
New preprint! These elongating embryo-like structures formed entirely from sheep stem cells in vitro. They develop neural tubes, somites, neurons, and kidney progenitors — modeling post-gastrulation trunk development. 🧵👇 1/8
Naama Fa
10 posts

@NaamaFa
PhD student, research in-vitro models of embryo development Iftach Nachman's lab

New preprint! These elongating embryo-like structures formed entirely from sheep stem cells in vitro. They develop neural tubes, somites, neurons, and kidney progenitors — modeling post-gastrulation trunk development. 🧵👇 1/8

Online now: Coordination between endoderm progression and mouse gastruloid elongation controls endodermal morphotype choice dlvr.it/T7qQrb


Why are in-vitro embryo-like models so variable, while the embryo develops so robustly? We try to tackle this in a new preprint, using the gastruloid model and morphogenetic progression of definitive endoderm (DE). biorxiv.org/content/10.110…




