Mahinur Mattohti

Our preprint on epigenome reprogramming in R and NR melanoma patients treated with ICB suggests an enhancer biomarker and BETi+aPD1 combo. Great collaboration with @manoliskellis @gmboland @MMattohti @tangming2005 @JenWargoMD @dliu_ccb @MDAndersonNews biorxiv.org/content/10.110…

Our study on chromatin states in metastatic melanoma came out today. We demonstrate genotype-specific chromatin state patterns and suggest use of PRC2 inhibitors in NRAS-mutant melanoma. cell.com/cell-reports/f… @tangming2005 Chris Terranova Mahinur Maitituoheti @MDAndersonNews

Our manuscript showing tumor suppressor function of KMT2D in melanoma is out today in Cell Reports. Enhancer Reprogramming Confers Dependence on Glycolysis and IGF Signaling in KMT2D Mutant Melanoma cell.com/cell-reports/f…