

NR IMPACT
119 posts

@NR_IMPACT
A collaborative group for early- and mid-career faculty who study nuclear receptors. Advancing science and career development.















Please RT: ER/E2/breast cancer. We are seeking #crowdsourced datasets and opinions. We curated 136 published datasets, processed with one pipeline and made a browser to visualize E2-induced expression and ER binding. Feel free to try it out estrogene.org 🧵


Molecular basis of ligand-dependent Nurr1-RXRα activation biorxiv.org/content/10.110… #NuclearReceptors #NMR #TR-FRET

Fantastic job by @ZheqiL and others in the lab. Thanks @mjsikora @JCarrollLab for help. Maybe @NR_IMPACT can take this on for other receptors, other tumor types? In the meantime pls provide #feedback 🙏 #bcsm





#dark_kinases #randomactofkinases SGC-CAMKK2-1: A chemical probe for CAMKK2 biorxiv.org/content/10.110… #sgcunc; @thesgconline; @dhdrewry




How do bile acids impact the microbiome and disease? Penn State researchers @cdokafor, @PSUmetabolomics, @JordanBisanz, @JonathanStineMD and @Steph_L_Collins review what is known in this interesting and expanding field of research: