MOBILion Systems

Miriam Fico is our March MOBILion Champion 🎉 Always ready to step in, solve problems, and support the team, Miriam connects R&D, Product, and Applications while continuously improving how we work. Congrats, Miriam! 👏 #Trailblazers2026

Abandoning the Quadrupole with PAMAF™ That’s not the full story. SLIM + PAMAF shifts LC-MS performance from duty cycle to ion utilization, enabling 100× signal gains and >1000 Hz speeds on a QTOF. Read more: genomeweb.com/proteomics-pro… #Proteomics #PAMAF

Sometimes what looks like one peak… isn’t. Co-eluting compounds make it hard to tell what you’re seeing, impacting confidence. At Los Alamos, Austin Anderson’s team is evaluating MOBIE® to add a second separation dimension and resolve LC overlaps. #Trailblazers2026

Separating closely related lipid molecules remains a major analytical challenge. At the Gordon Research Seminar & Conference on Lipidomics, Amie Solosky will present work using high-resolution ion mobility to distinguish oxylipin isomers. GRS: Mar 15, 9:20 AM PST | GRC: Mar 18

What happens when you add a gas-phase separation between LC and MS? In Episode 50 of Concentrating on Chromatography, MOBILion CTO Daniel DeBord discusses HRIM, SLIM, and how ion mobility is expanding analytical workflows. Watch: youtube.com/watch?v=fDJX6v…

Clinical research demands faster results without sacrificing data quality. Tim Garrett’s lab uses ion mobility to add an extra separation dimension, enabling faster analysis while maintaining the sensitivity needed for complex biological samples. #Trailblazers2026 #IonMobility

Happy International Women's Day! At MOBILion Systems, we’re grateful for the incredible women across our organization who bring leadership, talent, and dedication to everything they do. They truly bring the heart to our company. #InternationalWomensDay

The MOBILion team stepped out of the lab and into the kitchen, volunteering at Ronald McDonald House to prepare meals for families whose children are receiving medical care. Grateful to support an organization that provides comfort and community when families need it most.

Two-dimensional separations solve problems 1D methods can’t. A new study from Oliver Schmitz’s lab adds multidimensionality at the ion source with rapidly switchable ESI + plasma ionization, paired with HRIM from MOBILion on an Agilent QTOF. Read: pubs.acs.org/doi/pdf/10.102…

Behind every high-resolution measurement is the need to turn complex data into meaningful insight. As an Informatics Scientist at MOBILion, Lauren Royer Dissinger ensures ion mobility data is reproducible, high-quality, and actionable for researchers. #Trailblazers2026

Heading to #Pittcon2026? Join MOBILion’s Lauren Royer for an oral presentation on how PAMAF™ + HRIM enables precursor–fragment alignment without quadrupole isolation, improving fragment coverage and delivering >3× protein IDs. 📍Room 304C | Mar 11 | 9:40 AM

Lysine succinylation regulates metabolism but remains difficult to quantify proteome-wide. Using PAMAF™ on a SLIM-enabled HRMS prototype, Schilling et al. resolved isomeric PTMs and quantified ~1,000 succinylated peptides in tissue samples. sciencedirect.com/science/articl…

Some of the hardest challenges in proteomics and metabolomics appear after measurement. As Gary Patti noted, faster workflows often trade certainty for speed. Adding another separation dimension is helping labs gain confidence without added complexity. #Trailblazers2026

Meet our February MOBILion Champion: Michael Slemko. Mike brings systems-level thinking, steady leadership, and cross-functional collaboration to every challenge, creating clarity, driving alignment, and raising the bar for those around him. Congrats, Mike! #Trailblazers2026

Quadrupole isolation wastes ions and creates chimeric MS/MS. Our new preprint with Biognosys & Benjamin Orsburn introduces PAMAF™: size-based isolation in mobility space with near-100% ion use and >500 Hz MS2.8,000+ proteins in DIA-PAMAF. biorxiv.org/content/10.648…

Samples often look simple, until you have the separation power to reveal what’s hiding. By pairing LC, LCxLC & GC with high-resolution ion mobility, Oliver uncovered signals earlier workflows left blended together. Cleaner MS/MS. Faster IDs. Greater confidence. #Trailblazers2026

“What would you tell a girl who thinks science isn’t for her?” For International Women & Girls in Science Day, we asked the women of MOBILion to share their thoughts. One message stood out: there’s more than one way to belong in science. What would you say? 👇 #WomenInSTEM

“This complexity calls for an additional dimension of separation beyond chromatography.” Genentech demonstrates HRIM resolving PS diastereomers across therapeutic oligos, turning a trial-and-error challenge into a predictable analytical strategy. pubs.acs.org/doi/10.1021/ac…

Using ion mobility has often meant trading breadth for focus. For Christopher Chouinard, high-resolution ion mobility changed that, enabling wide, untargeted separations that deliver clearer identification in complex, real-world samples. #Trailblazers2026

Our CTO Daniel DeBord is heading to US HUPO 2026 with 3 presentations you won’t want to miss: ⚡Lightning Talk + Poster: Waste Not, Want Not (single-cell proteomics) 🧬Poster: From Blind Spots to Breakthroughs (PTM analysis) Connect with Daniel or Mick Greer while you’re there.