Eugene B Chang, MD

@Neelp12 Postbiotics are what microbes make that might have beneficial effects, e.g. short chain fatty acids, tryptophan metabolites, certain vitamins and essential amino acids. This way, you can deliver effective concentrations without worrying about microbe engraftment.

@MicrobiomeDoc Thank you what do you suggest or mean by postbiotics.

Check out our most recent paper that shows that correction of early life gut dysbiosis with a single keystone species can restore immune tolerance and significantly reduce risk for colitis later in life in genetically-prone mice. gastrojournal.org/article/S0016-…

@Suzanne_Devkota Glad you are better.

@MicrobiomeDoc Yes I hear the heel is so painful. Mine was in the intra-articular space in my shoulder. Yesterday was awful, but my end of day dissipated and today pain is gone 👍🏼

I’m not one to crowd-source info on my health, but here I am. Looking for advice for those of you who’ve had cortisone injections in a joint. Had one in my shoulder this AM, pretty awful needle-like pain at the site and all down my arm now. Normal? And how long does this last?

@Neelp12 Sorry. Too many issues with probiotics. Strain engraftment may be important and likely very individual specific, i.e. a single strain isn't likely to work for all. Also, most probiotics are unlikely to survive or work in inflammation. Postbiotics might be better options, IMHO.

@MicrobiomeDoc Would you suggest any particular strains or probiotics for crohns patients.

@Neelp12 The strain was a type of Bacteroides species that is likely a foundational species specific to the mouse gut microbiome. We suspect that there are many human-specific strains that have the same fundamental properties for maturing the gut microbiome and immune system.

@MicrobiomeDoc What strain is best as unable to open article.

@Suzanne_Devkota Move back to Chicago

Weird earthquake last night. More of a sharp jolt than the rolling kind. Made my doors slam and sent my dog running to the door thinking someone was breaking in. #SoCalnormal

Excited for #StarTrekPicard

#DDW2020 members-only registration is now open. If you're a member of @AASLDtweets @AmerGastroAssn @ASGEendoscopy or @SSATNews you can take advantage of this special opportunity to register early & secure housing: ow.ly/v6EK50xW7z8

Dr. Eugene Chang at @UChicagoMed is also Chief Medical Officer at AVNovum, a #microbiome startup he co-founded and backed by @polskycenter. Come celebrate Dr. Chang and the two other honorees at the Halo Awards on Thurs, Oct 25 @MATTERhealth #thehalos buff.ly/2LEdDVF