Murakami Lab

Our postdoc Chun Yang got awarded this year's S. Walter Englander Prize for Postdoctoral Research from @BB_UPenn. It's a nice combination of biochemistry and cryo-EM as well as yeast genetics from the Kaplan lab @TriggerLoop . (pubmed.ncbi.nlm.nih.gov/39287137/)

@TriggerLoop @TriggerLoop @JohnPetrini @brookscrickard1 Thank you very much!! This looks like a great system for yeast overexpression.

Wonderful work from the Tsai lab @KuangleiTsai, revealing mechanism of the Mediator kinase!

We finally identified a residue critical in TSS scanning through a collaboration with @TriggerLoop. academic.oup.com/nar/advance-ar…

@_themovingvan_ @TriggerLoop Thank you!  we are very excited to see this finding.

Congrats @TriggerLoop and @PennMurakamiLab on transcription start site scanning and contributions from everyone’s favorite general transcription factor TFIIH academic.oup.com/nar/article/do…

Humbly sharing my first author paper, Structure of Hir histone chaperone complex. (yeast version of HIRA) Collaborative work from Murakami Lab, @MarmorsteinLab, @GarciaLabMS, @TriggerLoop and thanks for @bradyajohnston's MolecularNode. sciencedirect.com/science/articl… open access.

7-year collaborative work between the Marmorstein Lab, @GarciaLabMS, @TriggerLoop, and my labs finally came out!

A great new review from our amazing @BMBGGUPENN PhD student Leon Palao III, highlighting the use of combining cryo-ET and single particle analysis to investigate structurally heterogeneous DNA-protein assemblies! authors.elsevier.com/a/1iN48,LqArQC…

Happy Monday! Next up for our member spotlights we have our Social Chair, Leon Palao III! He is a 2nd year student in @BMBGGUPENN and is mentored by Kenji Murakami and @yiweichang. His favorite spot on @Penn's campus is Penn Park! And, he loves @sacnas's community outreach!

Our new study led by @BMBGGUPENN grad students @josejgorbea & Leon Palao III combining cryo-EM single particle analysis and single particle cryo-ET to understand the structure and activity of transcription pre-initiation complex on a divergent promoter! cell.com/molecular-cell…

Meet the author: Kenji Murakami @BMBGGUPENN @BB_UPenn cell.com/molecular-cell…