Korkhov Lab

The @KorkhovLab has an opening for a student or a scientist displaced from Ukraine. If you are interested or know someone who might be interested - please DM.

Our study on the lipid dependence of Cx32 gap junction channel conformations is now out in @NatureComms. Amazing work by @PLavriha, @FluriCarina, and Jorge Hernández González! nature.com/articles/s4146…

Our manuscript on the distinct mechanisms by which drug-like small molecules target the malaria parasite transporter PfNCR1 is now on bioRxiv 👇 biorxiv.org/content/10.110…

Our manuscript exploring the radiation dose effects on protein structure is now online, underscoring the great promise of correlative workflows combining X‑ray tomography with cryo‑EM at high resolution 👇 biorxiv.org/content/10.110…

In collaboration with the Posthaus Lab, we identify ANTXR2—also the anthrax toxin receptor—as the receptor for Clostridium perfringens NetF pore forming toxin. Cryo-EM shows extensive contact between the pore and the receptor #Microbiology #CryoEM doi.org/10.1101/2025.0…

Our investigation of lipid dependence of Cx32 gap junction channel conformations is now online on @biorxivpreprint. Great work by @PLavriha, @FluriCarina and Jorge Hernández González! biorxiv.org/content/10.110…

#Authorinterview: Basavraj Khanppnavar a structural biologist and biochemist talks about his work on "Molecular Snapshots Unravel Botox’s Secrets of Nerve Cell Entry". #botox #cryoEM #neuron @BasurajSK @KorkhovLab @ETH_en biopatrika.com/academia/resea… via @biopatrika

Happy to share our latest publication on @NatureSMB Natural Structure & Molecular Biology, we show tau filaments show Alzheimer fold in mutants V337M and R406W. nature.com/articles/s4159… nature.com/articles/s4159… thanks @SjorsScheres and @MichelGoed support 🥳🥳🥳

Want to know “How does #Botox enter neuronal cells at the right time & place to exert its #therapeutic effect?” Check out our latest paper @NatureComms @psich_en @eth_en @ETH_DBIOL @KorkhovLab.nature.com/articles/s4146…

Our joint study led by @BasurajSK and Oneda Leka, on the interactions between botulinum neurotoxin BoNT/A1 and its receptor SV2B, is now out in @NatureComms. This was a great collaboration with the group of Richard Kammerer (@psich_en)! rdcu.be/d9rOL

Excited to share that I've been elected as member of the "Junge Kolleg" of the Nordrhein-Westfalian Academy of Sciences and Arts. I'm honored to have this opportunity to serve the community! Here's the link to the announcement, unfortunately only in German awk.nrw/news/nachwuchs…

@vercellino_ire @SachseGroup Congratulations Irene!

Honored to have received the #ForWomenInScience #FWIS2024 award. Thanks to #Loreal #LorealGroup #UNESCO, the selection committee, the organizers of the amazing ceremony and to my family that supports me doing science! #StopTheDropout #EqualOpportunity #WomenEmpowerment

Authors from @Gschertler lab, @psich_en report structures of an activated bistable opsin, a bidirectional photoswitch. nature.com/articles/s4146…

Captain Aureispira - a bacterial pirate ship🦜🏴‍☠️🪝- boarded @ScienceMagazine. Check out the manuscript here: science.org/doi/10.1126/sc… and have a look on our extended thread below ⬇️We provide new insights on bacterial predation from molecules ⚛️to ocean samples 🌊

CryoEM structure of the human Connexin-43 gap junction channel (PDB code: 8QKO) #scivis #molecularart #sciart @dzine_ai @proteinimaging behance.net/gallery/209149…

Our work on the regulation of the gamma-tubulin ring complex is now online @Dev_Cell! Huge congratulations to all co-authors involved! Open access link to the paper: cell.com/developmental-…

The gamma-tubulin ring complex controls microtubule nucleation in cells. The @MikeVVieczorek lab demonstrates that CDK5RAP2 regulates the structure of the gamma-tubulin ring complex to dramatically promote its microtubule-nucleating activity. More: biol.ethz.ch/en/news-and-ev…

The IBMM wishes to host an SNSF Starting Grantee! If you are into membrane biology, and would like to start your lab in our institute at Uni Bern, please check the details and apply: ohws.prospective.ch/public/v1/jobs…

Olga Polotska, Director of the @NRFUkraine, is delighted by the success of the joint call for proposals with the SNSF. The research projects are proof of “how diverse #research in #Ukraine continues to be, despite all the difficulties.” ➡️ sohub.io/zr51

The paper by @BasurajSK, @KorkhovLab, the group of @arshukla (@IITKanpur) and other collaborators now published in @CellCellPress provides insights into the mechanism of chemokine interactions with the Duffy antigen receptor DARC. Full paper 👉 brnw.ch/21wLLZS