Check out our work on RNA structure in introns! Testing >100k base pairing variants, we found that RNA structure can predictably tune gene expression. Just by changing intron sequence, we see a dynamic range of regulation comparable to messing e.g. with promoters.
biorxiv_biochem@biorxiv_biochem
Control of gene output by intron RNA structure biorxiv.org/content/10.110… #biorxiv_biochem
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