@nomad421 I use Go all the time now.
"If you want me to I’d do these three things next:"
Ok, Go!
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Ola Wallerman🇸🇪
4.1K posts
Ola Wallerman🇸🇪
@OWallerman
PhD in genomics, expert in nanopore sequencing and bioinformatics
Uppsala, Sverige Katılım Ocak 2015
523 Takip Edilen898 Takipçiler
That it kind of sucks. Plus, I already know C, C++, and Rust, so I don't see a clear benefit or use case.
Bidhan@bidhanxcode
Google uses Go. Meta uses Go. Microsoft uses Go. Amazon uses Go. Uber uses Go. Dropbox uses Go. Cloudflare uses Go. Twitch uses Go. Docker uses Go. Kubernetes uses Go. PayPal uses Go. Shopify uses Go. What’s stopping you from learning Go?
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@OWallerman but like, how did you get all 3 on the terminal? I don't remember implementing multifigure plots for terminal output (though, it can just take any plot and render it in the terminal, I don't remember implementing that on for the CLI cause it was too complicated)
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Introducing kuva: A scientific plotting library in rust, along with cli binary with the option to plot directly into the terminal.
Feel free to drop me some feedback as an issue on the repo
github.com/Psy-Fer/kuva
crates.io/crates/kuva/0.…
James Ferguson@Psy_Fer_
Yea your plotting library is cool, but can it do this? (yes, that's plotting in the terminal, with just ascii, utf-8, and ansi)
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@Psy_Fer_ Told Gemini 3 Flash to look at the library, figure out which plots to use and tell me how to adjust line height to make it look nicer :)
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@OfficialLoganK Look the be honest, after testing Gemini3.1 it's not even close to Claude Sonnet and Opuse 4.6.
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Gemini 3 pro did at least give meaningful thoughts. 3.1 is
almost unusable in Antigravity
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I'm now moving forward to the subsequent stage, and considering how to best make progress. The next step is in motion. Now I am moving forward with the execution. I am considering the next action and how to move forward.
SAME%
SAME%
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@nomad421 Not my experience but might be because I only used Claude in Antigravity, guess it is time to get a Claude subscription. Not too impressed with Gemini 3.1 so far...
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Yes; Claude Code is >> Codex; this has been my experience despite what many people have been claiming.
Greeny@greenytrades
Okay SERIOUSLY WTF have I been doing with my life. Claude is 10x better than ChatGPT and I'm only an hour in.
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@nomad421 Opus talks nice but I threw 5.3 at one of my larger projects and this pretty much sums it up...
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@nomad421 @AnthropicAI Even better - ask it to build a bioinformatics framework in rust for agentic programming. No more slow python tools.
For ⭐️ - can send some stats if you have a good testset
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Now let's do the STAR aligner! We have a known "gold standard" reference solution. We just need the token budget and some help from @AnthropicAI!
Anthropic@AnthropicAI
New Engineering blog: We tasked Opus 4.6 using agent teams to build a C compiler. Then we (mostly) walked away. Two weeks later, it worked on the Linux kernel. Here's what it taught us about the future of autonomous software development. Read more: anthropic.com/engineering/bu…
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Plus, the name is already obvious "STARS" (can be abbreviated "STA-RS"!
𝕐@nomad421
Any bioinfo friends out there have a huge load of AI credits & want to try smth crazy (but amazing if it works)? What if we ask Claude to port STAR to Rust? Current dev & maintenance on this central tool has largely stalled, but I think a lang change would reinvigorate it!
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@Psy_Fer_ @kirk3gaard @ATinyGreenCell @The__Taybor It makes sense if they 1) has a big update planned for minion or 2) aim to sell the company, not the sequencers
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@kirk3gaard @ATinyGreenCell @The__Taybor Every hospital I've sold a computer to for runing a P2S was so they could get hands on with the tech, test some pilots, so they could move to clinical testing. That stuff takes time to happen, and it pipelines into P24/48 sales. Removing low price option to try it is a mistake.
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As the person who conceived both devices and led their development- as I stated at London Calling in public - P2S is targeting pioneering users who want flex. P2i is targeting more conservative users who want reliability- so sell appropriately. genomeweb.com/sequencing/oxf…
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@vsbuffalo What do you think will be the biggest win for the field? Will we see faster code for general purpose tasks or "just" more specialized tools?
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Don’t get me wrong. This frontier is great in many ways. People who are better designers than coders will create amazing things. Testing is cheaper! Eventually better software will emerge as a result.
The upper frontier: we can use AI to lower the barrier to excellence.
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IMO there are two frontiers of AI & coding. The bottom frontier: barrier to entry is now close to zero, software is easy to vibe code. Abundance, with slop: we’re going to see bad bugs; risk of scientific papers invalidated when AI inserts fake data or bunk code. New tail risks.
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Should be M pairs/h, not reads. Star is absurdly fast, wonder why it is not used for DNA.
It is time to kill fastQ
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@nomad421 Ok it was not trivial to create an aligner from scratch with STAR speed and functionality, but at least I have some alignments. :)
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@OWallerman I think that there is much room for efficiency improvement (several open issues / PRs in the STAR repo already), but the first goal would just be to produce the same output. I think having STAR written in Rust would make it more approachable & raise interest from maintainers.
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Any bioinfo friends out there have a huge load of AI credits & want to try smth crazy (but amazing if it works)? What if we ask Claude to port STAR to Rust?
Current dev & maintenance on this central tool has largely stalled, but I think a lang change would reinvigorate it!
English
