Osteoarthritis and Cartilage Journals

New in this month's issue 👀 🚶‍♀️ Pathological hypoxia of the medial aspect of the tibial tuberosity during walking appears specific to patients with knee #osteoarthritis BMLs Read for free from Nakanishi et al. - oarsijournal.com/article/S1063-…

🔥 New this month about #metformin 💊 10 year cumulative #osteoarthritis incidence in metformin initiators were 3% lower than non-initiators Read more from Magnusson et al. - oarsijournal.com/article/S1063-…

Are pathologies on ultrasound connected to knee osteoarthritis symptoms? Find out more in this systematic review of > 10,000 knees by Siddiq et al for free in this months issue - oarsijournal.com/article/S1063-… @vickyduong @ProfDavidHunter

🤔 Are clinical guidelines for knee osteoarthritis failing the global population? This months Editors Choice (Clinical) looked at 241 RCTs to reveal some blind spots 👇 Read for free from Low et al. - oarsijournal.com/article/S1063-… @DrDanilo_Silva @DrChrisBarton @AllisonEzzat

New in #OAC Cartilage breakdown in #OA is driven by proteinases. Wilkinson et al. stresses that understanding and measuring proteinase activity - or historical evidence of activity - should be an important consideration in basic OA research. Read more 🔗: sciencedirect.com/science/articl…

New study by @swoodsbio et al. develops a human pluripotent stem cell model to study growth plate development and uncover pathogenic mechanisms in a rare cartilage disease. #PluripotentStemCells #DiseaseModel #Cartilage Read more 🔗: oarsijournal.com/article/S1063-…

#New in #OAC Cartilage shear strain measured by MRI 6 months after ACL reconstruction distinguishes symptomatic from asymptomatic knees—offering a potential early marker of osteoarthritis risk. #MRI #ACL #osteoarthritis #biomechanics Read more 🔗: oarsijournal.com/article/S1063-…

🚀 OAC is on the rise! The 2025 Journal Impact Factors just dropped and OAC continues to be one of the top journal destinations for our community. Huge congratulations and thanks to our dedicated editors, authors, reviewers, and staff! Let's keep the momentum going. 📈

How does silencing Linc01152 increase SOX9 expression?🧐 Check out this new work in #OAC byMai et al. oarsijournal.com/article/S1063-…

New in #OAC! A new high throughput screen of #FDA approved compounds finds the MEK inhibitor trametinib as a promising compound for drug repurposing for osteoarthritis disease modification. @UNCTARC Read more 📚:oarsijournal.com/article/S1063-…

🤔 How can reviewers better identify dubious papers in this age of #AI #LLMs? In this short presentation first given at the recent @OARSInews conference, Ben Faber MD PhD presents published examples and how best to manage them 👇 👇 👇 youtu.be/ghAHsZhZzMc?si…

Did you know bile acids (BA) might influence joint health? The presence of BA receptors in synovial tissue, along with detectable BAs in synovial fluid and their impact on synovial cells, suggests a unique biological role for BAs in joint inflammation. 🔗oarsijournal.com/article/S1063-…

👀 Must read in this month's issue on new early imaging biomarkers of osteoarthritis Read for free by Gareth Jones et al. - oarsijournal.com/article/S1063-…

🔥 Just out! The first of OAC's Osteoarthritis "Fundamental series" covers #diagnosis and #assessment A clinician’s diagnosis is a vital step to facilitate access to and engagement with treatment. Read more from Lauren King and Abhishek Abhishek here: oarsijournal.com/article/S1063-…

🔥 New this month! What are the effects of Sustained Release Calcium Butyrate (SRCaBu) on gut microbiome composition and function in hand OA patients? Read for free from Merel Hartog et al. - oarsijournal.com/article/S1063-…

🩺🤖 How close are we to seeing Generative AI in everyday osteoarthritis care? Read more from Fairley et al. in this month's issue: oarsijournal.com/article/S1063-…

📈Knee arthroplasty in OECD countries has hit a tipping point New study by Backes, Pabinger, Lothaller & Geissler tracks 25 countries over 17 years and found that patients under 65 now make up >50% of all procedures - up from ~37% in 2005. Read for free: oarsijournal.com/article/S1063-…

#New this month our #Basic #Science Editor's Choice for #June. PAR2 in bone accelerates late-stage OA, showing bone turnover’s key role in joint damage and the age- and cell-specific complexity of PAR2. #Osteoarthritis #BoneHealth Read more 🔗: sciencedirect.com/science/articl…

🔥 New in this month's special issue! For osteoarthritis interventions to work long-term, we have to stop treating exercise as just a "treatment" and start focusing on behavior change theory to build sustainable habits. Read more from Pellegrini et al: oarsijournal.com/article/S1063-…

📉 High placebo response is a major hurdle in knee osteoarthritis trials. A new study shows that Screening Period Pain Inconsistency when a patient's pain worsens right before randomization strongly predicts a massive, long-term placebo response.🔬 oarsijournal.com/article/S1063-…