

OU Neuroscience
1.1K posts

@OUNeuroscience
@OUHealth & @OU_Neurosurgery's Neuroscience Grad Prog co-directed by Drs. Smith (@ZacharyASmithMD) & Sherry (@MyOnlyNeuron); Podcast: "Neuroscience Frontier"








📢 New Open🔓 Access Article Alert “Irradiation-induced brain senescence accelerates cardiac aging via systemic mechanisms: insights from transcriptomic profiling” by Rafal Gulej (@RafalGulej) & Zoltán Ungvári (@zoltan_ungvari) et al. 👉 rdcu.be/eRKoK Key Insights: 📌Brain irradiation in mice induces cellular senescence, triggering systemic molecular changes. 📌Transcriptomic analysis shows that this brain senescence activates pathways that lead to cardiac aging, including inflammation and extracellular matrix remodeling. 📌The study suggests that brain aging can drive heart aging, supporting the concept that aging in one organ system can propagate to others through circulating factors. Why It Matters: This work reveals a crucial brain-heart aging axis, highlighting that targeting brain senescence may have protective effects on cardiac aging — a potentially novel interventional strategy in geroscience. #Aging #Senescence #CardiovascularAging #Geroscience #BrainHeartAxis





extremely proud of my student, now colleague from afar- @JeffreyZuccato @OU_Neurosurgery presenting work done @UofTNeuroSurge @UofTSurgery Thank you @theABTA @NeuroOnc for recognition of the work published @NatureMedicine

Huge congrats to @_JenniferIhuoma for Best Student Abstract and talk at the crossroads of dyslipidemia & mitochondrial aging, and to @SherwinTavakol at the @OUneuroscience Symposium. Proud and grateful for the teamwork that made this possible. Team science at its best!👏🧠























