Lowe Lab

We are grateful to for support from @MSKCancerCenter @hhmi_science @TheMarkFdn @GBeene_MSK

Congrats to authors @Clemens2Hinterl @hailgol #DMH @vBarthet @Aveline_Filliol !

🚨 Just out from our lab in @cellbycellpress - a comprehensive review of cellular senescence, part of the special issue celebrating the Hallmarks of Cancer cell.com/cell/fulltext/… 🚀

We are grateful for support from @TheMarkFdn, @MSKCancerCenter #TDF and #ETC, @DamonRunyon, #FoundationforWomensCancer, #GlennFoundation, @NIH and @hhmi_science

& huge shoutout to lead author @ZedaZhang for recently being selected for the @sitcancer 2026 Sparkathon Distinguished Investigator Award and the 2026 @AACR Barbara Campbell Creighton Award!

Excited to share our latest work, out now in @CellCellPress! Led by @ZedaZhang, we uncover a convergent uPAR⁺ tumor ecosystem that creates broad vulnerability to CAR T cell therapy. A collaborative effort with @Michel_Sadelain and @Aveline_Filliol. cell.com/cell/fulltext/…

Now accepting applications for our 2026 Cancer Biology & Cancer Engineering programs. Aspiring scientists & engineers will solve fundamental problems in biology & conduct research & develop technology that will help understand, diagnose, & treat cancer. bit.ly/3WUiuo1

And a HUGE shoutout to lead author @almudena_Chaves for recently receiving the prestigious Eddie Méndez Scholar Award! 🚀🌟bit.ly/4lmNLuM

Excited to share our latest work out now in print @Nature! Lead by @almudena_Chaves and @ScottMillman_MD, we uncover how metabolic rewiring via OGDH controls tissue regeneration and stem cell fate in the intestine 🚀🚨 bit.ly/44oaOiW

We thank all our collaborators, @dana_peer, @lydfinley, Justin Cross, Craig Thompson @MSKCancerCenter & all members of the @LoweLabMSKCC involved in the project. & special thanks to Nav Chandel and Ram Chakrabarty for a News and Views about our work! ⭐️ bit.ly/4eHeD6h

Enjoying another day of great science and great company at #AACR25 with Lowe lab alums #LarsZender, #JosefLeibold, and @ktsanov!

@CD_AACR Led by Caroline Broderick and @r_mezzadra, in collaboration with Revolution Medicines and Mallika Singh. Check it out!

Out now in @CD_AACR and featured #AACR25, we show a combinatorial approach to overcome resistance to RAS(ON) inhibitor monotherapy in PDAC, where use of CDK4/6 inhibitor Palbociclib and CD40 agonist drives therapy-induced senescence & CD4 T cell-dependent tumor-immune equilibrium

After a pandemic-triggered hiatus, the 'Lowe riders' are back to support @Cycle4Survival, an event hosted by @Equinox where teams cycle to raise funds for rare cancer research at MSKCC. Please consider supporting our team at the link below!👇 tinyurl.com/4xuxdnmm

Scott was part of a mini Lowe lab reunion at the recent #AMC25 @Fusion_Conf in the Dominican Republic. Great to see former trainees @dow_lab, Chong Chen, Kiki Liu, and honorary lab member @LeilaAkkari1 doing well!

Thrilled to share the news that lab alums @DirenaAC and @SoftSarcoma have received @ERC_Research Consolidator Grants! Well deserved recognition for great scientists! 🚀⭐️

Had a great time visiting MIT as part of the @kochinstitute 50th anniversary seminar series! Always fun to be back visiting former mentors and trainees!

The @LoweLabMSKCC is participating in @Cycle4Survival to raise money for rare cancer research at @MSKCancerCenter! No amount is too small. Click the link to donate and learn more. Thanks!! secure2.convio.net/mskcc/site/TR?…