The Patient-Centered Outcomes Research Institute

Thank you @RepMcGarvey for taking the time to meet with PCORI today!

Check out the Engagement in Health Research Literature Explorer, a streamlined resource with more than 2,000 peer-reviewed citations on patient engagement in health research. Learn more: pcori.me/3mM9ZuH

PCORI recently released an Evidence Update on treatment options for genitourinary syndrome of menopause (GSM) — a term that describes a variety of symptoms caused by hormonal changes affecting quality of life for many women during and after menopause. A review of available research from nearly 70 studies on GSM showed that some treatments may help to improve certain symptoms, while others may not. Read more: pcori.me/3TqtaMZ

The latest edition of PCORI’s Emerging Health Care Innovation Brief features FDA approval of treatments for prostate cancer, kidney cancer and T1D, among others. Other topics include: ◾ Cefepime and zidebactam ◾Polymyxin B hemoperfusion cartridge Read more: pcori.me/4guNYwt

Registration is now open for #PCORI26! The PCORI Annual Meeting is the perfect place to learn about recent findings from PCORI-funded CER on a range of topics, including: ◻️ Digital health technologies, such as AI in CER ◻️ Diagnosis and treatment of ADD/ADHD disorder in children ◻️ Physical activity and nutrition pcori.me/4wAkRgb

A PCORI-funded RCT compared 2 programs within primary care to see which was more effective in promoting weight loss: 1️⃣ Enhanced standard of care: Counseling sessions with primary care clinicians 2️⃣ Enhanced standard of care plus family-based behavioral treatment: The above plus counseling sessions with trained health coaches Read the study results: pcori.me/4v2a9O4

Save the Date for #PCORI26! PCORI Annual Meeting will take place Oct. 19-20 at the Marriott Marquis in downtown Washington, D.C. Watch for registration details in the coming soon! pcori.me/4fW2BW0

Several PFAs will open for LOI submissions Aug. 4. To help prospective applicants prepare, PCORI will host virtual Applicant Town Halls for these upcoming funding opportunities. Learn more & register: pcori.me/3SCwGDJ

In a PCORI-funded study, 2 approaches for treating adults with chronic migraines and medication overuse were compared. While the 2 approaches worked about the same to reduce the number of days per month with a migraine, compared to people who continued taking the overused medicine, individuals who stopped taking the overused medicine: ◼️ Had fewer days when they used medication to relieve symptoms ◼️ Were less likely to overuse medication pcori.me/3oRC18z

Strengthen Your Understanding of CER With PCORI’s Research Fundamentals Our free, on-demand training equips you with the tools to participate confidently and meaningfully in patient-centered research, from understanding core principles to exploring how research shapes healthcare decisions. pcori.me/47yscRO

Deadline Approaching: Submit Your Input PCORI is seeking public input on draft research questions for an upcoming systematic review: Surgical Treatment of Adults With Degenerative Lumbar Spinal Stenosis. Deadline to provide feedback is June 29 at 5 pm (ET): pcori.me/4o4VsYN

A final report is now available for the systematic review on Mindfulness-Based Interventions for Well-Being and Mental Health in Children and Adolescents. This review examines current evidence on mindfulness-based interventions to help inform clinical practice guidance and support decision making by physicians, patients and caregivers. pcori.me/3Qbivod

The latest edition of PCORI’s Emerging Health Care Innovation Brief features newly FDA-approved treatments for a rare and aggressive blood cancer, chronic hepatitis D virus infection and complicated UTIs, among others. Other topics include: ◼️ Aglatimagene besadenovec, a nonreplicating viral immunotherapy designed to treat prostate cancer ◼️ Semaglutide, studied as a treatment for alcohol use disorder pcori.me/4f0kpld

A PCORI-funded patient-centered CER study compared three approaches to help individuals with serious mental illness stop smoking: 1️⃣ An educational program for primary care clinicians 2️⃣ PE plus support from a community health worker 3️⃣ Usual care consisting of access to state psychiatric services or outpatient health and mental health services Read more: pcori.me/4rgRQTt

A final report is now available for the systematic review on Mindfulness-Based Interventions for Well-Being and Mental Health in Children and Adolescents. This review examines current evidence on mindfulness-based interventions to help inform clinical practice guidance and support decision making by physicians, patients and caregivers. pcori.me/3Qbivod

Through a PCORI-funded study consisting of 2 patient-centered CER studies, a research team compared 3 ways to make osteoarthritis treatment decisions: 1️⃣ A custom decision support report alone 2️⃣ A custom decision report + online group health coaching sessions 3️⃣ Usual care pcori.me/4omfkWH

PCORI is seeking public input on draft research questions for an upcoming systematic review: Surgical Treatment of Adults With Degenerative Lumbar Spinal Stenosis. Learn more and submit your input: pcori.me/4o4VsYN

Deadline Tomorrow: Public Comments on the Draft Update of PCORI’s Methodology Standards❗ As part of its ongoing efforts to advance patient-centered CER, PCORI is seeking public comment on a comprehensive update to its Methodology Standards for patient-centered CER. Take advantage of this opportunity to help inform the future conduct of patient-centered CER! pcori.me/4tiK65r

A PCORI-funded RCT compared two school-based programs for preventing cavities: 1️⃣ Standard program: sealant and a fluoride varnish 2️⃣ New program: topical silver diamine fluoride and a fluoride varnish Study results showed both programs worked about the same in controlling tooth decay and preventing new cavities. pcori.me/4uzTG4b

Check out the Engagement in Health Research Literature Explorer, a streamlined resource with more than 2,000 peer-reviewed citations on patient engagement in health research. Learn more: pcori.me/3mM9ZuH