Organic Syntheses

Synthesis of N-Pyridinium Aziridines Submitting Authors: Samya Samanta, Hao Tan, Saikat Chatterjee, David C. Powers Checking Authors: Michael M. Gilbert and Nathan D. Ide orgsyn.org/demo.aspx?prep…

Simplified Preparation of the (1R,2S)-Berkessel salalen Ligand from cis-1,2-Diaminocyclohexane (cis-DACH) Submitting Authors: Christina Wartmann, Tobias M. Leuther, Hauke Engler, and Albrecht Berkessel Checking Authors: Mengfei Xu and Vy M. Dong orgsyn.org/demo.aspx?prep…

Amination of Aryl Boronic Acids Using O-(Diphenylphosphinyl)hydroxylamine (DPPH) Kasie H. Leung and Richard Y. Liu orgsyn.org/demo.aspx?prep…

Base-Promoted N-Heteroaryl C-H Oxidative Coupling With Alcohols for N-heteroaryl Ether Synthesis Samuel L. Graf 1 and Jeffrey S. Bandar orgsyn.org/demo.aspx?prep…

Iridium-Catalyzed Borylation of Silanes Christina A. Rivera, Benjamin A. Janda, and Neil K. Garg orgsyn.org/demo.aspx?prep…

Preparation of (S,S)-B2bg2, a Chiral Diboron Reagent Cliff Yang, Brooklyn Maddox, Anshu Yadav, Robert E. Maleczka Jr. orgsyn.org/demo.aspx?prep…

Preparation of Hexafluoroisopropyl Sulfamate (HFIPS) for the Sulfamoylation of Alcohols and Amines Mathew L. Piotrowski, Matthew Sguazzin, Jarrod W. Johnson, and Jakob Magolan orgsyn.org/demo.aspx?prep…

Enzymatic Saponification of Esters Containing β-Leaving Groups Benjamin A. Janda, Allison M. Clark, and Neil K. Garg orgsyn.org/demo.aspx?prep…

Umpolung Synthesis of α-Bromo Secondary Amides from Unactivated Hydroxamates Rui Wang, Hao Cao, and Wenbo H. Liu orgsyn.org/demo.aspx?prep…

Professor David Nagib of Ohio State presented the Organic Syntheses Lecture at the UC Irvine on November 3, 2025 on “Harnessing Radicals and Carbenes to Enable Unconventional Reactivity”.

Professo Yoonsu Park of KAIST presented the Organic Syntheses Lecture at the University of Hong Kong on November 5, 2025.

Palladium-Catalyzed Carbonylative Spirolactonization of Hydroxycyclopropanols  Cyrus C. Gudeman, Courtney M. Wiethorn, and Mingji Dai orgsyn.org/demo.aspx?prep…

Preparation of S-Trifluoromethyl Trifluoromethanesulfonothioate (TTST), a Highly Versatile and Atom-economical Trifluoromethylthiolating Agent Seyedesahar Miraghaee, Teruo Umemoto, and Gerald B. Hammond orgsyn.org/demo.aspx?prep…

Synthesis of 4,4-Dimethyl-1,6-Heptadiyne and Derivatives from Dimedone Amir Tavakoli, Nathaniel J. Selvaraj, and Gregory B. Dudley (uh.edu/nsm/chemistry/…) orgsyn.org/demo.aspx?prep…

Professor Emeritus Tohru Fukuyama (University of Tokyo) presented the Organic Syntheses Lecture at Tohoku University on November 6th, 2025.

Discussion Addendum for: Nickel-Catalyzed Synthesis of Ketones from Alkyl Halides and Acid Chlorides: Preparation of Ethyl 4-Oxododecanoate Omar M. Beleh and Daniel J. Weix orgsyn.org/demo.aspx?prep…

Large-Scale Amino-Hydroxylation Using Tethered Nitreniums Shyam Sathyamoorthi (medchem.ku.edu/research/shyam…) orgsyn.org/demo.aspx?prep…

Preparation of N-tert-Butylbenzenesulfinimidoyl Chloride Teruaki Mukaiyama, Yasuo Nakamura, and Jun-ichi Matsuo (yakugaku.w3.kanazawa-u.ac.jp/~gousei/) orgsyn.org/demo.aspx?prep…

Oxidative Nitrogen Atom Insertion into Cyclopentenones Bence B. Botlik and Bill Morandi (@morandilab) (morandi.ethz.ch) orgsyn.org/demo.aspx?prep…

Summer 2026-2027 Research Grants for Faculty at Principally Undergraduate Institutions: Applications are due by November 1, 2025. For more information, visit orgsyn.org/puigrants.aspx