LaNoReC Study

Exciting news! The LaNoReC protocol has been officially published in BMJ Open! Huge thanks to all collaborators for their dedication. Read the article: bmjopen.bmj.com/content/14/10/… #RectalCancer #Research #BMJOpen #LaNoReC

First patient recruited to the @LanorecStudy. Nice work @drtfitz_littleT!

On 21-11 Tania Sluckin obtained her doctoral degree by defending her thesis entitled "lateral lymph nodes in rectal cancer". This thesis stresses the importance of adequate treatment of lateral lymph nodes and the LaNoReC trial. Want to receive a PDF? Mail lanorec@amsterdamumc.nl

Lateral lymph nodes during the @ESSOnews 142 conference! On Thursday 26th of October the prognostic implications of the number of lateral lymph nodes and their malignant features were discussed.

The LaNoReC is currently recruiting in 13 centers and the first 7 patients have been included in the main arm, and another 5 patients have been included in the registration arm! Want to join? Mail: Lanorec@amsterdamumc.nl

Neoadjuvant (C)RT is essential for those with enlarged LLNs. Expert radiologists have renewed the LPRGE guideline, and will discuss this guideline in a training sessions with a training case on the 24th of November at 08.00 (UTC+1). Interested? Mail: lanorec@amsterdamumc.nl

New evidence regarding the increased risk at lateral local recurrence for enlarged lateral lymph nodes in rectal cancer patients, don’t rely on restaging size for LLND indication! journals.lww.com/dcrjournal/abs…

Publication alert: node picking or partial LLND do not decrease lateral recurrence risk in rectal cancer patients with enlarged nodes. In the LaNoReC these patients undergo a complete LLND aiming to lower the risk to <6% pubmed.ncbi.nlm.nih.gov/37340200/ #SoMe4Surgery #rectalcancerresearch

The renewed Dutch delineation guideline has been approved by the Dutch GI radiotherapy association (LPRGE)! This guideline will guarantee uniform delineation and coverage of lateral lymph nodes in the LaNoReC study. Want to join the next online training? lanorec@amsterdamumc.nl

Since the hands-on cadaver session in 2021, monthly proctoring sessions have been implemented to provide feedback and guarantee uniform dissection. Last months the do’s and don’ts of LLND surgery were discussed. #colorectalsurgery #LLND #improvement

Adequate coverage of lateral lymph nodes by routine radiotherapy is associated with considerable lateral local recurrence risk. Published in #RedJournal #laterallymphnodes #colorectalresearch #radiotherapy @TaniaSluckin @SanneHazen @MirandaKusters sciencedirect.com/science/articl…

Update @LaNoReCstudy: the study has become a registration study, not subject to ethical restrictions, open for ALL patients with enlarged (≥7.0mm) or intermediate (5.0-6.9mm) lateral nodes with ANY neoadjuvant treatment, with a new protocol. Keen to join? lanorec@amsterdamumc.nl

Join us for the first colorectal plenary of #RACS23 in Hall A. East meets West, a story of lateral nodes by James Ngu.

Inspirational start to colorectal section at #RACS23 with masterclass on lateral lymph node dissection with @HiddeKroon @MirandaKusters and James Ngu. Great program from @tarik_sammour & Tiong Sia

Dr James Ngu delivers incredible technical talk on Lateral Pelvic Node Dissection for rectal cancer, complete with origami anatomy lesson! #RACS23

.@HiddeKroon gives a bleeding edge update on management of LPLND in rectal cancer. #RACS23 @RACSurgeons

15 to 20% local recurrence rate if lateral nodes > 7mm are left behind after CRTx for rectal cancer. @MirandaKusters Significantly lower if dissected. Response to CRTx may not be enough. #RACS23

Vacature PhD kandidaat: per 1 juni 2022 zoeken wij een enthousiaste basis-arts om onze team te versterken! Je gaat aan de slag met de grootste landelijke Snapshot studie over rectumcarcinoom en het opstarten van de LaNoReC studie. Interesse? Mail: s.hazen@amsterdamumc.nl

A great first LLND training day at the Amsterdam Skills Centre with 17 Dutch LLND surgeons: expert presentations, hands-on cadaver sessions and online proctoring by prof. Tsuyoshi Konishi, MD Anderson #colorectalsurgery #laterallymphnodes #some4surgery #colorectalresearch

Post 2/2 (see previous post): What would you do next in this case? The LLN is still 4mm on the second restaging MRI with a cCR of the primary tumor... #some4surgery #colorectalresearch #laterallymphnodes #colorectalsurgery