PRX Life

@Princeton This paper is part of our collection on the #physics of #BiomolecularCondensates. See the full collection: go.aps.org/3O4wcUB

This study was conducted by Qiwei Yu, Trevor GrandPre, Andrew G.T. Pyo, Andrej Košmrlj, and Ned S. Wingreen at @Princeton.

Mobile tethers impact both equilibrium and dynamic properties of membrane wetting by #condensates, providing a framework for understanding the implications of tether-mediated condensate-membrane interactions for cellular organization and function. 🔗 go.aps.org/3PGNpEQ

The authors of the paper are @josiah_kratz at @CMUCompBio, @ShilaBanerji at @GeorgiaTech, and their collaborators at @Physics_CMU.

An analysis tracking E.coli in fluctuating nutrient conditions maps out a reaction-network architecture that integrates environmental history to tune future growth, showing how even the simplest organisms implement complex computational strategies. 🔗 go.aps.org/4tyo7GL

This Perspective was written by Arup K. Chakraborty, Anupama Jayaraman, and Daniel P Newton at @MIT.

A Perspective summarizes recent work on how the humoral immune system learns via feedback regulation during antigen re-exposure and outlines key questions at the intersection of statistical physics, machine learning, immunology, and evolutionary biology. go.aps.org/4uPmZzO

This study was conducted by Elle Stark, Aaron True, and John P. Crimaldi at @CUBoulder and Jonathan D. Victor at @WeillCornell.

A study details a framework that connects fluid dynamics with olfactory signal processing and identifies three dominant processes that reformat the source signal when transported by turbulent flow: frequency filtering, spreading, and production. 🔗 go.aps.org/4nuZ5qL

A diel vertical migration (DVM) model identifies 4 distinct swimmer swarm regimes governed by motility persistence and photokinetic bias, clarifying the diversity of DVM and how light gradients shape ecological self-organization. Dive into the paper: go.aps.org/4tb5hWa

Researchers used Normalizing Flows to distinguish between relevant and noise dimensions, characterizing the properties and curvatures of neural manifolds. They then applied their methods to the macaque visual cortex. Read more: go.aps.org/4mZElr0

Simple models are possible if the mutual information between two halves of a system is consistently subextensive and shared information is compressible, offering a way to tame complexity without making assumptions about the nature of the interactions. 🔗 go.aps.org/497ouAH

The work was conducted by @omer_karin at @imperialcollege.

This study proposes that stress-mediated eukaryotic gene-silencing acts as an adaptive learning or proofreading mechanism, enabling silencing systems to selectively retain the repression of harmful elements and reactivate beneficial ones. Check it out: go.aps.org/4nlFrxl

Casey Barkan and Tom Chou at @UCLA authored the paper.

A new mathematical theory captures how individual cell states and intracellular stochastic gene expression drive development and can be reduced to simpler, interpretable models of tissue growth and epigenetic fitness. 📄 go.aps.org/4evkIEW

A highly adaptive form of mechanical proofreading in B cells based on feedback from cell-to-cell contacts may fine-tune their ligand affinity — hinting that this mechanism might be exploited to restrain autoimmunity or enhance vaccine response. 🔗 go.aps.org/48Ss0yG

The study was conducted by J. Morales at @utem, H. N. Ulloa at @PennSAS @PENN_EES, @LastraFrancisca at @dfc_uchile @CienciasUChile, and their colleagues at @usantamaria and @HokkaidoUni.

A new paper presents a 3D model of the diel vertical migration (DVM) of aquatic organisms, incorporating photokinesis, gyrotaxis, and stochastic reorientation to probe how individual swimming behaviors engender DVM patterns on the population scale. 📄 go.aps.org/4tb5hWa

APS Open Science’s first papers are here. Our new community-driven, open access journal supports research at every stage. Read its inaugural papers on controlling the geometry of 3D soliton knots and hybrid materials for ultrafast photonic and optical devices: journals.aps.org/apsos/recent