Matthew Todd

Most days I love my research group. But there are some days when I *really* love them. #OpenScience #outreach on our lab's windows in central London @School_Pharmacy. Open science is #inclusive, and drug hunters could be walking right here... @O_S_M @MycetOS @OSantibiotics

Riverrun, day 2 #scifoo Check out my activity on Strava: strava.app.link/8iPaY8IYALb

Scenic route in search of toothpaste #scifoo strava.app.link/wQEz6LBdzLb

@mattschap @thesgconline @consciencemeds Awesome to see this, congratulations!

All participants to CACHE #1 who agreed to be de-anonymized were invited to join the overview manuscript. The first of a long series to serve as a resource for future developments in virtual screening workflows. doi.org/10.1101/2024.0… @thesgconline @consciencemeds #compchem

Cycling in to @School_Pharmacy again, first time since COVID. Things that have changed: 1) Lime bikes, flocking like pigeons. 2) 50% of cyclists have ear buds in. If you don't do it in lab, don't do it on the road, people.

Perhaps surprisingly, we had a talk today from @NASA in @School_Pharmacy providing, finally, a chance to wear my old @NASAVoyager T.

This new development in Gordon Square near @UCLChemistry is correct.

Weird wardrobe reversal with @aledmedwards at local @School_Pharmacy pub @SkinnersArms1 @thesgconline

@XinQiu2011 @SheppardTomD @DrZoeWaller @RahmanSZSaleem @thesgconline ...in the protein. We're assuming that, based on predicted behaviour in solution, that that is surprising.

@SheppardTomD @MatToddChem @DrZoeWaller @RahmanSZSaleem @thesgconline Hi, the interesting part is that the product we isolated indicates it is either from mechanism B or C

Are you a computational chemist who loves #orgchem mechanisms? We could use a hand in this #openscience project relevant to new #antiviral molecules. Which mechanism is expected to operate in solution? More details at github.com/StructuralGeno… @RahmanSZSaleem @thesgconline

Taking #openscience contributions to the next level. @WhitgiftSchool1 has provided their talented students, who have successfully made molecules for @MycetOS, with their own cool, branded labcoats. I have to get me one of those. @DNDi #mycetoma #NTDs

@DrZoeWaller @PhrmAlliance When you're done for the day, there's a v good toy shop in Chapel Hill if you need gifties for the home crew. Ali Cat Toys. maps.app.goo.gl/vRTkuBxMGUT58R… Bit of a walk, but there are bars en route.

Todd Cherner starting us off at PharmaAlliance week 2024 at UNC Chapel Hill @PhrmAlliance

@lgamon @jdpereira @O_S_M Thank you @lgamon. Yes, our lab works like this. First thing was doi.org/10.1038/nchem.… then e.g. doi.org/10.1021/acscen…. Spoiler: it's crazy fun. The open source software folks blazed the trail.

@jdpereira Check out @O_S_M via @MatToddChem. They’ve been doing it before it was cool.

I’m going to test drive an idea here. And yes, someone may take it and run with it. And that is ok. So, what if we ran a completely open scientific project? Would it be interesting to share the day to day of how the cookie gets made? Discuss issues, failed experiments?

Seriously long shot, but is anyone running the #baytobreakers race in San Francisco this Sunday, and willing to pick up a bib packet at the race expo (Berkeley or Presidio) for a Brit who is arriving too late to do so..?

@MikeTCook @DrZoeWaller "Holding a steak yet?" my wife texted me during the dinner. Alas, chicken, though good. Next time.

Celebrating the school with our stakeholders @School_Pharmacy @UCLLifeSciences

#GetInvolved with #openscience. We've identified #fluorosulfonyls as favored warhead for #DENV RdRp. Details at github.com/StructuralGeno…. Do you have #fluorosulfonyls? We would love to test them! #antiviral

A combination of biochemical, structural, and modeling studies identifies OSM-S-106 as an exemplar of a new chemical class of species-specific reaction hijacking inhibitors. @MatToddChem #malaria #AntimalariaResearch #DrugDiscovery Read more: #Abs1" target="_blank" rel="nofollow noopener">nature.com/articles/s4146…

Interested in synthesis and synthesis prediction? @s_marsden and I have a PhD studentship that is collaborative with @Exscientia. Enhanced stipend. Open to UK students (and, in competition, to international applicants) phd.leeds.ac.uk/project/1706-d…

Deeply fun to welcome students from @WhitgiftSchool1 to @School_Pharmacy @UCLLifeSciences to analyse samples of a molecule they made for the #openscience drug discovery project @MycetOS We NMR'd, we mass specced, we figured it out. ucl.ac.uk/pharmacy/news/… @ResearchInSch

@aledmedwards Nice way to have spelt time.

Only in Germany? 30 minute line up to buy bread on a bright Sunday morning.

@grwUCL @ucl @School_Pharmacy @UoN_Pharmacy @AMDD_CDT Boom! Well done @grwUCL ! I trust this will fund all 60 of my PhD ideas.

Delighted that our new CDT in Accelerated Medicines Design & Development has been funded @ucl @School_Pharmacy 🥳, in partnership with @UoN_Pharmacy. Follow @AMDD_CDT for news and information as we stand the new centre up 🙂 #EPSRC_CDTs