Parker Lab

nature.com/articles/s4158… "Balanced plant helper NLR activation by a modified host protein complex" Fine tuning of immune responses

Bioinformatics and functional analysis of EDS1 genes in Brassica napus... sciencedirect.com/science/articl…

"Bioengineering a plant NLR immune receptor with a robust binding interface toward a conserved fungal pathogen effector" Great work from @ZdrzalekR at @mjbanfield lab #BlastOFF pnas.org/doi/10.1073/pn…

Conifers Concentrate Large Numbers of NLR Immune Receptor Genes on One Chromosome academic.oup.com/gbe/article/16…

The Plant Cell in a Nutshell: A phosphorylation module regulates soybean basal immunity plantae.org/a-phosphorylat… @ASPB #PlantSci

📢NEW #Preprint ‼️ Magnum opus of @MarionClavel4 w/ excellent help from many amazing people. Keywords: #autophagy #viruses #modified_self_recognition #immune_signaling. Please let us know what you think.🧵 summarising our key findings

IN BRIEF: From algae to apples: The structural and functional conservation of NLRs (Michael Busche, Bradley Laflamme) buff.ly/3QmUHL7 @JohnInnesCentre @Khongsam_Chia @Phil_Carella @ASPB #PlantSci

Congratulations Jane Parker of @mpipz_cologne, newly inducted NAS international member! #NAS161 #NASmember #genetics #plantbiology

As part of the #50YearsofCell, our focus issue on Immunology is out! ⁠ ⁠ This issue brings Cell’s 50th anniversary celebrations straight to your lymph nodes with reviews, perspectives and more thought-provoking articles on topics ranging from innate immunity to plant immune systems, and immunological strategies for bacterial detection. ⁠ ⁠ In addition, it features research articles on the mapping of the microbiome across metastatic cancers, a time-series reconstruction of human centriole assembly and how an inhibitory ligand acts directly on CD3e to boost tumor-specific T cell cytotoxicity and limit tumor growth.⁠ ⁠ ⁠To read more click here 👉 cell.com/cell/current

The N-terminal domains of NLR immune receptors exhibit structural and functional similarities across divergent plant lineages (Khong-Sam Chia, Jiorgos Kourelis, Albin Teulet, et. al.) buff.ly/3JhE67n @JohnInnesCentre @Khongsam_Chia @Phil_Carella @ASPB #PlantSci

📣New publication out by Schulze-Lefert and Chai @mpipz_cologne @Westlake_Uni on how phase separation plays a role in the immune system of #plants. Now published in @Nature Congratulations! 🥳👏👏 Learn more 👉bit.ly/3PHLH31 #Immunology nature.com/articles/s4158…

Substrate-induced condensation activates plant TIR domain proteins @Nature nature.com/articles/s4158…

A plant immunity protein interacts with a fungal cell wall–degrading enzyme to create immunogenic compounds, according to a new study in Science. Learn more ⬇️ 📄: scim.ag/5Xa #SciencePerspective: scim.ag/5X9

Our story on the origin and evolution of plant PRRs is out @NatureComms ! nature.com/articles/s4146… A short & illustrated summary of this story:

First major paper accepted from the saur lab: tinyurl.com/mv3zjtxr We demonstrate atypical AVR effector function: inhibition of the barley MLA13 NLR by the AVRa13-V2 variant. Thx to the editor and reviewers for their suggestions. With @MerleBS4 & @Emma_Crean_

The @ISMPMI meeting is coming to an end: Plenary Session 8 (chaired by @ParkerLab_MPIPZ) is kicking off with @kseniakrasileva, talking about biodiversity of plant innate immune receptors and pathogen effectors #2023ISMPMI

Great experience on the first day of #2023ISMPMI ! I will present a poster related to glutamate receptor-like channels(GLRs) promoted host cell death in ETI on Monday. Looking forward to seeing you tomorrow at P-166 in Immune Receptors II session during 12:30-13:15.

Join us at #2023ISMPMI Wednesday after lunch! In addition to learning about new scientific approaches and findings, you’ll have the chance to virtually interact in the session. 📱🛜

Please visit her talk and poster. #2023ismpmi #mlkl #concurrentsession1