NeurAxis, Inc.

We’re excited to see the continued expansion of IB-Stim® training across leading pediatric GI programs. Congratulations to Dr. Tracie Wong (right) and Dr. Shamila Zawahir (left) at Joseph M. Sanzari Children's Hospital of @hackensackmeridianhealth for recently completing their training for IB-Stim and expanding access to a drug-free treatment option for children and adolescents with abdominal pain associated with IBS and functional dyspepsia. IB-Stim, a percutaneous electrical nerve field stimulation device (PENFS), is indicated for patients 8 and older who suffer from functional abdominal pain due to IBS, functional dyspepsia (FD), and FD-related nausea symptoms. For important IB-Stim information, including indications, precautions, IFU, and contraindications, visit: ibstim.com/important-info… #PediatricGI #IBStim #FunctionalAbdominalPain #FunctionalDyspepsia #IBS #Gastroenterology #PediatricHealthcare #Neuromodulation

IBS awareness includes recognizing that functional abdominal pain associated with IBS may involve altered signaling along the brain-gut axis rather than structural disease. This distinction can influence how pediatric patients are evaluated and how care plans are developed, particularly for those who have not responded to initial therapies. During IBS Awareness Month, continued focus on mechanism-based understanding may support more informed clinical decision-making. IB-Stim® is FDA-cleared for patients ages 8 years and older with functional abdominal pain associated with IBS and functional dyspepsia. In patients with functional dyspepsia, IB-Stim has also been shown to address associated nausea symptoms. Explore the mechanism: ibstim.com/how-ib-stim-wo… For important IB-Stim information, including indications, precautions, IFU, and contraindications, visit: ibstim.com/important-info… #IBSAwarenessMonth #PediatricGastroenterology #FunctionalAbdominalPain #IBS #Neuromodulation #BrainGutAxis #GIHealth #IBSAwarenessMonth #MoreThanAStomachache

April is IBS Awareness Month, a time to highlight the clinical complexity of disorders of gut-brain interaction and their impact on pediatric patients. Functional abdominal pain associated with IBS remains a common reason for pediatric GI visits, with management approaches varying based on underlying mechanisms and patient presentation. For children and adolescents, evaluating central pain processing may be an important component of care. IB-Stim® is FDA-cleared for patients 8 years and older with functional abdominal pain associated with IBS and functional dyspepsia. This non-drug, neuromodulation device can be incorporated into care plans for appropriate patients. Learn more: ibstim.com/how-ib-stim-wo… For important IB-Stim information, including indications, precautions, IFU, and contraindications, visit: ibstim.com/important-info… #IBSAwarenessMonth #PediatricGI #FunctionalAbdominalPain #IBS #BrainGutAxis #Gastroenterology #DGBI #IBSAwarenessMonth #MoreThanAStomachache

IB-Stim is a percutaneous electrical nerve field stimulator system intended for patients ages 8 years and older with functional abdominal pain associated with IBS and FD. It is used 120 hours per week for four consecutive weeks as an aid in the reduction of pain when combined with other therapies for IBS and FD. In patients with FD, IB-Stim has also been shown to reduce nausea symptoms. See how IB-Stim integrates into pediatric GI care: ibstim.com/how-ib-stim-wo… For important IB-Stim information, including indications, precautions, IFU, and contraindications, visit: ibstim.com/important-info… #IBStim #PediatricGI #FunctionalAbdominalPain #StandardOfCare #Neuromodulation #IBS #FunctionalDyspepsia #Gastroenterology #NonDrugOption

Functional abdominal pain associated with IBS and FD involves altered signaling along the brain gut axis. IB-Stim delivers percutaneous electrical nerve field stimulation to cranial nerve branches in the ear to modulate central pain pathways. Preclinical electrophysiology research has demonstrated modulation of the amygdala.* Clinical studies in adolescents showed improvements in pain measures and vagal efficiency.** *Babygirija R et al. Neuroscience. 2017;356:11 to 21 **Kovacic K et al. Lancet Gastroenterol Hepatol. 2017;2:727 to 737 IB-Stim is FDA-cleared for patients ages 8 years and older with functional abdominal pain associated with IBS and FD. In patients with FD, IB-Stim has also been shown to reduce nausea symptoms. Learn how IB-Stim works: ibstim.com/how-ib-stim-wo… For important IB-Stim information, including indications, precautions, IFU, and contraindications, visit: ibstim.com/important-info… #IBStim #BrainGutAxis #Neuromodulation #PediatricGastroenterology #GIHealth

In a randomized, double-blind, sham-controlled trial, 59% of adolescents treated with IB-Stim achieved at least a 30% reduction in worst abdominal pain compared to 26% in the sham group.* Statistically significant between-group differences were observed in worst pain and PFSD composite scores, with the largest separation seen at week 3. *Kovacic K et al. Lancet Gastroenterol Hepatol. 2017;2:727–737. IB-Stim is FDA-cleared for patients ages 8 years and older with functional abdominal pain associated with IBS and functional dyspepsia. Review the clinical data to determine whether IB-Stim may be appropriate for your patients. Learn how IB-Stim works: ibstim.com/how-ib-stim-wo… For important IB-Stim information, including indications, precautions, IFU, and contraindications, visit: ibstim.com/important-info… #IBStim #PediatricGI #FunctionalAbdominalPain #IBS #FunctionalDyspepsia #Neuromodulation #BrainGutAxis #EvidenceBasedMedicine #Gastroenterology

🎉 A major milestone for the Guidance and Patient Support (GPS) Program! NeurAxis is proud to announce that the GPS Program has now supported more than 3,500 patients since its launch, helping families navigate the path to care for pediatric and adolescent functional abdominal pain. In 2025 alone, the program assisted over 1,000 patients, working alongside pediatric gastroenterology teams to help address common access barriers such as insurance navigation, prior authorization support, and financial assistance resources. The continued growth of GPS reflects the dedication of providers and care teams committed to improving patients ages 8 and older who suffer from functional abdominal pain due to IBS, functional dyspepsia (FD), and FD-related nausea symptoms. Thank you to the many clinical partners who continue to collaborate with us to expand access and support families along their care journey! Learn more about the Guidance and Patient Support Program: ibstim.com/guidance-patie… For important IB-Stim information, including indications, precautions, IFU, and contraindications, visit: ibstim.com/important-info… #IBStim #PediatricGI #FunctionalAbdominalPain #FunctionalDyspepsia #IBS #PatientAccess #PediatricHealthcare #Neuromodulation #Gastroenterology

📍 Expanding access to pediatric GI care in Greenfield, WI We’re pleased to recognize a new location now offering IB-Stim® as part of the care pathway for children and adolescents ages 8–21 with functional abdominal pain associated with IBS and functional dyspepsia. Pictured left to right: Brittany Framke, RN | Dr. Zahra Nouri | Ashley Tirado, MA IB-Stim is a percutaneous electrical nerve field stimulator (PENFS) system designed to aid in the reduction of abdominal pain when used as part of a comprehensive treatment approach for disorders of gut-brain interaction. We appreciate the continued efforts of care teams working to expand access and support patients within their local communities. For important IB-Stim information, including indications, precautions, IFU, and contraindications, visit: ibstim.com/important-info… #IBStim #PediatricGI #FunctionalAbdominalPain #FunctionalDyspepsia #PediatricHealthcare #Gastroenterology #Neuromodulation #DGBI

NeurAxis is at the Society for Pediatric Pain Medicine (SPPM) Annual Meeting in Denver. 📍 Sheraton Denver Downtown 🗓 Educational Symposium: March 11 🗓 Annual Meeting: March 12 Our team is excited to be in Denver to educate and answer questions about IB-Stim®, an FDA-cleared device for children and adolescents ages 8 years and older with functional abdominal pain associated with IBS and functional dyspepsia. If you're attending SPPM, stop by our booth during  exhibit hours to connect with our team and learn more about how IB-Stim fits into the care pathway for pediatric patients. 👥 Doug Terry, Brian Carrico, Eric Jakel, and Adrian Miranda are onsite. Learn more about IB-Stim: ibstim.com/how-ib-stim-wo… For important IB-Stim information, including indications, precautions, IFU, and contraindications, visit: ibstim.com/important-info… #SPPM2026 #PediatricPain #PediatricGI #IBStim #FunctionalAbdominalPain #Neuromodulation #PediatricHealthcare

We’re pleased to welcome Hackensack Meridian Health K. Hovnanian Children’s Hospital at Jersey Shore University Medical Center as a newly trained program offering IB Stim®. After completing IB Stim training, the pediatric GI team at K. Hovnanian Children’s Hospital is now equipped to provide an FDA-cleared, drug-free device for patients ages 8 and older who suffer from functional abdominal pain due to IBS, functional dyspepsia (FD), and FD-related nausea symptoms. The whole Neuraxis team is proud to support your continued leadership in pediatric functional GI care! For important IB Stim information, including indications, precautions, IFU, and contraindications, visit: ibstim.com/important-info… #IBStim #PediatricGI #FunctionalAbdominalPain #PediatricGastroenterology #ChildrensHospital #HackensackMeridianHealth #EvidenceBasedCare #NewJersey

IB-Stim provides a non-pharmacologic approach for functional abdominal pain in patients with IBS or functional dyspepsia (FD), and for nausea symptoms in FD. In one study, 81% of patients experienced improvement in global symptoms, with no serious adverse events reported.¹ Learn more about IB-Stim: ibstim.com/how-ib-stim-wo… For important IB-Stim information, including indications, precautions, IFU, and contraindications, visit: ibstim.com/important-info… ¹ Study data available at ibstim.com/ifu #IBStim #FunctionalAbdominalPain #FDNausea #PediatricGI #EvidenceBased

IB-Stim is the first FDA-cleared, drug-free technology indicated for the reduction of functional abdominal pain associated with IBS and FD in patients ages 8 and older. It uses Percutaneous Electrical Nerve Field Stimulation (PENFS) to engage central pain pathways. This option complements existing care strategies without medications or surgery. Learn more about IB-Stim: ibstim.com/how-ib-stim-wo… For important IB-Stim information, including indications, precautions, IFU, and contraindications, visit: ibstim.com/important-info… #IBStim #PediatricGI #FDAcleared #FunctionalAbdominalPain #ClinicalSupport

IB-Stim is FDA-cleared for patients ages 8 and older with functional abdominal pain associated with IBS or functional dyspepsia (FD). It delivers low-frequency stimulation to cranial nerves in the ear, targeting pain-processing regions in the brain. This non-drug neuromodulation option is administered in the outpatient setting, typically for 120 hours per week, for 4 consecutive weeks. Learn more about IB-Stim: ibstim.com/how-ib-stim-wo… For important IB-Stim information, including indications, precautions, IFU, and contraindications, visit: ibstim.com/important-info… #PediatricGI #FunctionalAbdominalPain #IBStim #Neuromodulation #ClinicalCare

Medical coverage expansion can directly influence which care options are available to patients. With recent policy updates expanding access to approximately 45 million additional covered lives, the total number of individuals with potential coverage for IB-Stim® now exceeds 100 million. IB-Stim supports providers who care for children and adolescents 8 years and older with functional abdominal pain associated with IBS, functional dyspepsia (FD), or FD-related nausea symptoms. Learn more: neuraxisinc.gcs-web.com/news-releases/… For important IB-Stim information, including indications, precautions, IFU, and contraindications, visit: ibstim.com/important-info… #HealthcarePolicy #IBStim #PediatricGI #PracticeManagement #GIProviders

As of January 1, 2026, Category I CPT code 64567 is officially active. This update represents an important step forward for providers delivering PENFS procedures, such as IB-Stim®, by improving clarity in billing and coding processes. IB-Stim supports providers who care for children and adolescents 8 years and older with functional abdominal pain associated with IBS, functional dyspepsia (FD), or FD-related nausea symptoms. As practices adapt to this change, alignment between clinical, billing, and administrative teams will be key to successful implementation. For important IB-Stim information, including indications, precautions, IFU, and contraindications, visit: ibstim.com/important-info… #IBStim #PediatricGI #FunctionalAbdominalPain #CPT64567 #PENFS #GIPractice #NeurAxis

10 more days to go to meaningful change in patient access! This update will provide greater clarity in billing and coding for PENFS procedures such as IB-Stim®, supporting providers who care for children and adolescents  8 years and older with functional abdominal pain associated with IBS, functional dyspepsia (FD), or FD-related  nausea symptoms. As we approach this important milestone, we’ll continue sharing information to help pediatric and GI practices prepare for the transition. For important IB-Stim information, including indications, precautions, IFU, and contraindications, visit: ibstim.com/important-info… #IBStim #PediatricGI #FunctionalAbdominalPain #CPTUpdate #PENFS #Gastroenterology #NeurAxis

Percutaneous electrical nerve field stimulation (PENFS) is a targeted, non-drug approach to pediatric functional abdominal pain. IB-Stim® is the first FDA-cleared PENFS device for use in children and adolescents 8 years and older with functional abdominal pain associated with IBS, functional dyspepsia (FD), or FD-related nausea symptoms. This wearable outpatient device is backed by clinical research and designed to fit into routine pediatric GI care. Explore how IB-Stim fits within your current model of care: ibstim.com/how-ib-stim-wo… For important IB-Stim information, including indications, precautions, IFU, and contraindications, visit: ibstim.com/important-info… #IBStim #PediatricGI #FunctionalAbdominalPain #Neuromodulation #FDAcleared #Gastroenterology

Constipation is not always caused by the colon. For many patients, the challenge lies in pelvic floor muscle coordinationduring bowel movements. RED™ enables immediate screening at the point of care to help determine whether pelvic floor therapy or another management approach is appropriate. No software. No large capital investment. Learn more: red4constipation.com For important RED information, including indications, precautions, and contraindications, visit: red4constipation.com/information #RED #PelvicFloor #ConstipationCare #Gastroenterology #MotilityDisorders #NeurAxis

☕ Espresso Station Happening TODAY at NASPGHAN! Visit Booth #314 to meet the NeurAxis team and learn more about how IB-Stim® supports clinicians managing functional abdominal pain associated with IBS and FD in children and adolescents 8 years and older. Our team including Brian Carrico, Ryan Kuhlman, Doug Terry, Matt Carrico, and Trisha Baumgardt are available throughout the day to answer questions and share insights. Grab a cup of ☕️ coffee from our espresso station and stop by to say hello. For important IB-Stim information, including indications, precautions, IFU, and contraindications, visit: ibstim.com/important-info… #NASPGHAN2025 #IBStim #PediatricGI #FunctionalAbdominalPain #BrainGutAxis #Gastroenterology #NeurAxis

📅 Less than 60 days until meaningful change in patient access. Beginning January 1, 2026, Category I CPT code assigned to Percutaneous Electrical Nerve Field Stimulation (PENFS) procedures will take effect. This update enhances clarity for providers delivering PENFS procedures, such as IB-Stim®, to children and adolescents 8 years and older with functional abdominal pain associated with IBS or functional dyspepsia (FD). Stay tuned for more educational updates on this important milestone. For important IB-Stim information, including indications, precautions, IFU, and contraindications, visit: ibstim.com/important-info… #IBStim #PediatricGI #FunctionalAbdominalPain #CPTUpdate #PENFS #Gastroenterology #NeurAxis