it. Refined carbs only ~5-10%. You’re welcome!

Oh man. I just died laughing! Nicola Guess is a registered dietician and nutrition scientist from the UK. Gil Cavalho has interviewed her on his podcast. Apparently Nick Norwitz talks "bollocks" and was involved in a "shit study" with "Dave Keto". You have to watch this takedown. I'm sorry, but Brits instinctively do this sort of thing better then Americans! youtu.be/pvm2Ij5_VR8?si…

Causal effects of inflammation on long-term mortality: A mendelian randomization study ▶️ Chronic low-grade inflammation is currently recognized as a core driver of CVD & mortality. ▶️ Additionally, acute inflammatory episodes contribute to mortality risk through distinct but overlapping pathways, including sepsis, cytokine storm syndromes, & acute cardiovascular events. ▶️ Interleukin-6 (IL6) signaling plays a key role in inflammation & CVD. ✅️ This Mendelian randomization study demonstrates that the IL6/IL6R (Interleukin-6 Receptor) axis has a causal impact on human survival through cardiovascular mechanisms: IL6R exerts a protective effect, whereas IL6 is detrimental. The protective influence of IL6R on atrial fibrillation, coronary artery disease, stroke & lung cancer provides a mechanistic basis for its mortality benefits. Concordant genetic & pharmacological evidence positions IL6R as a promising therapeutic target for CVD prevention, while the neutral findings for CRP & GDF15 support their role as biomarkers rather than causal drivers. ✅️ Collectively, these results identify the IL6 pathway as a key translational target for reducing CVD & mortality. aging-us.com/article/206352… @HealthyFellow

Just started playing with Claude AI and it seems way more accurate with scientific publications than ChatGPT, which got the links wrong 90% of the time. They both get overall picture correct but both get specific studies wrong here and there, always need to double check.

Emotion suppression may increase the risk for earlier death

Biology is not just chemistry, it is code

The study aimed to evaluate the association between the EAT–Lancet diet and the risk of Chronic Kidney Disease. Multiple scoring systems have been invented to evaluate adherence to the EAT-Lancet diet. Pause for a moment to reflect on that. Some plant-biased researchers invented a diet back in 2019... Following this invention, other ‘researchers’ invented scoring systems to measure adherence to this made up diet. Other ‘researchers’ then use these invented scoring systems to measure adherence to this invented diet and its association with chronic conditions... This is the current state of nutritional ‘research’.🙄

Walking ~3,800 steps/day was linked to a 25% lower risk of dementia. And ~9,800 steps/day with about a 50% lower risk. If dementia runs in your family, daily walks are a no-brainer.

"The WHO classified red meat as a carcinogen." Yes. In 2015. Group 2A. Probably carcinogenic to humans. The classification was based on a meta-analysis finding that fifty grams of processed meat per day was associated with an 18 percent increase in relative risk of colorectal cancer. Let me translate that. Relative risk is the change in your odds. Absolute risk is your actual odds. The lifetime absolute risk of colorectal cancer in the general population is roughly 4 percent. An 18 percent relative increase moves it to approximately 4.7 percent. The risk has not doubled. The risk has not tripled. The risk has gone from one in twenty-five to roughly one in twenty-one, and only if you are eating fifty grams of processed meat every day for life. Smoking, in the same classification scheme, increases your relative risk of lung cancer by approximately 1,900 percent. Your risk of lung cancer goes from roughly 1 percent to roughly 20 percent. Group 1 carcinogens, the category processed meat shares with cigarettes, also include: alcoholic drinks, the contraceptive pill, wood dust, salted fish, sunlight, outdoor air in heavily polluted cities, and the profession of being a painter. Group 2A, where unprocessed red meat sits, includes: shift work, drinking very hot beverages, and the profession of being a barber. The classification reflects the strength of the evidence that something causes cancer. It does not reflect how much cancer the thing actually causes. Bacon and tobacco are not in the same league. They share a room because the room is the size of a warehouse.

@KayBwt @whitfieldlewis6 where are we at on this?

@KayBwt Well you saw my reply so that’s a positive. 😊 If you replied to a post with large number of replies then it’s easier to go to your profile to see your own replies under the replies tab. You will never find it under the original post Good luck, sometimes Twitter is just glitchy

@KayBwt There is a X help website. Never used it, my sure it’s all AI. 🤖 But it might have something help.x.com/en

Any one individual person's scans are proof of absolutely nothing of any prognostic nor mechanistic value to society at large. It seems my sadly ill-educated friend that you have a very long way to go in your learning about epistemology. Go well...

@whitfieldlewis6 @KayBwt I'm happy to hear and entertain any argument anyone wants to make. Just as soon as they've done what I've done. Posted all their artery scans online. Otherwise the world is divided into two camps. Wankers who have no balls, and non-wankers who do.

So let me get this straight... You, a layperson it seems, somehow knows more about cardiovascular pathophysiology than I do? LMAO. Secondly, you could do with some training in logic, it seems... If you want to claim something is unsafe, its YOUR responsibility to prove it.