Dylan Burnette

I am excited to finally be able to share with you our work reporting the first Extracellular Vesicle with a personality! This video does not show a cell, it is a Blebbisome! #CellBiology nature.com/articles/s4155…

The inside of a heart muscle cell photographed with an electron microscope. The powerhouses/overlords of the cell, mitochondria, are shown in pink. The repeating structures are the basic units of contraction that drive each heart beat (i.e., sarcomeres). #CellBiology

The heart of a zebrafish embryo photographed through a microscope. (Ventricle: Left; Atrium: Right). The nuclei of both the heart cells and blood cells are shown. "What? Red blood cells do not have nuclei!", you say. So human centric of you...... #CellBiology

Immature heart muscle cells photographed through a microscope. Nuclei (yellow/green) and the molecular motor driving muscle contraction, myosin II (purple/blue), are shown. #CellBiology

Burnette Lab 2026 #CellBiology

Neuronal growth cones at the end of neurites (immature neural extensions that have yet to turn into axons or dendrites) videoed through a microscope. #CellBiology

Cells photographed through a microscope. #CellBiology

Cover image for "The microtubule GTP-tubulin cap size is modulated during cell division" by Anna Cassidy! I know it says "May 1, 2026", but it is already online so here it is! molbiolcell.org/doi/10.1091/mb…

@Pablosquest Not an animation or AI. This is a time-lapse from a confocal microscope where a DNA binding protein, an actin binding protein, and a mitochondrial protein were fused to fluorescent proteins. Of course, each original grayscale channel was pseudo-colored to make this overlay.

@MAG2ART Animation

A cell videoed through a microscope. DNA in the nucleus (cyan), mitochondria (yellow), and the actin filament cytoskeleton (magenta) are shown. #CellBiology

@hermetictrader1 The mitochondria are moved. Molecular motors walking on microtubules and actin filaments (e.g., kinesin and myosin, respectfully) pull on the mitochondria to move them around the cell.

@MAG2ART Every time that you shows the mitochondria's performance moving like little slugs... It seems like self-induction dynamics. Do they move on their own or are they moved?

A cell going through cell division to create two daughter cells videoed through a spinning disk confocal microscope. DNA (red), Golgi apparatus (green), actin filaments (blue) are shown. #CellBiology

@cohenlaboratory Thank you!

@MAG2ART felixcampelo.wixsite.com/membranetraffi…

Are there still Zoom-based scientific seminar series? As I plan for a promotion cycle that expects ~10 invited talks/year. I love giving talks and talking with interesting scientists, just not the travel part. I study the growth and function of the heart and large EVs.

A cancer cell videoed through a microscope. It has 3 nuclei (magenta). The powerhouse/overlords of the cell, mitochondria, are also shown (green). #CellBiology

Two cells isolated from a fish scale videoed through a DIC microscope. The cells are cool but now all I see are extracellular vesicles floating by in the media and stuck to the substrate....... #CellBiology

This is not a dispute over nomenclature. The authors of the zombosome paper misrepresented our published data to justify introducing a new name. Whether intentional or unintentional, this misrepresentation should have not made it past peer review. nature.com/articles/s4155…

They renamed blebbisomes. The authors claimed erroneously in their paper that blebbisomes are found only in cancer cells, whereas we clearly demonstrated that blebbisomes are produced by normal cells. The structures described here are simply blebbisomes generated by astrocytes.

@Tabdanov I think certain micropatterns would inspire the cells to produce more blebbisomes. It also did not take us long to find a blebbisome being created by a cell within a 3D collagen gel, although we never quantified formation rate. So I would say "probably" to both questions.

@MAG2ART Will these cells generate even more blebbisomes on complex surfaces (micropatterns, nano textures)? In 3D matrices?

Our Blebbisome paper has been out for a year and has 50 citations! To celebrate, here is Video 5 from the paper: fibroblasts (green arrows) and their blebbisomes (magenta arrowheads) hanging out. #CellBiology #microscopy See the paper here: nature.com/articles/s4155…

CELL BODY MICROTUBULES Among other things, microtubules are the tracks used by cells to traffic membranes (e.g., next to the nucleus where the #Golgi resides). It takes super-resolution microscopy to resolve and study this complex microtubule-network (image). #CellBiology