Norbert de BREK

Unveiling the Clinical Potential of Prostate Cancer Three-dimensional Models: A Systematic Review euoncology.europeanurology.com/article/S2588-… Patient-derived organoids and slice cultures provide 3D models that preserve #ProstateCancer architecture and molecular features. This systematic review found variable establishment success but strong genomic🧬 fidelity, maintaining key alterations and tumor heterogeneity. Organoids enable biomarker🎯 discovery and drug testing, reflecting clinical responses and resistance mechanisms. Despite limitations such as low scalability and absent microenvironment, these models show strong potential as precision oncology tools for personalized treatment strategies. @ArthurPeyrottes @NorbertDEBREK @MRoupret @UrologieParis @MejeanArnaud @CharlesDariane @OncoAlert 🚨 @Silke_Gillessen @AOmlin @weoncologists

Bravo @NorbertDEBREK pour cette superbe vidéo des points clefs de la continence lors de la prostatectomie #prostatecancer #CFU2024

Quand les internes du service sont si heureux pour leur dernier jour, c’est presque inquiétant ! 😂 Bonne continuation ! @HopitalPompidou @APHP @AlexandreIfrah @grembr @SarahSerezo @NorbertDEBREK @AccarainAnna