Dr. Miriam Tschaffon-Müller

@isfrfractures Very impressive presentation given by @EstherWehrle at the #ORS2025. She investigated molecular mechanisms of fracture nonunions by spatial transcriptomics.

@isfrfractures Amazing talk by Morgan Cobban from Trinity College Dublin about GPR161 as a novel osteocyte mechanosensor and regulator of osteoclastogenesis at the #ORS2025 Annual Meeting.

@isfrfractures Great presentation by Dr. Mubashir Ahmad from Ulm university at the #ORS2025 Annual Meeting about how a Wnt1-G177C mutation impairs fracture healing.

Happy new year to all @isfrfractures members! A short throwback to one highlight of 2024: the ORS ISFR/OTA BSFF Joint Meeting in Montréal, Canada was a great success! We saw a lot of wonderful presentations and posters, especially from our awardees:

Many thanks to @isfrfractures for the invitation to present our work about the role of catecholamines in bone/immune crosstalk at the #ISFR2024 and for the podium award for my presentation about the role of Piezo1 in hypertrophic chondrocytes. It was so great to meet you all!

@isfrfractures Comm CTE at #ISFR2024 with @AugustineSaizMD @EvanBuettmann @andreaialford1 @MTschaffon We miss you at: Ramkumar Tiruvannamalai Annamalai, Rodolfo De La Vega, @Madhura0327 @ORSsociety

@isfrfractures Very nice last podium presentation of today's #ISFR2024 meeting by Dr. Kevin Leclerc about the role of the Hox gene Hoxa10 in #bonehealing. @ORSsociety

@isfrfractures Let's continue the findings gained by spacial transcriptomics: Dr. Esther Wehrle presented Dr. Maria Schröder's work about the molecular mechanisms of #fracture nonunions at the #ISFR2024. @ORSsociety

@isfrfractures Another new strategy to improve fracture healing: Tarek Klaylat presented the use of a phosphate-releasing thermoresponsive hydrogel for #fracture treatment at the #ISFR2024. @ORSsociety

@isfrfractures The sclerostin inhibitor Romosozumab is a successful new approach for #osteoporosis treatment. Prof. Dr. Xiaodong Li now presented the use of Romosozumab for improving #bonehealing in critical size defects at ##ISFR2024. @ORSsociety

@isfrfractures Prof. Dr. Matthew Silva presenting the work of Leyi Chen about the novel approach of treating nonunion fractures with an inducible BMP2-lentivirus delivered by cryogel scaffolds at ##ISFR2024. @ORSsociety

@isfrfractures Avani Vaishnav giving an interesting presentation about serum protein indices of normal human #bonehealing at #ISFR2024. @ORSsociety

@isfrfractures Justin King presented at the #ISFR2024 how aging affects periosteal stem/progenitor cells which play an important role during #bonehealing. @ORSsociety

@isfrfractures Very impressive presentation by Prof. Dr. Elisabeth Rosado Balmayor about the use of micro RNAs for the improvement of #bonehealing at #ISFR2024 @ORSsociety

@isfrfractures A lot of patients are suffering from fracture nonunions. Dr. Andrew Harrison gave a great presentaion about Low Intensity Pulsed Ultrasound (LIPUS) as a treatment option for #fracture nonunion. @ORSsociety

@isfrfractures How can we improve the mechanical environment for #bonehealing? Dr. Hannah Daily presented this topic in detail at the #ISFR2024. @ORSsociety

@isfrfractures Very interesting presentation by Dr. Ester Wehrle at #ISFR2024 about understanding the molecular mechanisms how cyclic mechanical loading can improve #bonehealing using spacial transcriptomics. @ORSsociety

@isfrfractures Dr. Emil Schemitsch told us at the #ISFR2024 how important the right fixation is for #bonehealing. @ORSsociety

@isfrfractures Great presentation by Dr. Elise Morgan about the fundamentals of mechanoregulation in #bonehealing at the #ISFR2024. @ORSsociety

Average correlation as an indicator for inseparability, Michael E. N. Tschaffon and Johannes Seiler @mentschaffon @tschoooo @uni_ulm #Quantum #QuantumInformation go.aps.org/3UIu1rd