Marcos Francisco Perez

@TMB_Barcelona el web del concurs de Relats Curts no funciona. Ens torna al principi quan intentem autenticar en JoTMB. No puc pujar el relat de la meva filla despres de tant esforc :(

@TMB_Barcelona La web no funciona - no podem accedir-hi per pujar les nostres histories... quan ho intentem, hem d'autenticar de nou i ens torna al principi

❗Últim dia ❗🚇🚍 Si et mous amb TMB, tens una història. A què esperes per imaginar i escriure la teva? Participa al Concurs de Relats Curts i fes-la viatjar més lluny que mai! #RelatsTMB2026 🔗 ow.ly/Nxf950YhwmO

Bit delayed, but proud to share the first publication from my lab - CelEsT, a gene regulatory network for estimating transcription factor activities in C. elegans - now out in Genetics. Open-access link below: academic.oup.com/genetics/advan…

Pleased that the first preprint from my lab is on bioRxiv today! CelEsT - a unified and benchmarked gene regulatory network for estimating transcription factor activity in my beloved C. elegans biorxiv.org/content/10.110…

📢 El @IRSJD_info y @IRBBarcelona fortalecen su colaboración en la investigación del cáncer pediátrico. 🤝El acuerdo incluye la apertura de un laboratorio, liderado por la Dra. @AAvgustinova Lee la noticia completa ⬇️ sjdhospitalbarcelona.org/es/noticies/ir…

📢 It´s finally here! I´m thrilled to announce the opening of the Pediatric Cancer Epigenetics lab at #IRBBarcelona and @IRSJD_info! 🎉 I'm overflowing with excitement to lead groundbreaking research aimed at helping pediatric cancer patients. #IRBScience #PCCB

Are you interested in where childhood cancer comes from, and how we can use this knowledge to design targeted therapies? 👩‍🔬Join us in sunny Barcelona - hiring at all levels! PhD call: bit.ly/3SLlIdi Postdoc: bit.ly/3SCECTw Lab Manager: bit.ly/46pMACQ

Check out our primer on a great paper by @MfPez & @PSarkies uncovering histones as methylation sinks in human cells. Histone methylation reflects cellular methylation potential independently of gene reg. Time to consider chromatin a metabolic organelle 1/3 journals.plos.org/plosbiology/ar…

A role for #HistoneMethylation in metabolic regulation? #Histone methyltransferases are co-regulated by #TumorSuppressor Rb; altered expression controlled by Rb leads to reorganization of S-adenosyl methionine metabolism @MfPez @psarkies #PLOSBiology plos.io/3MhUfM4

@VashKurdistani @PSarkies Thanks indeed for the clear explanation and the kind words!

Super excited and honoured to receive the #ERCStG to study what determines oncogenic competence during development! Thank you @ERC_Research, my brave lab members, all of my mentors and everyone who supported me along the way! Stay tuned for new positions: We will be hiring soon!

Convergent evolution x.com/slender_sherbe…

@KlosinAdam @GenomeBiology @PSarkies Good question - I speculate that since OXPHOS expression level is tissue regulated, that's probably good enough for most unstressed tissues. Most mito-nuclear signalling has been studied under physiological stress. But just speculation (double rainbow all the way!)

@MfPez @GenomeBiology @PSarkies Should I take from this that OXPHOS is a honey badger that don't care about subunit stoichiometry? Or is it regulated posttranscriptionally?

My first tweetorial on my first computational paper in @GenomeBiology with @PSarkies! In which my naivete was an asset. If you like mitochondria or ever do correlations of RNA-seq gene expression, have a look (1/12)

Check out the paper (open-access) at Genome Biology - here’s the link: rdcu.be/cCwCt (12/12)

And once we got past that technical issue, we found a surprising lack of general mitochondrial-nuclear coordination, except in cancer (11/12)