Lisa-Marie Legault

107 posts

Lisa-Marie Legault banner
Lisa-Marie Legault

Lisa-Marie Legault

@LM_Legault

PhD student. Working on epigenetic, embryonic development and FASD. Outdoor lover and chocolate addicted.

Katılım Şubat 2017
234 Takip Edilen146 Takipçiler
Lisa-Marie Legault retweetledi
Lisa-Marie Legault
Lisa-Marie Legault@LM_Legault·
Latest paper is now out! This one might be even more special as it is my last PhD paper. Thanks to all the co-authors & @McGraw_Lab thanks for everything. I was lucky to spend my years as a graduate student in such a stimulating environment, with an amazing team and involved PI.
Serge McGraw@McGraw_Lab

Paper alert! @LM_Legault et. al show that preimplantation alcohol exposure alters the #DNAmethylation and transcriptomic profiles in mouse placentas in a sex-specific manner, with DNA methylation being a robust predictive signature. bit.ly/4egTNcZ @CR_CHUSJ #FASD

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Ariane Lismer
Ariane Lismer@arianelismer·
The product of a large and exciting international collaboration! Our study investigating the consequences of the endocrine disruptors DDT/ DDE on the sperm epigenome of Greenlandic Inuit and South African VhaVenda men is finally out. ehp.niehs.nih.gov/doi/10.1289/EH…
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Serge McGraw
Serge McGraw@McGraw_Lab·
Congratulations, Dr. Lisa-Marie Legault (@LM_Legault)...Ph.D.! What an extraordinary journey it has been! Your accomplishments are truly exceptional, and we wish you the best in your future endeavours. Thank you for everything, you will be greatly missed. @CR_CHUSJ @UMontreal
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Lisa-Marie Legault retweetledi
Canadian Epigenetics
Canadian Epigenetics@CEEHRC·
And that's a wrap on #CanEpi23! Thank you to everyone who attended and all of the sponsors for their continued support of our meeting. We've enjoyed seeing all of the amazing science and wonderful interactions that have taken place over the last 3 days. See you all in 2024!
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Serge McGraw
Serge McGraw@McGraw_Lab·
Explore our latest @Preprints_org review aiming to highlight O-GlcNAcylation's central role as an epigenetic mark, focusing on histone modifications. Collaboration with Thomas Dupas (new postdoc in our lab) and Prof. Benjamin Lauzier (@NantesUniv France ) preprints.org/manuscript/202…
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Serge McGraw
Serge McGraw@McGraw_Lab·
Our News and Views ―Inheritance of epigenetic DNA marks studied in new mouse model― of the Takahashi et al. Cell 2023 paper on the Transgenerational inheritance of acquired epigenetic signatures at CpG islands in mice. Fun collaboration with @KimminsSarah nature.com/articles/d4158…
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Professor Sarah Kimmins
Professor Sarah Kimmins@KimminsSarah·
Congratulations to Kimmins lab PhD graduate Dr. Anne-Sophie Pépin! Her thesis research on paternal epigenetic transmission of metabolic disease uncovered a role for sperm histone H3K4me and paternal effects of the placenta as novel routes to developmental origins of disease.
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Lisa-Marie Legault retweetledi
Serge McGraw
Serge McGraw@McGraw_Lab·
Happy to share our study in @FASEBorg ! Using a mouse model of pre-implantation alcohol exposure, we show that a maternal enriched diet for methyl-donor mitigates the negative impacts of alcohol exposure. #FASD bit.ly/3LcatGS
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