PHOTOTHERAPORT

💡 Light to treat neurological diseases & pain? It's near! Luisa Camerin at @IBEC explains how the project 🔬#PHOTOTHERAPORT uses photo-switchable drugs 💊activated by light for precise treatment. Learn more: phototheraport.org #Neurology #PainManagement #LightTherapy

🧪 As part of #ShadowDay, LIOS welcomed 48 curious students from 13 Latvian cities! They explored real career paths by shadowing professionals. In biotech, 2 students dove into research & protein structures via #PHOTOTHERAPORT

🌙 Light-controlled sleep circuits: #PHOTOTHERAPORT scientists created photorexin, the first photo-reversible ligand for orexin receptors. It modulates wakefulness & locomotion in vivo with nanomolar precision. 🧠💡 doi.org/10.1007/s00018…

Last week, #Phototheraport researchers came together online for an engaging session on the latest advances in research 🌟 We shared insights, and coordinated efforts to accelerate innovative light-based therapies💡🩺

✨ For World Epilepsy Day, imagine turning seizures off with light... EU project #PHOTOTHERAPORT combines tiny implants + photoswitchable drugs to modulate overactive neurons in real time, opening a new frontier in epilepsy therapy💡💜 #EpilepsyAwarenessDay #NeuroInnovation

⚡ A new light on epilepsy treatment: #PHOTOTHERAPORT scientists designed photoswitchable carbamazepine analogs for non-invasive control of neuroinhibition. doi.org/10.1002/anie.2…

🔦 #PHOTOTHERAPORT scientists created photoswitchable allosteric modulators for M1 receptors, enabling optical GPCR control! doi.org/10.1002/anie.2…

🔦 Meet azocarnil: A #PHOTOTHERAPORT breakthrough: light-controlled GABA_A potentiator enabling reversible neuroinhibition in vivo without side effects. doi.org/10.1021/jacs.4…

🧠 From coma to consciousness: A review with participation of #PHOTOTHERAPORT shows how brain state  identification + neuromodulation (incl. #photopharmacology) could aid recovery in severe brain injuries. doi.org/10.1093/brainc…

🦴 Osteoarthritis affects more than joints. A study  with #PHOTOTHERAPORT participation links inflammation to pain, anxiety & cognitive decline, pointing to urinary biomarkers as disease indicators. doi.org/10.3390/ijms25…

🧩 Light-tuned brain rhythms: Another paper with #PHOTOTHERAPORT participation shows photoswitchable muscarinic drugs can modulate slow waves & block epileptic discharges 🧠💡 doi.org/10.1093/pnasne…

🔬 Light as medicine: #PHOTOTHERAPORT researchers take part in this review showing how light-activated ligands target cholinergic receptors with precision, offering new ways to study memory, cognition & disease ✨ doi.org/10.1002/med.22…

💡 Controlling dopamine with light: A  #PHOTOTHERAPORT study shows how #photopharmacology could transform treatment of Parkinson’s, schizophrenia & addiction 🧠✨ doi.org/10.1002/med.22…

Activitat de divulgació científica de La Nit de la recerca. Centre cívic Casa Golferichs. @BiaMoreno_G @PHOTOTHERAPORT @IBECBarcelona #Fotofàrmacs: ens prenem un medicament en forma inactiva, il·luminem el lloc on necessitem el seu efecte i el medicament es torna actiu localment.

En el marc de La Nit de la recerca, al centre cívic Casa Golferichs, la biòloga i divulgadora científica @BiaMoreno_G @PHOTOTHERAPORT de @IBECBarcelona explica què són els fotofàrmacs i com funcionen i els avantatges que presenten aquests nous medicaments controlats per la llum.

Yesterday, the Phototheraport team had the opportunity to participate in #NitRecerCat25 at the workshop “What are photodrugs & how light can help health” led by Bia Moreno & Nayeli Pérez 🌟💡

💡 Imagine tiny “light bulbs” inside your body that activate medicine only where needed! Join #PhotoTheraport at #NitRecerCat25 for the workshop: What are photodrugs & how light can help health 📍 Casa Golferichs | 🕕 18:00 - 23/09 | Registration required

1️⃣ Taller 23/09 ✨ Descobreix com la llum pot ajudar a la salut! Taller interactiu per a tota la família amb nanomaterials fotosensibles, neurones reals i sons del cervell. 📍 Casa Golferichs | 🕕 18:00 | Cal inscripció 🔗 lanitdelarecerca.cat/taller-que-son…

🔬✨ A la #NitRecerCat25, l'#IBEC porta la ciència a tothom amb activitats gratuïtes de la mà del @PHOTOTHERAPORT i l'@SPM40projectEU 👇👇👇👇

@KMothPoulsen 💡A new frontier in biomedicine with @PHOTOTHERAPORT participation: scientists have used safe, low-intensity infrared light to control heart rate in living organisms, without surgery or implants, with a light-sensitive molecule of azobenzene. 🎉Congratulations to all authors! 🎉

Photoswitchable drugs offer immense #photopharmacological oportunities since the two isomers can have different pharmacological profiles. One challenge is that the #photoswitches need UV or blue light to be modulated. UV and blue light has very low penetration depth in the body