PharmML

Wondering how to implement a model with time-varying clearance in #Monolix? This mini case-study guides you step-by-step and includes several typical models. See also mlxtran.lixoft.com/examples/model… youtu.be/9RrM8NnS0AM

When I was a kid, I loved drawing maps. I'm so thrilled I get to work on the HuBMAP to create a biomolecular map of the human body, with the @NIH and the @NIH_CommonFund. Working with @katycns and @CompCancer to create a coordinate system to navigate this new map! @MultiCellDS

Learn how to export the plots data from Monolix to reuse them with your second favorite software, for example to generate different plots with R. youtu.be/JMyKwv9btbw

The Standard Output: A Tool‐Agnostic Modeling Storage Format - Terranova - 2018 - CPT: Pharmacometrics & Systems Pharmacology - Wiley Online Library ascpt.onlinelibrary.wiley.com/doi/abs/10.100…

Join us for Dr. Nan-Hung Hsieh's seminar on Monday, 9/24 at 3:30 PM in 101B VENI: “Applying a Global Sensitivity Analysis Workflow to Improve the Computational Efficiencies in Physiologically-Based Pharmacokinetic Modeling”

Torsten: Stan Functions for Pharmacometrics Applications - hubs.ly/H0dmR2b0

Our CPT:QSP Perspective on 'Standard Output' is out ascpt.onlinelibrary.wiley.com/doi/epdf/10.10… SO is the younger brother of @PharmML, a tool agnostic format to store PMX and QSP results.

.@MathCancer introduces Physicell - you can find the paper here: journals.plos.org/ploscompbiol/a… #matrixmcsb

Running sequential joint models, initializing a variable with information from the dataset, defining complex parameter-covariate relationships... Regressors are useful in many situations and easy to define in #Monolix. Read on: monolix.lixoft.com/data-and-model… youtu.be/xFOR73swhcg

Time-varying covariates can be used in #Monolix, but they have to be defined in the structural model file. This video shows how. More details: monolix.lixoft.com/faq/complex-pa… youtu.be/ZkUw3mwFi_g

This is crazy and scary! #opioidcrisis

Couldn't find a probability distribution mindmap more complete (or readable 🙂). Extremely useful imho, in particular in ML twitter.com/ProbOntoDB/sta…

Another week, another feature of #Monolix! Today, learn how to encode different types of time-to-event data for flexible modelling in Monolix. #popPK #SurvivalAnalysis More examples at #tte" target="_blank" rel="nofollow noopener">dataset.lixoft.com/description/de… youtu.be/E3oHXlbQU0g

LibSBML version 5.17 has been released! groups.google.com/forum/#!topic/…

I was recently asked to give a stats talk in my department on how to analyse zero-inflated count data, which is a common problem in ecology (and especially behavioural ecology). I came up with this flowchart and thought I'd share it in case it's useful for any of you #rstats

@ProbOntoDB distributions and their relationships in version 2.5

Are you looking for publication-ready diagnostic plots? Monolix allows you to change the appearance of the plots to save high-quality figures. #Monolix #popPK youtu.be/6inJxpmYboM

Congratulations to France Mentre the #ASCPT2018 Sheiner-Beal Award Recipient. Find out more about the Sheiner-Beal award and start thinking if you know a colleague who measures up. bit.ly/2IWoSUj

Find out how to match different types of observations to different model outputs, or use only part of your data set with #Monolix. #pharmacometrics #popPK youtu.be/Z2e2YOJYNtQ

@dataandme @gavincrooks I can also heartily recommend @ProbOntoDB. How distributions and their parameterisations are related. sites.google.com/site/probonto/… @PharmML