Manfred S. Weiss

Here is an interesting quote from practicalfragments.blogpsot.com : "By far the biggest winner among methods has been X-ray crystallography; it jumped from sixth place in 2011 to first place in both 2019 and 2024." Yeah!

Where to House Big Data on Small Fragments? | ChemRxiv - go.shr.lc/4j3oXY1

Publications aplenty. 2024 abounded in reviews related to FBLD - structure-based methods, covalent fragment strategies, targets, PROTACs, and more practicalfragments.blogspot.com/2024/12/review… @sa_poulsen @ManfredSWeiss @ACSPublications @nmr900 @DiamondLightSou

Just published in @Structure_CP: A review with contributions from @ManfredSWeiss, detailing the challenges, state-of-the-art and future directions for integrated structural biology at European research infrastructure sites. doi.org/10.1016/j.str.… @HZBde @HZB_BESSY @instructhub

Exiting news: a new publication describing the HZB-MX F2X fragment-screening facility in all aspects is out in @Appl_Research. Read all about our facility here: onlinelibrary.wiley.com/doi/10.1002/ap… Congratulations to @TatjanaBKL, Melanie and the entire F2X-team. @HZBde @HZB_BESSY

And now a contribution from @HzbMxde by Uwe Müller on Trends in macromolecular crystallography at #InSynX

From the ECM34.@ManfredSWeiss

@ManfredSWeiss is at the ECM Meeting in Padova (Italy). @DGK @Swisscrystallog @IUCr2023 @IUCrJ

Out now in @ActaCrystD : A new paper with contributions from @ManfredSWeiss, about crystallographic fragment screening against a protein from Mycobacterium tuberculosis. Read all about it here: doi.org/10.1107/S20597… @HZB_BESSY @HZBde

Hot off the press: a new paper in the European Journal of Medicinal Chemistry, with contributions from @ManfredSWeiss. Read all about the structure-based mapping of the KDM4D binding pocket here: doi.org/10.1016/j.ejme… @HZBde @HZB_BESSY @ELSchemistry

@ManfredSWeiss will be attending the ACA conference in Denver next week. Anybody interested in IUCr-2029 can approach him and get the latest news. @IUCr2023 @DGK @JKYC_DGK @Swisscrystallog

🔔Meeting support available for #EarlyCareerScience Early registration & bursary application deadline for the International School on Fundamental Crystallography 7th MaThCryst School in Latin America >> 24 June 2024! even3.com.pe/e/ISFC2024-7Ma…

🗓️We've updated our logo and our calendar! For more information please refer to the @IUCr website where you can find out about bursaries, abstract deadlines and registration ↓ iucr.org/calendar/calen…

Hot of the press in @ChemMedChem: A new paper with contributions from @ManfredSWeiss and @Jan_Wollenhaupt, featuring data collected at BL 14.2. It describes new Furin inhibitors partly based on fragments, even making front cover! doi.org/10.1002/cmdc.2… @HZBde @HZB_BESSY

Out now, in @ActaCrystD: A new paper from Neumann et al, with contributions from @Jan_Wollenhaupt and @ManfredSWeiss. Read all about it here: doi.org/10.1107/S20597… @HZB_BESSY @HZBde

The #DGKconference in beautiful sunny Bayreuth had 4 days of informative lectures interspersed with fun social evenings bringing people from diverse fields together, ending successfully with a interview with @IUCr by @florian_meurer (Our new Chair🥳) and Tina Weigel (ex-Chair❤️)

Save the date: Wednesday, 24. 04 is the monthly Colloquium by Zoom, organized by @AfSynchrotron (4PM GMT+2) "The problem of protein folding: how it may go wrong and how cellular machines make it go right" by Paolo De Los Rios from @EPFL_en Registration: us02web.zoom.us/meeting/regist…

Everybody, please stop by and pick up your IUCr-2029 badge @Conventus_Jena

Get all the news about IUCr-2029 at the General Assembly tomorrow. Or stop by at the table for a chat.

Manfred Weiss at the IUCr-2029 table at the DGK conference in Bayreuth