Interfacial Cell Biology

Thanks for everyone contributing!

We are hiring a PhD @EdinburghUni @SchoolOfEng_UoE to work on the bottom-up design and construction of synthetic cells using #microfluidics and #lipid membranes. Lab is based at the Institute for Bioengineering. #synbio eng.ed.ac.uk/studying/degre… Please RT!

We have a PhD position available to study neuronal functions of autophagy and endocytosis.

#Job alert! A #postdoc position in my lab @CECAD_ @UniCologne is open until December 1st. We look for: enthusiasm, curiosity, scientific rigour, and a background in protein quality control, lysosome signalling, or the cell cycle. We offer: fully funded position, top European research campus, state-of-the-art facilities, collaborative working environment, interdisciplinary approach, fascinating and understudied cell model. Details: jobportal.uni-koeln.de/ausschreibung/… Applications *ONLY* here: jobportal.uni-koeln.de/bewerben/1859 Interviews of shortlisted candidates will be scheduled after December 1st. Please spread the voice, share & RT. Thanks!

Thanks to the team and for funds: @SPP2191 @dfg_public! Cell membranes shaped and cut by phase-separated liquid protein condensates nature.com/articles/d4158… @Pha_Tran_Papers

Gratuliere, Suze!!

We simulated the formation of OPTN droplets on the membrane in mitophagy. The droplets could lead to the membrane connection. Autophagy adaptors mediate Parkin-dependent mitophagy by forming sheet-like liquid condensates | The EMBO Journal embopress.org/doi/full/10.10…

Exciting news: 2D condensates at mitochondria! Thanks to @yj_sakai, @ChinoHaruka, @MizLabUT. Autophagy adaptors mediate Parkin-dependent mitophagy by forming sheet-like liquid condensates | The EMBO Journal embopress.org/doi/full/10.10… @Pha_Tran_Papers

💧✂️Liquid droplets cut membranes without protein scissors🌱 A study led by @knorrlab and team shows that tiny liquid droplets, known as biomolecular condensates, cut membranes of plant cells without the need for specialized protein✂️ Read more 🔗 uni.koeln/RRD22

✂️A *liquid* pair of scissors? This is DALL-E's representation... But biology has built the real deal, as our new work w/ @XiaofengFangLab @KnorrLab @aland_lab just out @Nature shows nature.com/articles/s4158… (1/6)

@Ella_Maru @aland_lab @Nature @AgudoCanalejo @XiaofengFangLab @csbdresden I think that cells harness this alternative membrane fission process and sure, this process should be manipulable

@aland_lab @Nature @AgudoCanalejo @XiaofengFangLab @KnorrLab @csbdresden Could this condensate-induced mechanism be harnessed to manipulate intracellular trafficking processes?

Condensates can not only bend biomembranes, but also cut them (fission). Check out the first evidence in our @nature paper: t.ly/qOkcX Great collaboration between maths, physics and biology @AgudoCanalejo @XiaofengFangLab @KnorrLab @csbdresden

Not exactly X-less

In intracellular trafficking, the ESCRT machinery mediates membrane scission of the multivesicular bodies (MVBs). Work @nature proposes that, in plant cells, this is mediated by biomolecular condensates, and depends on the condensates' physical properties. nature.com/articles/s4158…

We are thrilled to welcome our new colleague Roland Knorr with his team @KnorrLab who just was appointed as W2 professor @BCCologne @UniCologne @UKKoeln We are looking forward to exciting research on phase separation & shaping of biological membranes biochemie-med.uni-koeln.de/en/forschung/a…

Exciting news: our lab expands and moves @UniCologne next to @CECAD_ ; thrilling papers will be out soon...

Looking to join our lab in #berlin? We're hiring! #microscopy #imaging #biology #physics #biophysics #biochemistry #cellBiology #Bioengineering #phdstudent #studentships #PhDposition #postdoctoral #Postdocposition #sciencejobs #postdoc @BioCondensates @dfg_public @HumboldtUni

❗️just out @PhysRevLett ❗️a surprising nonequilibrium effect hidden in a classic theory of phase separation...

Our new preprint is out! The standard shapes of phagophores during autophagosome formation are statistically determined by 3d-EM and are quantitatively explained by a physical model. Congratulations, Yuji!!biorxiv.org/content/10.110…

"We can't change our city. We are not Amsterdam!" #Vienna: 'hold my #Weisswein🥂*' - Königsegggasse (*or 16er-Blech🥫 if you prefer)

みとこんどりゃ旨し　#紅芋タルト