James Kirby

Burkholderia cepacia causes disease in 🫁 of people with cystic fibrosis, an environment totally unlike standard susceptibility testing conditions. Today at #ASMicrobe Anusha Shukla presented her work on Bcc in artificial sputum medium 🧫🥼🧪 TBKLab.org

Did you know that avibactam has intrinsic antibacterial activity, mediated by inhibition of penicillin-binding protein 2? Here’s the amazing Dr. Michelle Naegeli @drshigelly presenting a poster from our lab today at #ASMicrobe

Yanqin Huang of ⁦@KirbyLabMicrobe⁩ presenting on the all-oral triple combination of omadacycline + azithromycin + clofazimine for M. abscessus #ASMicrobe

Neglected 80-year-old antibiotic is effective against multi-drug resistant bacteria eurekalert.org/news-releases/… via @EurekAlert

New postdoctoral position in structural biology of ribosome and RNA-ligand interaction to elucidate mechanism of action and as a foundation for antimicrobial discovery in the laboratory of scientific collaborator, Ed Yu, Case Western. See full posting. kirbylab.org/uploads/4/4/6/…

Congratulations to Yoon-Suk on his new manuscript, where nanoluciferase and Legionella pneumophila meet! - The Kirby Laboratory kirbylab.org/1/post/2023/02…

RND Pump-Mediated Efflux of Amotosalen, a Compound Used in Pathogen Inactivation Technology to Enhance Safety of Blood Transfusion Products, May Compromise Its Gram-Negative Anti-Bacterial Activity | mSphere journals.asm.org/doi/10.1128/ms…. Our new manuscript!

📰 Publication alert! 🚨 Congrats to former PGY2 resident @BriFrescas on his residency project publication in IJAA. 👏 to mentors @n_mercuro @KirbyLabMicrobe sciencedirect.com/science/articl…

Congratulations to Dr. Jeannie Lee (@XistHarvard), recipient of IRSF's Innovation Award Grant. This project focuses on restoring MECP2 in patients to potentially treat and cure #Rettsyndrome. More on research: buff.ly/3Ye0Qed #GeneTherapy

Plasmid of the Day pMOD3-mWasabi-nat Depositor: @KirbyLabMicrobe Purpose: Bacterial mWasabi promoter trap hubs.la/Q01gmyrY0

Omicron detected just as well by antigen tests as original (WA1) SARS-CoV-2 strain, but Delta not so well, journals.asm.org/doi/10.1128/jc…. Study performed with live, cultured virus (not heat inactivated or gamma irradiated).

I am speaking at 2022 Advancing HIV, STI and Viral Hepatitis Testing Conference. Please check out my talk if you're attending the event! - via #Whova event app

Congratulations to the awardees of our research funding opportunity @BIDMChealth and IDX20! We look forward to following your progress on #COVID19 research. reaganudall.org/news-and-event…

We spent $1.3 billion nytimes.com/2022/02/02/us/… on possibly the poorest performing antigen test (based on data in EUA Instructions for Use). See distribution of detection limits for all approved EUA's. Limit of Detection Matters academic.oup.com/cid/article/73… for COVID antigen tests too!!

We spent $1.3 billion nytimes.com/2022/02/02/us/… on possibly the poorest performing antigen test (based on data in EUA Instructions for Use). See distribution of detection limits for all approved EUA's. Limit of Detection Matters academic.oup.com/cid/article/73… for COVID antigen tests too!!

What is a Protein? (from PDB-101) youtu.be/wvTv8TqWC48 via @YouTube What a great short video on proteins structure.

From my colleague, Ramy Arnaout, "Visualizing Omicron: COVID-19 Deaths vs. Cases", further enhancements to visualization forthcoming. github.com/rarnaout/Covid…

Our study posted to MedRXiv supports use of SARS-CoV-2 antigen tests to predict infectivity at the time of testing: medrxiv.org/content/10.110…

From my research lab manager on supply chain: “Just got the gel loading tips that I ordered 1 year + 4 days ago.  I put them on the metro shelf in the lab on one of the middle shelves.” At least they remembered us!!!