PHAGE: Therapy, Applications, and Research

A new paper from @chinantoinette & colleagues shows Xoo phage vB_XORNC02 is strongly lytic, environmentally stable, and >95% identical to Tsukubavirus XPP1. A promising biocontrol option for bacterial leaf blight. Read more: journals.sagepub.com/doi/10.1177/26… @jbancla

🧬 New paper: SARS‑CoV‑2 doesn’t just disrupt the microbiome: it reshapes the phageome. @siddharthstomar & @CsirEvc share their findings showing phage richness skyrockets in infected individuals (79 vs. 28 genera), bacterial diversity drops. Read more: journals.sagepub.com/doi/10.1177/26…

New paper🧬 This review summarises recent advancements in the field of holins and spanins, membrane-disrupting lysis proteins that essentially act as the “clock” of the phage infection cycle, and potential next-gen therapeutics. Read the full review here: doi.org/10.1177/264165…

New paper🧫 This paper characterises a novel lytic phage, ɸKP-C01, against a carbapenem-resistant Klebsiella pneumoniae strain , a major threat to global public health and potential for an epidemic. Read in full here: doi.org/10.1177/264165…

✨New paper K. pneumoniae persists up to 24 h on hospital surfaces, with persistence at 24°C. Osorio et al. from Columbia show a 3‑phage cocktail delivers ~5‑log killing in 6 h and prevents disinfectant‑linked regrowth. Read more here: journals.sagepub.com/doi/10.1177/26…

New article🔎🥼 The efforts of Soviet scientist, Prof M.I. Lurie, towards phage therapy mechanisms in the 1930s. This article would be greatly beneficial to anyone interested in the history of phage therapy and bacteriophages. Read here: doi.org/10.1177/264165…

New paper 🌟 from @DrPrasanthM & team on: Revising SP6’s lysis genes uncovers holin–endolysin–spanin strategies long missed in GenBank—showing how updated phage annotations can drive the next wave of antibacterial innovation. Find more here: lnkd.in/eVXhgZNN

New paper🧪🥼 Dr Mohammed Imam offers a summary of the current landscape of phage therapy research - its hurdles, along with proposed solutions, encouraging case studies, and finally the future of phage therapy. @Mohammed1imam Read the full review here: journals.sagepub.com/doi/full/10.11…

New paper 🌟 🔬 🧫 This paper presents a new episomal genus of Pseudomonas aeruginosa phage isolated from freshwater in Texas, and highlights potential issues with current lysogeny predicting software. Read the full paper here: journals.sagepub.com/doi/full/10.11…

Read our spring issue now! ˚⋆🔬🧪🧫 ⋆˚ Includes: 🥼 A forgotten phage thinker – MI Lurie 🔬 Challenges and solutions in Phage Therapy 🧼Phage as disinfectants against MDR Klebsiella 🦠 COVID-19 and its effect on the Phageome journals.sagepub.com/toc/ptaa/7/1

Pleased to see #taxMyPhage updated to reflect the ICTV Master Species List taxonomy. More details: lnkd.in/ejCFXcVH Standalone tool: github.com/amillard/tax_m… Webserver: lnkd.in/dtbq5pST Thanks @milja001 & @TSPKU for keeping us updated! #phagetaxonomy

Our spring issue is out now! This includes amazing content & findings such as • A forgotten phage thinker – MI Lurie • Challenges and solutions in Phage Therapy • Phages as disinfectants against MDR Klebsiella. Explore further here: journals.sagepub.com/toc/PTA/current

With @TSPKU we have updated to latest ictv database

Spotlighting our highly cited taxMyPhage paper—fast, accurate, easy to use, ICTV‑aligned phage genome classification. Find more here: journals.sagepub.com/doi/10.1089/ph… Contributed by @milja001 & colleagues #taxMyPhage #PhageResearch #Bioinformatics #ICTV #dsDNA

Read our winter issue now🌟 Includes: 🥼 Phage for catheter biofilms 🔬 New Pseudomonas phage genus 🧬 Helicobacter pylori phage 🧪 Phages for bioremediation journals.sagepub.com/toc/ptaa/6/4

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