NotOstriching
21.2K posts
@NotOstriching
Class of xbb 1.5, “the kraken” “A thorn of experience is worth a wilderness of warning.” U can fool some of the people all of the time…” 🙏 to those not fooled
What type of doctor do you go to for help with neuroinflammation from covid vaccine? Is it a neurologist? It seems to get worse with each passing day. The past two days it’s felt like my brain is on fire. I’m sitting here with an ice pack now, but it’s not helping. Thanks
This is going to be worse than COVID. We are screwed.
@drpjhughes @Channel4News @wesstreeting Have you noticed that WHO put the site about meningococcal Meningitis down? I googled who meningococcal Meningitis and clicked the result: who.int/error-pages/404 The one where it was said that transmission is via aerosols.
For many people, COVID did not end when the infection cleared - it evolved into a longer and far more complicated story. This paper presents Long COVID as a heterogeneous, multisystem condition that can affect nearly every organ system🧵
New Survey: 50% of kindergarten teachers report their students are having more difficulty using bathroom on their own? Look, schools cannot function if parents don't do even the basic minimum in teaching their own children to toilet independently What a disheartening survey
Overview and Pathophysiology of Long COVID 🚨200–400 MILLION people worldwide are crippled by Long COVID. That's not a 'mild' virus aftermath, it's multi-organ destruction that persists for years. Wake up. #LongC0vid ➡️Authored by @elisaperego78 , a Long COVID patient-researcher and advocate (with lived experience of chronic illness), it brings authenticity and depth rarely found in traditional academic reviews, blending rigorous synthesis with real-world urgency.💪👏 ➡️Summary: 1. Long COVID affects an estimated 200–409 million people globally, with pooled prevalence around 36% across studies. Risks persist across all ages, even in mild/asymptomatic or vaccinated/Omicron cases, though attenuated by vaccination, 2. It is a heterogeneous, multi-system condition involving dozens of symptoms (e.g, fatigue, brain fog, dyspnea, pain) that evolve over time, often relapsing, with potential for subclinical damage, disability, and increased mortality, 3. Major pathophysiological mechanisms include viral persistence in tissues, immune dysregulation (e.g, lymphopenia, T-cell exhaustion, autoantibodies, complement issues, mast cell activation), autoimmunity, endothelial dysfunction, micro/macro-thrombosis (including fibrinolysis-resistant microclots), chronic inflammation, microbiome dysbiosis, and reactivation of latent pathogens, 4. Organ-specific involvement is widespread: cardiovascular/endothelial (e.g, vasculopathy, accelerated aging, perfusion defects), heart (myocarditis, arrhythmias, ischemia), lungs (fibrosis, thrombosis, perfusion abnormalities), CNS (neuroinflammation, Gray matter loss, BBB disruption), PNS (neuropathy, dysautonomia/POTS-like), GI (dysbiosis, barrier impairment), hepatobiliary/pancreas (injury, new-onset diabetes), kidney (progression to CKD, thrombotic microangiopathy), 5. Evidence draws from imaging (e.g, CMR showing up to 78% cardiac involvement post-mild infection), histology/autopsy (viral presence, thrombi, NETs), and large meta-analyses (e.g, 97 million people showing elevated autoimmune disease risk), 6. Challenges include heterogeneous case definitions (WHO, NICE, etc.), limited biomarker access, surveillance gaps post-2022, and reinfection contributions. ➡️‼️In short, this isn't just another review, it's a patient-powered wake-up call exposing Long COVID as one of the most complex, widespread, and under-addressed biological crises of our era. ‼️So, Long COVID represents a profound, enduring public health crisis driven by persistent viral and immune-mediated multi-organ destruction, with no resolution in sight without urgent, scaled-up research and intervention. #WAKEUP #AvoidSars2 #AvoidReinfections
