Olivia Teter

I am excited to share our work in which we conducted a CRISPRi-based screen to assess 102 Autism Spectrum Disorder (ASD) risk genes in microglial uptake of synaptic material! (1/7) biorxiv.org/content/10.110…

@SigmaAldrich @AmandaKMcQuade this is happening #SigmaAldrichChocolate

How to Enter: 🍫 Follow @sigmaaldrich 🍫Reply to this post and tag a friend you'd love to share the chocolates with 🍫 #SigmaAldrichChocolate

It’s World Chocolate Day, and we’re excited to announce that we’re giving away our famous Sigma-Aldrich chocolate bottles!

CRISPR has the potential to cure many genetic diseases, but it’s notoriously hard to use in neurons. In this work we tackled 2 of the main hurdles: Cas9 delivery and DNA repair. And we discovered… The rules of genome editing are different in neurons👇🏾 biorxiv.org/content/10.110…

@domjacri Thank you!

@OMTeter Congratulations, very neat study & approach!

I am excited to share our work in which we conducted a CRISPRi-based screen to assess 102 Autism Spectrum Disorder (ASD) risk genes in microglial uptake of synaptic material! (1/7) biorxiv.org/content/10.110…

@IliaVainchtein Thanks, Ilia!

@OMTeter Congrats Olivia!

@MatBVictor Thank you!!

@OMTeter Cool work, congrats Olivia!! 👏👏👏

@WillRFlanigan Could not have done this without our practice presentations, troubleshooting over dinner, and TC playlists!! 🧪🪩

A truly phenomenal tour de force by my best friend! Incredible work linking an ASD risk gene to synaptic engulfment by microglia. Congrats!

@oso_de_antojos Thanks, Santi!😁

@aslfricardo Thanks, Ricardo!

@OMTeter Awesome work! Congrats, Olivia!

Lots of gratitude and awe for everyone who helped contribute to this work through mentorship, scientific advice, and collaboration! @MartinUCSF, @DraegerNina, @sydsat, @AmandaKMcQuade, Brandon Holmes, and @KampmannLab(7/7)

We dove deeply into characterizing how ADNP affects microglia. We found loss of ADNP leads to decreased endocytosis, a remodeled surface proteome, and increased motility. (6/7)

Microglia activation is commonly seen in ASD and abnormal microglial synaptic remodeling has been speculated to contribute to ASD biology. While expression of ASD risk genes is enriched in neurons, we were surprised to see that microglia express many ASD risk genes! (2/7)

UCSF's Institute for Neurodegenerative Diseases is hosting an open house on November 15, 4-6pm for interested rotation students. Come hear flash talks from each lab and afterward socialize with lab members! See you there! Registration: forms.gle/inFDHPeRwbAWNa…

@asamelson1 🙌

Yes! In addition to upholding transparency and truly promoting scientific dialogue, this new publishing landscape will stand as a great training resource - reading peer reviews will surely help trainees, like myself, think critically about their own research

Are you a future postdoc or incoming @UCSF grad student interested in neurodegenerative disease? Join the Open House of the @INDUCSF to learn about our research and meet PIs and current trainees. Register for online participation by Sept 19 here: forms.gle/URgGeWvgy5DAvC…

@sydsat Congratulations, Syd! Always the pioneer! 🫧🐠

Honored to be chosen to hold the Brewer Fellowship which supports research on model organisms. In the Abitua lab we study annual killifish!