Fátima Lessa

🇮🇷 The key to the Strait of Hormuz is in the hands of the soldiers of Tangsiir The commander of the IRGC of Iran, Ahmad Vahidi: The Strait of Hormuz will not open at the tweet of the US president; the management and control of this waterway are in the hands of Iran. Nothing has the right to enter without permission, and in case of violation, it will be considered a legitimate target. The soldiers of Shahid Tangsiir hold the lock of this waterway, and the key to it is only in their possession.

🚨 ATENÇÃO, PESQUISADORES! O MCTI abriu novas chamadas do Programa-Quadro do BRICS, com investimento de R$ 15 milhões para projetos de pesquisa e inovação.

É fácil demais escolher @Haddad_Fernando para governar São Paulo!

🔴North Korean leader Kim Jong Un: "Palestine is not just a matter for Arabs or Muslims, it is a matter of freedom."

Since the Jews are trying to defame Michael Jackson again, here are the facts…. In 1993 Michael Jackson wrote a song called “Palestine Don’t cry.” His Jewish producers (Sony Records) would not let him release it. When was Michael Jackson first accused of child Sex abuse? - 1993. Who accused him? A failed Jewish dentist Evan Chandler. (On behalf of his son.) The Psychiatrist that “interviewed” the young supposed molested boy ? Richard Gardner. Jewish. The press that defamed him? Jewish His sister Latoya Jackson said the allegations were true, only to later in life admit that her Jewish husband was beating her and told her to do it. Michael Jackson was never convicted of any wrongdoing. "They suck they're like leeches," "It's a conspiracy. The Jews do it on purpose." -Michael Jackson

Thiago y Saif vinieron hace unos días a Cuba, para traernos amor y solidaridad… Merecen nuestro apoyo y denuncia… Torturados, secuestrados, apresados por sionistas asesinos de niños… y aún hay quienes callan ante esto o desean ese mismo destino para Cuba. No lo vamos a permitir. ¡Luchar por Cuba es luchar también por los humillados y golpeados del mundo!

🛢️🇮🇷 TRUTH: Iran is now moving millions of barrels crude oil via railway to friendly countries and they move these shipments faster 14days vs 40 days on a ship. Iran is making TONS AND TONS of money at this moment, and the US blockade rendered useless. The Trump Hormuz blockage is isn't working, it FAILED. Once again the Iranians outsmarted the aggressors on the chessboard. THE U.S. WILL NEVER BE ABLE TO STOP IRAN'S OIL EXPORTS! Iran's exceptional rate of adaptation is second to non.

Estudo do World Resources Institute mostra que o desmatamento global caiu 36% em 2025, puxado principalmente pela redução registrada no Brasil. Desde 2023, retomamos políticas ambientais, fortalecemos órgãos de fiscalização e controle e estabelecemos parceria com os municípios em que o problema era mais grave. Como resultado, registramos queda de 50% no desmatamento na Amazônia nos últimos três anos, após aumento expressivo registrado em anos anteriores. Nossa meta é chegar ao desmatamento zero até 2030. Um trabalho que preserva os nossos biomas e que mostra o Brasil como exemplo de preservação ambiental para o mundo.

O mundo atravessa um momento muito difícil e essas tensões chegam até a sua vida. Nesse cenário, o Brasil não precisa de bravateiros, mas de uma liderança experiente, firme e responsável, que saiba dialogar, defender o país e colocar o interesse do povo em primeiro lugar.

🇨🇳 🇮🇷 BREAKING: Iran's Foreign Minister Abbas Araghchi is heading to Beijing today for talks with China's Wang Yi. Official. Confirmed. Focus includes bilateral ties, regional tensions, and the Strait of Hormuz. While the US threatens and blockades, Iran and China are talking. That is the new equation. Empire isolates itself. The rest of the world builds.

Diagnosed with Cancer, Doctors told Pete Sulack he had a 1% survival chance & only 8 months left to live...now he is in FULL REMISSION. Did he use Chemo & Radiation? NO... Instead of surrendering to the standard protocol, he chose to heal with IVERMECTIN & MEBENDAZOLE. 📚 Here’s what the research shows: • Ivermectin crosses the blood-brain barrier, blocks angiogenesis, and modulates immune checkpoints • Mebendazole disrupts microtubule formation in glioblastoma and lung cancer models • Together, they’re being explored in terrain-based cancer models for apoptosis, metabolism, and more Pete used Ivermectin & Mebendazole in a protocol by Ilyes Baghli, stacked with fasting, targeted nutrition, detox, oxygen therapy and faith. And now? He's in full remission. 💡 This isn’t about miracle pills. It’s about rebuilding the terrain so your body can do what it was designed to do. Share your cancer story below & look for the protocol linked as the 1st reply...

🚨 🇻🇪🇺🇲 ÚLTIMA HORA: El juez Alvin Hellerstein fijó una nueva audiencia a Nicolás Maduro para el próximo 30 de junio. El derecho internacional es claro: los jefes de Estado en funciones gozan de inmunidad absoluta. Ignorar esto no es justicia, es piratería judicial.

NEW ARTICLE: RESEARCH: HBOT in CANCER (Hyperbaric Oxygen Therapy) - 2025 Review Paper from Sichuan University, Chengdu, China HIGHLIGHTS: Tumor hypoxia represents a fundamental barrier to effective cancer therapy, driving resistance to chemotherapy, radiotherapy, and immunotherapy while fostering invasion and metastasis Tumors often have bad blood vessels and high oxygen demand, creating hypoxic (low-oxygen) areas inside them. Hypoxia makes cancer cells: More resistant to chemotherapy, radiation, and immunotherapy. Promotes invasion and metastasis via hypoxia-inducible factors (HIFs) Better at surviving in tough conditions. Hyperbaric oxygen therapy (HBOT) involves breathing pure oxygen in a pressurized chamber (usually 1.5–3 times normal air pressure). This dramatically increases the amount of oxygen dissolved in your blood plasma—far more than you get from normal breathing. That extra oxygen can reach deep into tissues that are poorly supplied, including solid tumors HBOT, by substantially increasing dissolved oxygen in plasma, offers a unique approach to reoxygenate tumors and remodel the tumor microenvironment. HBOT MECHANISMS IN CANCER Fundamental mechanism of HBOT is its ability to increase dissolved oxygen, bypassing limitations of hemoglobin-bound oxygen transport, allowing oxygen to diffuse into deep tissues, reaching hypoxic tumor regions inaccessible to RBCs HBOT can rapidly elevate intratumoral oxygen levels HBOT + Chemotherapy tumor extracellular matrix (ECM) is made of a tightly interwoven network of collagen fibers, which makes it difficult for chemo drugs to reach the hypoxic tumor core, preventing effective elimination of aggressive tumor cells within dense ECM and high interstitial fluid pressure (IFP) in tumor tissues limit the penetration depth of anticancer drugs to typically only 3–5 cell diameters This structural barrier is a major obstacle to drug delivery into tumors HBOT inhibits HIF-1 which reduces collagen deposition and interstitial fluid pressure, thereby increasing chemo drug delivery efficiency HBOT also inhibits HQ1 to induce ferroptosis, enhancing chemo effectiveness Sarcoma study: HBOT alone did not significantly affect tumor size, but the combination of HBOT and 5-FU significantly slowed tumor growth compared to both the control group and the group treated with 5-FU alone HBOT + Radiotherapy HBOT, when combined with radiotherapy, can play two critical roles: 1. acting as a sensitizer to enhance cytotoxic effect of ionizing radiation on tumor cells 2. serving as a therapeutic agent to mitigate late radiation-induced tissue damage HBOT combined with whole brain radiation therapy in patients with solitary brain metastasis improved response rate from 67% to 95%. HBOT combined with IMRT (intensity-modulated radiotherapy) and chemo for glioblastoma increased survival (2y survival 46%, median survival 22mo) HBOT has been shown to alleviate late radiation toxicity (LRT) in breast cancer patients, including the mitigation of fibrosis and pain HBOT also treats radiation-induced cystitis, improving bladder tissue repair and reducing hematuria and urgency symptoms HBOT + Immunotherapy Immunotherapy has shown great promise in cancer treatment, but its effectiveness in solid tumors remains severely limited by the tumor microenvironment, particularly hypoxia Hypoxia is immunosuppressive Hypoxic nature of the solid tumor microenvironment poses a significant barrier to the effectiveness of both CAR-T and Immune Checkpoint therapies Some patients also develop resistance to CAR-T Therapy or Immune Checkpoint inhibitors like Keytruda, Opdivo low-oxygen conditions inhibit CAR-T cell proliferation, differentiation, and cytokine release, thereby substantially reducing their anti-tumor activity in solid tumors In head and neck squamous cell carcinoma (HNSCC), hypoxia-induced immunosuppressive effects significantly increase resistance to anti-PD-1 antibodies (Keytruda, Opdivo) hypoxia leads to metabolic reprogramming in tumor cells, increasing oxidative metabolism and exacerbating intratumoral hypoxia. This ultimately reduces CD8 + T cell infiltration, thereby diminishing the efficacy of PD-1 therapy HBOT can effectively reduce the level of hypoxia in solid tumors and improve the immunosuppressive microenvironment, thereby enhancing the anti-tumor efficacy of PD-1 antibodies. In animal studies, HBOT facilitated the delivery of PD-1 antibodies and the infiltration of T cells into the tumor parenchyma, while depleting stromal components such as collagen and fibronectin, thereby attenuating the mechanical barriers within the tumor microenvironment HBOT treatment also induces robust cytotoxic T lymphocyte activity and long-lasting immune memory, effectively preventing tumor recurrence Conclusion: As an adjuvant therapy, HBOT improves intratumoral hypoxia and synergizes with CAR-T Therapy, as well as immune checkpoint blockade (ICB) to enhance anti-tumor immune responses. MECHANISM OF HBOT IN TUMOR REGULATION: Direct Mechanisms - oxidative stress and DNA damage HBOT sensitizes tumors by elevating reactive oxygen species (ROS) such as superoxide, hydrogen peroxide, and hydroxyl radicals HBOT enhances chemotherapy efficacy by increasing oxygen availability and thereby amplifying oxidative stress Many cytotoxic drugs (like chemo) act through ROS generation, which induces DNA damage and cell death via apoptosis Indirect Mechanisms - tumor microenvironment, angiogenesis, immune regulation TUMOR MICROENVIRONMENT As tumors are rapidly proliferating and metabolically active tissues, their demand for oxygen and nutrients far exceeds that of normal tissues. In the early stages of tumor development, due to a lack of vascular support, tumors sustain their growth by diffusely absorbing resources from the surrounding tissues. However, when the tumor volume exceeds 1–2 mm³ , insufficient resource supply leads to the formation of a microenvironment characterized by hypoxia, ischemia, acidosis, and high interstitial pressure. This condition prompts the tumor to release various growth factors and cytokines, which activate endothelial cells, fibroblasts, and immune cells, thereby promoting the formation of blood vessels and lymphatic vessels. The pathological vascular structures within tumors are often characterized by capillary dilation, basement membrane disruption, and extracellular matrix remodeling. These abnormalities facilitate tumor proliferation, invasion, and metastasis. tumor microenvironment (TME) refers to the complex cellular ecosystem surrounding Cancer Stem Cells - it includes surrounding immune cells, blood vessels, Extracellular Matrix, fibroblasts, lymphocytes, bone marrow-derived inflammatory cells, and signaling molecules Cancer stem cells represent only a small fraction of total tumor mass but are major drivers of tumor initiation, progression, drug resistance, metastasis and recurrence. Formation and maintenance of Cancer Stem cells largely depend on Tumor Microenvironment (!!) Tumor hypoxia plays a crucial role in promoting Cancer Stem Cell formation through the hypoxia-inducible factor (HIF) signaling pathway In one study, researchers eliminated Cancer Stem Cells from two tumors: Triple Negative Breast Cancer, Pancreatic Ca, by combining HBOT with conventional. HBOT, by alleviating intratumoral hypoxia, suppressed Cancer Stem Cell formation and the associated tumor metastasis. ANGIOGENESIS Tumor cells exhibit continuous division and abnormal proliferation, a process that consumes large amounts of oxygen and nutrients During the early stages of solid tumor development, tumor tissues can acquire oxygen and nutrients through simple diffusion. However, once the tumor exceeds a critical size, diffusion becomes insufficient Cancer cells in the central region of the tumor become trapped in a microenvironment characterized by nutrient deprivation and hypoxia to cope, tumor cells activate a series of adaptive response mechanisms, including the upregulation of pro-angiogenic factors such as vascular endothelial growth factor (VEGF) and platelet-derived growth factor (PDGF) Tumor cells gradually acquire more aggressive phenotypic traits As tumor continues to grow, formation of new blood vessels becomes essential for ensuring sufficient oxygen and nutrient supply. This angiogenic process marks the transition of the tumor into a phase of rapid progression HBOT therapy can deplete excessive extracellular matrix components, such as collagen and fibronectin, thereby promoting the normalization of tumor vascular structure and function CONCLUSION: HBOT alleviates tumor hypoxia and enhances the success of chemotherapy, radiotherapy and immunotherapy

Bloomberg: China's unprecedented move against US sanctions against Iran has provoked the risk of a major confrontation 🔻 Unlike its previous practice, when it tried to circumvent US sanctions informally or through intermediaries, China has now officially declared that it does not recognize unilateral US sanctions against third countries (such as Iran or Russia) and has taken its trade with them to an unprecedented level. 🔻 The US administration has threatened to impose "secondary sanctions" against Chinese banks. However, sanctions against major Chinese banks could cause a large-scale shock in global financial markets and disrupt global supply chains. 🔻 This move by Beijing is no longer just a trade rivalry, but a "financial Cold War" aimed at weakening the dollar's hegemony. 🔻 According to Bloomberg, the world has reached a point where the US sanctions tool is facing its most serious challenge since the Second World War. 🔻 If Washington backs down, the sanctions mechanism could be weakened forever, and in the case of tough measures, there is a risk of a complete breakdown of the global economic system.

Presidente LULA no Salão Internacional Automóvel celebra a retomada da indústria automotiva brasileira, que ficou parada durante os quatro anos do desgoverno Bolsonaro. LULA REELEITO

Não é engraçado, é assustador. O Brasil Paralelo devia ser derrubado. Já devia ter sido derrubado faz tempo. Eles são uma máquina de alienar pessoas, uma máquina de produzir ódio, de esvaziar a mente das pessoas. E eles têm esse poder. Estão reescrevendo a história há anos, com investimento bilionário. Tem gente grande por trás disso. Eles têm assessoria de imprensa que custa milhões. Vocês não têm noção do que é isso. Não é engraçado, é assustador entender qual é o objetivo, qual é o projeto e para que serve o Brasil Paralelo. A gente acha que essas pessoas são malucas? Não, gente. Elas estão sendo lobotomizadas pelo Brasil Paralelo, que deveria ser derrubado para ontem. Isso aqui não é liberdade de imprensa. Isso aqui é produção de alienação em massa. É preocupante o resultado disso e o que isso tem causado nas pessoas. Eu vejo o Brasil Paralelo como um perigo para o Brasil e não sei como as pessoas não entendem o que está acontecendo e o quanto é urgente derrubar essa página.

En Francia, grabaron uno de los contenedores de basura de la cadena alimenticia Carrefour, donde desechan todo tipo de alimentos comestibles para seguir el bucle consumista y no bajar los precios. Mientras más de 2,300 millones de personas en el mundo (29.3%) padecen de hambre, 1300 millones de toneladas de comida producida al año (1/3 del total) es desechada para la especulación de los capitalistas. Asi es como la burguesía capitalista mantiene sus beneficios, especulando con el hambre, porque en el capitalismo el derecho a la alimentación no existe, solo es negocio.

É inacreditável saber que tem brasileiros que aceitaram o Genocídio em Gaza com a desculpa esfarrapada de que Israel estava matando apenas os "terroristas do Hamas". Deus me livre de alimentar o meu coração com tanta maldade!

Dos fármacos antiparasitarios Ivermectina + Mebendazol demuestran un 84% de beneficio clínico en el cáncer a los 6 meses.

former senior CIA agent John Stockwell: "We pumped dozens of stories about Cuban atrocities, rapists. We ran fake photographs that made every paper in the country. It was pure raw false propaganda to create the illusion of Communists eating babies for breakfast." Sound familiar?