Nautilus Biotechnology

Nautilus’ Iterative Mapping Early Access Program gives you the unique opportunity to employ our novel single-molecule proteomic analysis method and platform for your research. Join Now: bit.ly/49dpO5M Our initial fee-for-service offering through the program enables you to be among the first to deeply explore the human tau protein by quantifying up to 768 full-length tau proteoforms in your samples of interest. Studying these previously inaccessible forms of the tau protein may be critical to understanding neurodegenerative diseases as well as developing novel biomarkers and precision medicines. Even if your project doesn’t involve tau, we welcome prompt completion of the form on the page linked here as spots in the program will be limited. We look forward to working with you!

Professor Birgit Schilling from the Buck Institute for Research on Aging recently joined Sheri Wilcox, Nautilus VP of Scientific Engagement at our US HUPO 2026 lunch seminar. During the seminar, Birgit shared fascinating new single-molecule proteomic data that’s already beginning to deliver insights into Alzheimer Disease biology. In this blog post, we briefly outline the topics covered in the seminar. nautilus.bio/blog/nautilus-… You can also access a recording of the full seminar here: nautilus-21430832.hs-sites-na2.com/us-hupo-2026-l…

If you're interested in becoming an Iterative Mapping Early Access Program customer and being one of the first to bring single-molecule proteomics into your workflows, fill out the form here: nautilus.bio/nautilusEAP/

We're proud to announce Baylor College of Medicine as the first customer of our Iterative Mapping Early Access Program! In a study led by Baylor Professors Bing Zhang, Ph.D. and Yongchao Dou, Ph.D, Baylor researchers will leverage the Nautilus Voyager™ Platform to address a central challenge in cancer research – identifying aberrant protein isoforms that contribute to tumor growth, metastasis, immune evasion, and therapeutic resistance. The study aims to develop a broadly accessible computational toolkit with improved detection of protein isoforms in conventional shotgun proteomics datasets. By pairing these computational approaches with full-length, isoform-resolved proteomic measurements generated on the Nautilus Voyager Platform, the project enables direct comparison of transcriptional and proteomic changes at unprecedented resolution. Learn more in our latest press release: globenewswire.com/news-release/2…

For a great summary of our incredible progress over the last 9 years and to discover how we're entering the market with our Iterative Mapping Early Access Program, check out this episode of The Biotech Startups Podcast featuring Nautilus Co-Founder and CEO Sujal Patel. Some highlights: 🔵 4 key technological advances at Nautilus 🔵 How Sujal applied his previous startup experience to drive progress at Nautilus 🔵 What's in store for Nautilus over the next few years Find the podcast here: Apple Podcasts: podcasts.apple.com/us/podcast/you… Spotify: open.spotify.com/episode/0WGC5Q… YouTube: youtube.com/watch?v=xk-cQW… Many thanks to Jon Chee and Excedr for this fantastic interview series!

We're excited to share that Nautilus Senior Director of Scientific Affairs and Alliance Management, Andreas Huhmer, Ph.D., will be at #ADPD2026! He'll be at his poster (#608) on March 17th & 18th from 10:30am - 1:30pm. Check it out to discover how work powered by Iterative Mapping on the Nautilus Voyager Platform is already beginning to show that tau proteoform profiles have the potential to differentiate samples from cognitively normal and cognitively impaired patients. We look forward to working with more members of this community to discover how tau proteoforms impact disease biology and hope work like this will guide the development of next-generation biomarkers and drug targets. If you'd like to use the Nautilus Voyager Platform to explore tau biology with single-molecule clarity, join our Iterative Mapping Early Access Program: nautilus.bio/nautilusEAP/

The Nautilus Voyager™ Platform is an all-in-one system for comprehensive single-molecule proteomic analysis. We recently unveiled the Voyager Platform at an after-hours event at US HUPO 2026 titled, “A magical evening with Nautilus at US HUPO 2026," and its debut was featured on the Nasdaq building in Times Square! We discuss some of what made the event “magical” in our latest blog post: nautilus.bio/blog/introduci…

US HUPO 2026 represented a critical milestone for Nautilus. At the conference we: 🔵 Revealed new Iterative Mapping data generated by the Schilling and Ellerby Labs at the Buck Institute for Research on Aging providing strong evidence that proteoform analyses can reveal biological differences hidden at other levels of protein biology. 🔵 Invited attendees to be among the first researchers to use Iterative Mapping in their own work through the Iterative Mapping Early Access Program. 🔵 Unveiled the Nautilus Voyager Platform for the first time! Explore the data and meet the Voyager Platform yourself in this blog post: nautilus.bio/blog/revealing…

We're proud to announce that Amber Faust has joined the Nautilus team as Vice President of Sales! Amber comes to Nautilus with extensive experience leading and driving sales in the proteomics space, and we are excited to work with her to accelerate commercial progress of the Voyager Platform. globenewswire.com/news-release/2…

Company’s new benchtop system promises a clearer view of proteins following validation at a leading aging research institute. longevity.technology/news/nautilus-… #longevity #proteomics #biotechinnovation #agingresearch #drugdiscovery #precisionmedicine #lifescience

Fresh off our time at US HUPO 2026, we’re excited to share the latest episode of Translating Proteomics featuring US HUPO President-Elect, Professor Olga Vitek Ph.D. from Northeastern University! In this episode, Olga chats with Parag about the importance of statistics in experimental design, how statistics and AI can help researchers understand biology, and the data gaps that prevent AI and statistics from achieving their maximum potential in biology. Check it out here: nautilus.bio/blog/ai-and-st…

Today at US HUPO 2026 - Join Sheri Wilcox and Birgit Schilling for our lunch seminar titled, "Revealing the proteomic landscape with Iterative Mapping." Time: 12:30pm - 1:30pm CST Place: Grand AB at the Hyatt Regency St. Louis Sheri will share how Iterative Mapping is designed to achieve both coverage and detail in proteomic analyses and Professor Schilling will discuss how her lab at the Buck Institute for Research on Aging is already using the Nautilus Voyager Platform to reveal novel insights into tau proteoform biology. Find all of our HUPO 2026 events here: lnkd.in/gVNZDPAe

We’re incredibly proud to share that we unveiled the Nautilus Voyager Platform at US HUPO 2026! Learn more about the Voyager Platform in our press release: globenewswire.com/news-release/2… And visit our website to discover how all the components of the Voyager Platform come together to enable Iterative Mapping: nautilus.bio/voyager-platfo…

If you're at US HUPO 2026, be sure to drop by Booth 25 to chat with members of the Nautilus team, explore how the Nautilus Platform is redefining proteomic discovery, and learn how you can be one of the first to use the Nautilus Platform in your research through our Iterative Mapping Early Access Program. Find all of our US HUPO 2026 events here: nautilus-21430832.hs-sites-na2.com/us-hupo-2026-e… #USHUPO2026

Later today at US HUPO 2026, find Andreas Huhmer at his poster titled, "Iterative Mapping of Tau Proteoforms Uncovers Regional Heterogeneity in Alzheimer’s Disease" You can find all of our US HUPO 2026 events here: nautilus-21430832.hs-sites-na2.com/us-hupo-2026-e…

We're excited to be at US HUPO 2026! You'll find members of the Nautilus team at Booth 25 throughout the conference, and tomorrow Sheri Wilcox will deliver an oral presentation covering how we're "Advancing Proteomics with Iterative Mapping" at 11:00am in Park View. Sheri will also be giving a lightning talk later in the day. Find all of our US HUPO 2026 events here: nautilus-21430832.hs-sites-na2.com/us-hupo-2026-e…

US HUPO 2026 is just around the corner! Join us at the events listed below to discover how Iterative Mapping is revealing hidden swaths of the proteomic landscape and enabling researchers to find what matters. At the conference, we’ll also share how you can join the Iterative Mapping Early Access Program and be one of the first to use Iterative Mapping in your research. Explore our US HUPO 2026 events and set up one-on-one meetings with the Nautilus team here: nautilus-21430832.hs-sites-na2.com/us-hupo-2026-e… #USHUPO2026 #USHUPO #Proteomics

Checkout a new podcast I was on discussing multi-omics in space and some of my other work with AI....

New $1.6m collaboration aims to detect Parkinson’s disease earlier by tracking proteins one molecule at a time. longevity.technology/news/nautilus-… #longevity #Proteomics #ParkinsonsResearch #EarlyDetection #PrecisionMedicine #SingleMolecule #Neurodegeneration #BiotechCollaboration

Unlock the future of proteomics! 🚀 Explore the innovative Nautilus Proteome Analysis Platform in our new free eBook from @NautilusBio. Download now: hubs.li/Q03-FFgx0 #Proteomics #Biotechnology #Research #Innovation #eBook

What happens to the human body when we leave Earth—and how can multiomics help us understand (and mitigate) those effects? In this episode of #TranslatingProteomics, Parag Mallick sits down with Profesor Afshin Beheshti from the University of Pittsburgh to explore: 🚀 How spaceflight alters biology from mitochondria to immunity 💪 Why proteomics is essential for understanding frailty, aging, and recovery in astronauts 🌍 How space research accelerates breakthroughs here on Earth Listen now: Translating Proteomics — OMICS IN SPACE nautilus.bio/blog/omics-in-…