Osteoarthritis and Cartilage Journals

Can hsCRP help us identify an "inflammatory phenotype" in knee osteoarthritis? New data from the NIH-funded MOST Study (n=792) suggests the answer is likely no. Read more from George et al. - oarsijournal.com/article/S1063-…

🦴Is waiting for knee replacements (TKR) slowing down drug discovery? Using intermediate endpoints might make trials faster: 🔹CKOASO: Cuts sample size from 3,000 to 229 🔹esKOA: Strongest predictor of future TKR (5.7RR) 🔹FNIH: High feasibility doi.org/q5p8

⏰ ICYMI Special issue on OA and obesity deadline has been extended to Jun 1 2026. More information can be found here: sciencedirect.com/special-issue/…

The way we talk about OA matters. 🦴 "Wear and tear" feels final, but OA is about resilience and movement. Our latest editorial highlights 4 metaphors from our 2025 competition to redefine the OA narrative. Which one resonates with you? 👇 oarsijournal.com/article/S1063-…

Therapeutics given to the knee joint are rapidly cleared. In this work, Boyer et al. engineered a cationic Interleukin-1 Receptor Antagonist (catIL-1RA) to target anionic cartilage and form drug depots within the joint. Read more: oarsijournal.com/article/S1063-…

The incidence of #OA is higher is postmenopausal #women compared to aged matched #men... Chen et al. links the osteoclast secreted galectin-3 to articular cartilage degeneration in rats! Check out this work 📑 : oarsijournal.com/article/S1063-…

#ACL injury initiates #PTOA via two distinct processes: initial injury of the cartilage surface and secondary joint instability. Takahata et al. aimed to reveal the individual effects of cartilage compression and joint instability on PTOA progression. 🔗 oarsijournal.com/article/S1063-…

Live from the OARSI Word Congress 2026 in Florida! 🌴☀️ Did you know that all papers submitted to OAC undergo statistical review? Rigorous and time-consuming, but very important. Led by the amazing team of Jamie Collins Robin Christensen and Aleksandra Turkiewicz

🗞️Today's Headline🗞️ Preventing osteoarthritis after ACL injury: The case for targeting pre-osteoarthritis illness @OACJournal @Harkey_MS @jbdriban @AIRLabsMSU @oaactionallianc @OAClinicalRes pubmed.ncbi.nlm.nih.gov/41391746/

Live from the OARSI Word Congress 2026 in Florida! 🌴☀️ OARSI President @dr_englund highlighting the top reviewers for OAC at his opening address 🥳 Augustin Latourte André Struglics Rachel E. Miller Dr Thomas Perry Alice Courties Matthew Harkey

We are just 2 DAYS away! Can't wait to see you at #OARSI !

Are we targeting the wrong metrics in #kneeOA? 🦴 New research shows that long-term cartilage health is linked more to reductions in compressive & shear forces than standard knee moments. Time to rethink our targets for gait retraining? oarsijournal.com/article/S1063-…

Can an app help people stick to their knee OA exercises? New research from @CHESM_unimelb's @HinmanRana and team in @OACJournal says yes 📱🦵 A mobile exercise messaging app significantly improved adherence to home strength programs in a new RCT. 👇 oarsijournal.com/article/S1063-…

Join us for the annual @OARSInews PTOA Discussion Group Meeting on Friday 24 April @ #OARSI2026 We will be sharing updates from our PTOA research priority setting, definition & prevalence working groups - lots of opportunities to get involved

Can a mobile app help people stick to their knee rehab? 📱🦴 A new RCT found that using the "My Exercise Messages" app doubled the likelihood of patients staying adherent to their home strength program for knee osteoarthritis. 👀 Read more from Hinman: oarsijournal.com/article/S1063-…

🤔 What are the effects of long-term bed rest unloading on knee articular cartilage? Read more about this 60-day head-down bed rest study to simulate weightlessness in this month's issue - oarsijournal.com/article/S1063-…

Getting geared up for OARSI?🤩 Mark your calendars for the OAC/OAC Open Journal Session on April 23rd, 2026 11 am-12:30 pm EST. 🌴

🆕 New Apr Clinical Editors Choice! 🤔 The prevailing dogma in knee OA is that cartilage has no (intrinsic) repair capacity ⏰ However, regenerative treatments such as knee joint distractions suggest that cartilage repair is possible ⁉️ Read more here - oarsijournal.com/article/S1063-…

Our #Basic #Science infographic for the month of #April is this work by Sun et al. This work investigates the role of ac4C modifications in cartilage endplate degradation as a result of excessive compression. Read more: sciencedirect.com/science/articl…

#Osteoarthritis (OA) often coexists with metabolic traits (MTs), causing significant disability. 🧬 Liao et al. aimed to uncover the shared genetic mechanisms between OA and MTs, revealing novel OA-MT related genes, proteins and pathways. Read more🔖: oarsijournal.com/article/S1063-…