Menopause Research

This is a really important research paper so I wanted to share some of the key parts with you. There is evidence that body identical HRT can reduce dementia onset and also it is known that oestradiol can improve blood flow to the brain, reduce inflammation, improve mitochondrial function (which is what generates the energy to power cells), improve glucose metabolism in the brain, work as a neurotransmitter and improve dendrite density. Testosterone can also have beneficial effects on the brain including help to build the myelin sheath, which is what allows electrical impulses to transmit quickly and efficiently along the nerve cells. So the physiology of these hormones shows they improve brain function and therefore would suggest that they can reduce dementia risk.

@caitsith675 Thank you for bringing this to my attention.

It's not too late for BRCA & non BRCA women to sign up to this research project with #UCLH & @TheEveAppeal brcaprotect.org

VERY important petition for #Menopause support for women. Lets sign and bring it to parliaments attention!

CALLING ALL LADIES BETWEEN THE AGES OF 45-65 YEARS YOUNG. I am doing a research project on #Menopause and I would really appreciate if you could help me by completing my survey. It should only take 5-10mins. Thank you 💕 westminsterpsych.az1.qualtrics.com/jfe/form/SV_25…

10 essential menopause facts written by Villines, Z (2020). medicalnewstoday.com/articles/317765

Cavaco Silva, J (2018) writes about #Menopausal hot flashes and night sweats and treatments to cope with these symptoms. medicalnewstoday.com/articles/322351

@NikitaSilver6 There are so many pros to taking HRT. So sorry to hear about your experience!

@MenoResearch Personally, I believe every woman should take HRT if they can. It’s the only thing that can stop bone loss in its tracks. Around 50% of people, mainly women, only find out they have OP after they fracture. I only found out after the 2nd fracture. I was denied HRT.

If you have decided HRT is not for you, Harvard Health (2017) lists nonhormonal treatments to help with menopausal symptoms: health.harvard.edu/womens-health/…

@NikitaSilver6 However, we need to understand why women are disproportionately diagnosed with Alzheimer's compared to males. I found this article interesting because it speaks about sex differences in hormones and tau levels.

@NikitaSilver6 This article draws on a few research studies but yes, from my understanding the study that found the association between HRT and Alzheimer's used older types of HRT for their research.

Women account for more than two-thirds of all dementia cases. One risk factor may be early age at menopause, late start to hormone therapy Shukla, D. (2023)... medicalnewstoday.com/articles/alzhe…

As we know, oestrogen levels drop during #Menopause resulting in increased bone loss. Stevenson, J (2022) has written about prevention interventions for osteoporosis in women including #HRT #Estrogen calcium and vitamin D. journals.sagepub.com/doi/full/10.11…

49% of postmenopausal women did not feel informed at all about the menopause. Research by Aljumah et al., 2023. #Menopause This research really shows that Menopause is only now starting to get the attention it should. journals.sagepub.com/doi/full/10.11…

Personally, #HRT has helped physical aspects of very symptomatic #earlymenopause - but hasn't affected the psychological aspects. Even within physical symptom reduction, effects are not always consistent. So much more research needed to improve options and outcomes. #Menopause

Bailey, E. (2023) lists the pros and cons of Hormone Replacement Therapy: medicalnewstoday.com/articles/manag…

Recently I delivered a talk to 250 healthcare professionals who work in mental health teams to highlight the role of our hormones in relation to our mental health. As you’ll hear in this clip, we have oestrogen and testosterone receptors all over our bodies and in our brain as well. Each area of the brain plays a role in the way we think, the way we move and the way we act, and so when our hormone levels reduce, many women will experience psychological symptoms too. It’s really important that our hormones are considered when women are struggling with their mental health, so receiving this feedback from the consultant psychiatrist who organised the event is really good to see: “I must say I think we will all consider the menopause much more in our clinical practice after yesterday, I am keen to see if we can get some agreement or guidance around this and how we can potentially advise GP colleagues to consider HRT treatment if they have not done so already. I certainly will be suggesting it in my practice.” Thank you to Kehinde for organising the event with @NottsHealthcare @MedEdNottsHC . Hopefully we will see an improvement in mental health support for perimenopausal and menopausal women as a result.

Talaulikar, V. (2022) found 85% of women suffer from menopausal symptoms which can be physical as well as psychological. Further, the most effective treatment for relief of menopausal symptoms is still HRT. #Menopause sciencedirect.com/science/articl…

Mahboubeh et al., (2018) did a systematic review on strategies to improve menopausal quality of life. #Menopause #MenopauseJourney #WomensHealth ncbi.nlm.nih.gov/pmc/articles/P…