Helen

Postoperative ischaemic stroke was more common in patients with long-term preoperative #betablocker prescription after #noncardiacsurgery bjanaesthesia.org/article/S0007-…

Regular exercise is linked to slower biological aging - but only in people sleeping 7+ hours. People who slept under 6 hours and exercised actually aged faster.

Movement is medicine. Large systematic review of over 1,000 trials and 120,000 participants finds that exercise has a significant effect on symptoms of depression, anxiety, and psychological distress. We need to do a better job of integrating mental and physical health.

Small amounts of exercise are associated with large reductions in cancer risk. 4.5 minutes per day is associated with 31% reduction in cancer incidence.

This systematic review and meta-analysis finds that exercise is likely to enhance endothelial function in patients with cardiovascular disease and that high-intensity interval aerobic exercise demonstrates superior efficacy over moderate continuous exercise.

🏃‍♂️🫀 Exercise Prescriptions Should Be Risk-Stratified — Not Generic Current guidelines recommend ≥150 min/week of moderate-to-vigorous physical activity (MVPA) for everyone. But is that optimal for a 45-year-old low-risk individual and a 70-year-old very high-risk patient? This large UK Biobank cohort (72,884 participants, median 13.2-year follow-up) provides a more nuanced answer  . 🔬 What’s innovative? • Objective 7-day wrist accelerometer data • ESC-aligned SCORE2 risk stratification • Isotemporal substitution modeling (reallocating sedentary time) • Identification of optimal vigorous activity thresholds by risk group 📊 Key findings Each +150 min/week MVPA → • 20% lower CVD risk in very high-risk individuals • 16% reduction in high- and low-to-moderate-risk groups Higher-risk individuals benefit the most from increasing activity. BUT intensity matters. When replacing 300 min/week sedentary time: 🔹 Low-to-moderate risk → Any mix of moderate (MPA) and vigorous (VPA) works. More VPA = more benefit. 🔹 High risk → VPA should be ≤60 min/week (~20% of MVPA). 🔹 Very high risk → Optimal VPA ≈ 42 min/week (~14% of MVPA). Beyond that, benefits decline. In high-risk groups, excessive VPA may attenuate benefit—likely due to hemodynamic stress, endothelial dysfunction, and oxidative burden. 🎯 Take-Home Messages 1️⃣ Physical activity remains powerfully protective across all risk strata. 2️⃣ Higher-risk patients gain the largest relative benefit. 3️⃣ Vigorous exercise has a ceiling effect in high-risk individuals. 4️⃣ Exercise prescriptions should integrate formal risk stratification (e.g., SCORE2). Precision prevention now extends to lifestyle medicine. One size does not fit all.

A #registrystudy showed that less than half of planned post-elective surgery #ICUadmissions were #resourceintensive bjanaesthesia.org/article/S0007-…

💊 Read a summary of "A preventive care strategy to reduce moderate or severe acute kidney injury after major surgery (BigpAK-2): A multinational, randomised clinical trial," in the March 2026 Science, Medicine, and the Anesthesiologist: ow.ly/mHnM50YljSQ

The latest update is live! Systematic review & meta-analysis looking at association between GLP-1 RAs, retained gastric content, and aspiration risk. #Anaesthesia #Anesthesiology #Surgery doi.org/10.17608/k6.au…

They counted every drug & item used in 16 day-case laparoscopic cholecystectomies. They documented actions in the anaesthetic room, OT, recovery & gas flows. They calculated life cycle emission analysis across 169 drugs & equipment. What did they find? #anaesthesia #climate #MedTwitter doi.org/10.1111/anae.7…

Systematic review and meta-analysis: Prophylactic TXA use was associated with lower intraoperative blood loss, transfusion requirements, and major bleeding without an observed increase in thromboembolic or mortality risk. ja.ma/4c8OJZU

Effect of exercise on depression and anxiety symptoms 🏃‍♂️ 🧠 NEW systematic umbrella review with meta-meta-analysis 📄 see the key findings👇 #FREE ➡️ bit.ly/4aypw91

Perioperative #anaemia is a known risk factor for adverse outcomes in #cardiac surgery. Evidence focuses on pre-op Hb, but post-op Hb drop is also associated with increased risk of 30-day mortality and major morbidity bjaopen.org/article/S2772-…

Peri-operative management of diabetes mellitus: a multidisciplinary consensus statement from the Association of Anaesthetists and the Joint British Diabetes Societies for Inpatient Care group @nicholasalevy @elboghdadly @DL08OMD @djramsaystubbs @padoscan @gasorrun @ketandhatariya #anaesthesia #MedTwitter #endocrine #diabetes doi.org/10.1111/anae.7…

Recommendations for solid food and liquids in the peri-operative period. #anaesthesia #MedTwitter doi.org/10.1111/anae.7…

Public health policies and interventions to address health inequities in high-income countries: an umbrella review link.springer.com/article/10.118… via @JatinderHayre_ et al

Cardiopulmonary fitness in patients undergoing major hepato-pancreatobiliary surgery who are non-anaemic and iron replete vs. non-anaemic and iron deficient: an observational study #anaesthesia #MedTwitter doi.org/10.1111/anae.7…

1/2: On #WorldCancerDay, we’re highlighting the new #NationalCancerPlan from @DHSCgovuk and the role that clinical audit and healthcare data play in improving cancer survival.

Is STOP-BANG too subjective? Is there an alternative? The B-APNEIC score showed strong predictive accuracy for severe obstructive sleep apnoea and could serve as a simple, objective alternative to STOP-BANG. #AnSky #MedTwitter doi.org/10.1111/anae.7…