Amanda Parisi Cesar

EXACTLY!! 🥴

@emieljanson U need to go on shark tank and get this mass produced! 👏👏👏

Been building a distraction free music and audiobook player for my daughter. 🎵

Bro…!

Nuts

Who are the people that actually vote for this 🤢🤷‍♀️

😂

Manhattan needs better leadership. This is a form of Iryna Zarutska all over again : tragic and a failure of the justice system

ボストン大学の研究で、睡眠中の人間の脳内で「老廃物を強制的に洗い流す洗浄プロセスが実行されている」という衝撃的な事実が明らかになりました。 x.com/ChinaNow24/sta… 「睡眠不足は脳に悪い」という抽象的な精神論ではなく、脳脊髄液が波のように押し寄せ、アルツハイマー病の原因となる老廃物を強制的に洗い流すというメカニズムです。 その衝撃的な詳細と生体システムのハックを3つのポイントにまとめました。 1. 老廃物の『排除』 深い睡眠に入りニューロン活動が静まると、頭部から血液が引き下がります。その空いたスペースに脳脊髄液（CSF）がリズミカルな波として流れ込み、日中に蓄積された有害な代謝廃棄物（アミロイドβなど）を物理的に洗い流すシステムが稼働します。 2. 洗浄の『制約』 この強力な洗浄プロセスは、人間が起きている覚醒時には絶対に実行されません。脳波をトリガーとして流体の動きが駆動されるため、睡眠という特定のステータスに移行しない限り、脳脊髄液が流入するスペースが確保されない構造的な制約が存在します。 3. 脳の『最適化』 「徹夜」は単なる疲労ではなく、この物理的な洗浄サイクルを強制的にストップさせ、脳内に有害物質を蓄積させます。将来的な疾患リスクを無効化するためには、睡眠を単なる休息ではなく、脳をメンテナンス時間として最適化する必要があります。

@elonmusk Grok has changed the game!

Just so we are all on the same page... There was never a housing problem. There was an illegal immigration problem. There was never a debt problem. There was a fraud problem. There was never a border problem. There was an enforcement problem. There was never a crime problem. There was a prosecution problem. There was never a homelessness problem. There was a fraudulent NGO problem. There was never a failing school system problem. There was an indoctrination problem. There was never a funding problem. There was a theft problem. There was never a healthcare affordability problem. There was an illegal alien free-load problem. There was never an American dream problem. There was a Democrat problem.

So fascinating

I wish all who celebrate St. Patrick’s Day knew the true meaning of the holiday. It wasn’t established to celebrate leprechauns, the color green, or getting drunk. It was to honor and celebrate the life of a man who preached Christ throughout Ireland. His heart was focused on what matters most. St. Patrick once wrote these words: “Christ with me, Christ before me, Christ behind me, Christ in me, Christ beneath me, Christ above me, Christ on my right, Christ on my left, Christ when I lie down, Christ when I sit down, Christ when I arise, Christ in the heart of every man who thinks of me, Christ in the mouth of everyone who speaks of me, Christ in every eye that sees me, Christ in every ear that hears me.”

Don't be IBM and fumble an 18yr head start on AI IBM was the most valuable company on Earth. Invented the hard drive. The PC. The floppy disk. The ATM. DRAM. SQL. The barcode. Most US patents 29 years straight. 405,000 employees. 70% mainframe market share. Today: $231 billion. 67th in the world. Anthropic. Founded 2021. Four years old. $380 billion. Every piece of the bag was fumbled... Invented the PC. Sold to Lenovo: $1.75 billion. Invented the hard drive. Sold to Hitachi: $2 billion. Server business. Sold to Lenovo. Basically nothing. Now the chips. This is pure comedy. IBM was the largest semiconductor manufacturer on Earth. Fabs in New York. Fabs in Vermont. 16,000 patents. They PAID GlobalFoundries $1.5 billion cash to take it. Gave away the factories. Gave away the patents. $4.7 billion write-down. IBM had American fabs. They paid to close them. And the same Democrats who scream about chips going overseas are the ones whose policies made it too expensive to build here. We wouldn't have TSMC/Taiwan issues today. Decisions have consequences. TSMC: $700 billion. Nvidia: $5 trillion. IBM paid to exit chips right before chips became the most valuable industry on Earth. Incredible timing. Deep Blue beats Kasparov. Live television. First machine to outthink a human world champion. IBM owned AI. Not as a buzzword. As a fact. On camera. In front of the whole planet. OpenAI did not exist for another 18 years. Anthropic for another 24. Nvidia was making cards so teenagers could play Halo. Google was two grad students sharing a dorm room. IBM had an 18-year head start on the entire AI industry. What did they do with it. They dismantled Deep Blue. Put it in a museum. Same mentality as every socialist (cough dems) who wants to regulate AI before it ships. Celebrate the breakthrough. Kill the follow-through. Watson wins Jeopardy. Destroys the two greatest players alive on national TV. Most famous AI brand on the planet. IBM spends billions on Watson Health. AI that cures cancer. Their engineers flagged it unsafe. Instead of fixing it they sold it for scraps. Then killed the brand entirely. Loser mentality. IBM Research. Decades of NLP work. The compute. The talent. The CEO looks at LLMs and says "no thanks." Two years later ChatGPT launches. 100 million users in two months. The entire economy reorganizes around the exact technology IBM looked at and said nah. That is like having Google's algorithm in 1997 and deciding to build a phonebook. The suits and the consultants took over. Same thing that kills every city, every agency, every institution that picks socialism over competition. $201 billion in buybacks over 25 years. More on buybacks than CAPEX. They could have funded every AI lab on Earth with that money. Instead they bought their own stock while the stock went down. Revenue down 22 straight quarters. Nobody fired. Name another job where you lose $95 billion in market cap and get a raise. Actually don't. That job only exists at IBM and in Congress. Buffett bought $12 billion in IBM. The greatest investor alive. Held six years. Dumped it on CNBC. "I was wrong." Put the money in Apple. Best investment in Berkshire history. They had the patents. The labs. The engineers. The brand. An 18-year head start on AI. Replaced the builders with bureaucrats. Chose buybacks over R&D. Chose administration over competition. Lost everything. Now look at who wants to run the same playbook on the AI economy. Bernie wants data center moratoriums. Tax the builders before they finish building. Ro Khanna represents $18 trillion in Silicon Valley market cap. Apple. Nvidia. Google. His district built AI. He just held a Stanford town hall with Bernie called "Who Controls AI: The Oligarchs or The People." Wants to tax unrealized gains. Pause data centers. Put unions on AI boards. Redistribute wealth that hasn't been created yet. His own district is trying to primary him. Not because he's too progressive. Because he's trying to kneecap the industry that made his district the most valuable zip code on Earth. That is IBM energy. Tax the engineers. Slow the builders. Add a committee. Wonder why nothing works. Gavin ran California from a $97 billion surplus into a $68 billion deficit. Lost 789 companies. Tesla. SpaceX. Oracle. Chevron. 200,000 people leaving per year. And he thinks he should have a say in how AI gets built nationally. The guy who can't keep In-N-Out Burger in California wants to regulate the most important technology since electricity. These aren't hypotheticals. This is the IBM playbook in real time. Replace engineers with regulators. Replace competition with committees. Replace building with administrating. And act shocked when the talent leaves and the lead disappears. IBM went from first to 67th. 1.43% a year for 28 years. A savings account beat that. Don't let them do it to America. Name a bigger fumble. I'll wait.

I’m buying my kids more skins 🥹

This is a glory story 💯🙌 looks like the American dream is still alive 💁‍♀️🇺🇸

BLACKROCK JUST BET $100 MILLION ON TRADES, NOT COLLEGE DEGREES BlackRock is putting $100 million into training plumbers, electricians, and HVAC workers as the AI boom runs straight into a shortage of people who can actually build things. Turns out the future still needs someone with tools and a clue. Source: NewsForce

Scientists put kids through 100 hours of reading, then scanned their brains. New wiring had physically grown inside the language regions. Communication between brain areas sped up by a factor of 10. Kids who didn't read showed zero change. That was a 2009 Carnegie Mellon study. It gets wilder. In 2013, Emory University scanned 19 students every morning for 19 straight days while they read one novel chapter each night. Mornings after reading, the brain areas responsible for understanding other people's emotions lit up with new connections. So did the region that processes physical sensation. Their brains were simulating what the characters felt, as if it were happening to them. Those changes stuck around for 5 days after they finished the book. Now flip to scrolling. A massive review published in Psychological Bulletin last September pulled together 71 studies covering 98,299 people. Heavy short-form video use (TikTok, Reels, Shorts) showed a clear pattern: worse attention, weaker self-control, and more anxiety. Consistent across teenagers and adults, across every platform tested. Oxford didn't name "brain rot" its 2024 Word of the Year for nothing. A 2024 brain wave study found that people hooked on short-form video had weaker activity in the front of the brain, the part that controls focus and impulse control. Separate brain scans showed the same thing: heavy scrollers had less activation in the exact regions that deep reading strengthens. UCLA neuroscientist Maryanne Wolf has been studying this for decades. Humans were never born to read. There's no gene for it. Reading is something we invented, and it hijacked neurons that were originally meant for recognizing faces. Over time, it built entirely new brain circuits connecting language, vision, and emotion. But those circuits only survive if you use them. Stop reading, and they fade. Wolf's conclusion is simple: screens built for speed produce a speed-wired brain. Books built for depth produce a depth-wired brain. One honest caveat: most of these studies are snapshots, not long-term tracking. People who already struggle to focus might just prefer short videos. But the same pattern showing up across nearly 100,000 people is hard to shrug off. The tweet repeats the line seven times. The research backs it up with brain scans, EEG data, and white-matter imaging across tens of thousands of people.

· Time ·

Dr. Sabine Hazan shares a jaw-dropping case that changed how she views Alzheimer's: A patient with severe C. diff and dementia (mini-mental status score of 21 — could barely remember anything) received a fecal transplant from his healthy wife. Result? His score jumped to 26, then 29. He started remembering his daughter's date of birth again. The gut-brain axis is real — microbes produce metabolites, toxins, and neurotransmitters (like short-chain fatty acids, GABA, serotonin precursors) that travel via the vagus nerve, bloodstream, and lymphatics to influence brain inflammation, amyloid plaques, and cognitive function. Emerging studies link dysbiosis (especially low microbial diversity) to accelerated neurodegeneration. This wasn't a fluke — it was one of the first documented cases suggesting fecal microbiota transplant (FMT) might reverse some Alzheimer's symptoms by restoring gut balance. Hazan: "That was the beginning of looking at the gut-brain connection… we're at the infancy of the microbiome." What if Alzheimer's — like many neurological conditions — starts in the gut decades before symptoms appear? Would you consider FMT if it could restore memory and cognition? 3:05 clip — one patient, one transplant, massive implications.