Schneeberger lab

🌾 We have an open postdoc position in Plant Genomics in our group at HHU Düsseldorf! If you enjoy plant genomics, asking big questions, and the satisfaction of code working on the first try, check out schneebergerlab.org/career/ Apply by Mar. 31 | 3-year postdoc | German required

🌱 Postdoc position in Plant Genomics/Bioinformatics! Love genome plasticity, computational methods, and solving big questions in plant biology? Join our Institute for Crop Biology at HHU Düsseldorf. More info on schneebergerlab.org/career/ Apply by Nov. 30 | 3-year position

1/ 🚨 My first PhD preprint is out on bioRxiv! We show how tiny mutations—point mutations and kb-level indels—can shape the massive structure of Arabidopsis centromeres. 📄 Read it here: doi.org/10.1101/2025.0… 🧵 A short thread 👇

Interested in hearing more about the story behind our latest paper? Check out our blog post and the latest @NaturePodcast episode! 📝 go.nature.com/3G73vT7 🎙️ nature.com/articles/d4158…

🌱 This resource provides a foundation for genomics-assisted breeding in this challenging autotetraploid crop that feeds over a billion people globally, with particular utility for complex traits governed by multiple loci across different haplotypes! 7/7

🍟 We demonstrate this by generating megabase-scale pseudo-genome assemblies for modern cultivars using only cost-effective short reads - including for 'Russet Burbank', THE famous French Fries potato! 6/7

📢 Excited to share our work out now in @Nature! 📢 We present the phased pan-genome of the European tetraploid potato, based on 10 historical cultivars representing 85% of European potato diversity. Learn more below! 🔗 nature.com/articles/s4158… 1/7

Thrilled 😻 😁💃🏾 to share the final version of our manuscript on Luzula holocentromeres now in @NatureComms. Great collaborations during this project 🙌🏾💪🏾. nature.com/articles/s4146…

Very excited to share the first preprint from my work in @LabSchneeberger! We developed single nucleus RNA-sequencing of recombinant haploid gametes as a method for performing rapid expression quantitative trait locus (aka eQTL) analysis. biorxiv.org/content/10.110… A 🧵 1/N

Our snRNA-seq method combined with eQTL mapping, is powerful & cost-effective, paving the way for advanced gene interaction studies and crop improvement strategies.🌾#Bioinformatics

🔍By capturing mature sperm nuclei, we fine-mapped trans-eQTL hotspots and detected meiotic recombination events. Our study with 5 A. thaliana F1 hybrids reveals that most eQTLs are cell-type specific. Notably, PSV1 regulates sperm nuclei-specific genes 🌿🔬#Genomics #Arabidopsis

🧬Excited to share our latest pre-print! We've developed a rapid eQTL analysis approach using single-cell/nucleus RNA sequencing of Arabidopsis pollen nuclei. This method uncovers cis- & trans-eQTLs, including a master regulator of sperm cell development! 🌱📊 #PlantScience #eQTL

Huge shoutout to all the authors @itsmanishgoel, José A. Campoy, @Zukunftsmusiker, @lisa7cristina, @anshupa_sahu, @hequan_sun, Birgit Walkemeier, @MagdalenaMarek_, Randy Beaudry, David Ruiz, Bruno Huettel @LMU_Muenchen  @maxplanckpress

🧬 The high load of layer-specific mutations often goes unnoticed in bulk analyses. This study provides a holistic view of how these mutations accumulate and propagate, offering new insights into plant genomic architecture. #GeneticResearch #PlantBiology

🧵🌳 Our new manuscript is out! We explored how somatic mutations in trees spread and propagate through different layers of the plant, improving our understanding of the genetic underpinnings of plant growth and diversity. #PlantScience #Genomics doi.org/10.1186/s13059…