Matthias P. Wymann

Need a chemical probe from @DepBiomedicine @UniBasel to explore PI3K signaling? See @ChemicalScience our newest article on a highly cell permeable covalent PI3Kalfa inhibitor: "Rapid, potent, and persistent covalent chemical probes to deconvolute PI3Kα signaling".

Covalent Proximity Scanning of a Distal Cysteine to Target PI3Kα - congrats Chiara Borsari, your paper made > 10000 article views! pubs.acs.org/doi/10.1021/ja…

Post-doc positions in Medicinal Chemistry, 100% for more info see and apply at career2.successfactors.eu/sfcareer/jobre… Project relevant, recent publication of our lab see doi.org/10.1021/jacs.1…

The role of PI3Kγ in the immune system: new insights and translational implications @NatRevImmunol by @lucasite_lab & @MatthiasWymann covers #Genetics and #drugdiscovery of #PI3K Now online at doi.org/10.1038/s41577…

Novel roadmap to target distal cysteines in kinases disclosed: covalent PI3Kalfa inhibitor in @BorsariChiara et al. @MatthiasWymann @DepBiomedicine@UniBasel_en @J_A_C_S #MedChem #CovalentProbes #StochasticApproach #rationaldrugdesign is online at pubs.acs.org/doi/10.1021/ja…