Ed Needham

How to Read an #EEG strikes back -- Now covering "#Epileptiform Abnormalities"! ⚡️🧠 @KNascimenski @SBeniczky @DrHirschEEG tinyurl.com/EEGx2

A small 🧵 encouraging people to publish protocols. Our #AutoSpectral release has made me reflect on how much the community tends to appreciate protocol papers. People rarely present protocols as their main work, but they are often the most impactful biorxiv.org/content/10.110…

Pre-print alert! And this one really is a must read for anyone that does spectral flow cytometry. It is a complete, fully-automated spectral unmixing pipeline that reduces error up to 9000-fold. Want to get a tough sample, like lung, looking like this? biorxiv.org/content/10.110…

I attended a Ska/2 Tone revival concert yesterday. This morning, and thinking about it, I find it depressing how the movement's essential message is still relevant and still needed. Great band, though.

Just had my first piece for @bmj_latest Opinion published. Thanks to @dr_mattmorgan for the encouragement. Hopefully it’ll resonate with EM colleagues. bmj.com/content/390/bm…

This study highlights the complexity and diversity of the AChR autoantibody repertoire, suggesting its potential impact on responses to treatments among patients with myasthenia gravis: hubs.la/Q03KmrXw0 #NeuroX #NeuroTwitter

For our #flowcytometry peeps, would you like to have a single fix/perm protocol that is optimised for everything? One that preserves fluorophores while allowing simultaneous TF and cytokine staining? How about 100-fold cheaper? You got it: …rentprotocols.onlinelibrary.wiley.com/doi/10.1002/cp…

Inspiring first day at TBI-REPORTER General Assembly. A photo of all participants and delegates who’ve contributed to the discussions today. #UKABIF #TBI #REDCap #cognitron #aquiredbraininjury

Many congratulations to Michael Baker on putting together this detailed analysis of metabolic abnormalities after moderate-severe Traumatic Brain Injury incorporating ICP, MD and autoregulatory indices @_SaraVenturini_ @pja_hutch eur03.safelinks.protection.outlook.com/?url=https%3A%…

We are pleased to announce the launch of a new taught MPhil programme in Brain Health and Disease: Clinical Neurosciences at the University of Cambridge. We are currently seeking a Course Coordinator to support this new programme. Please see: cam.ac.uk/jobs/course-co…

Othman et al. studied the impact of apomorphine and methylphenidate on consciousness biomarkers and clinical arousal in ICU patients with brain injury, in a randomized placebo-controlled trial. tinyurl.com/5w3j58pt

Passionate about neuroimaging and data science? Join the @TBI_REPORTER as a Postdoctoral Research Associate in Image Analysis. You'll work with scientists, clinicians & industry partners globally to develop and execute imaging analysis pipelines. APPLY: buff.ly/wJcHhLa

Beware commercial tissue based assays (TBAs) to detect cell surface autoantibodies in neurology. TBAs are often used as screening tests and are reader dependent. Bottom line: please think clinically when diagnosing autoimmune neurological syndromes pubmed.ncbi.nlm.nih.gov/40393020/

and how dysfunctional meningeal lymphatics regulate synaptic physiology in a microglia-dependent manner cell.com/cell/fulltext/…

Implementation of 2HELPS2B Seizure Risk Score: A Cost-Effective Approach to Seizure Detection in the Intensive Care Units hubs.la/Q03kXHmV0

Redefining CNS immune privilege bit.ly/432fwRC

#CASPR2-#antibody diseases are provide clues to mechanisms of autoantigen-specific tolerance Here - in @ScienceAdvances - we show how central and peripheral B cell tolerance licences pathogenic CASPR2 antibody generation. science.org/doi/10.1126/sc… More below 👇🏿

Microglia dysfunction, neurovascular inflammation and focal neuropathologies are linked to IL-1- and IL-6-related systemic inflammation in COVID-19 @NatureNeuro nature.com/articles/s4159…

A huge privilege to participate in the @ARUKscientist debate, discussing hope for future treatments for devastating dementias but also practical barriers to delivering current therapies both in NHS @CPFT_NHS and privately @spirehealthcare that need to be overcome for a true cure

About half of patients with NPH and parkinsonism have an abnormal DaT SPECT, but they do not have nigrosomal loss like in PD! Is their parkinsonism from mechanical disruption rather than neurodegeneration? Check out this cool study! tinyurl.com/4k7bkd5b